NCT01792258

Brief Summary

Tracheostomy is worldwide performed in Intensive Care Unit (ICU). According to the current literature, indication for percutaneous tracheostomy (PDT) in ICU are: difficult prolonged weaning, prolonged mechanical ventilation, loss of airway reflex, copious secretions, upper airway obstruction. Many studies have focused on the comparison between different PDT techniques and complication. The aim of our study is to evaluate the procedural features, complications, ICU mortality, quality of life, post-discharge mortality of patients undergoing different PDT techniques performed in ICU.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
200

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jun 2012

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2012

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

February 6, 2013

Completed
9 days until next milestone

First Posted

Study publicly available on registry

February 15, 2013

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2016

Completed
11 months until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2017

Completed
Last Updated

February 3, 2016

Status Verified

February 1, 2016

Enrollment Period

3.7 years

First QC Date

February 6, 2013

Last Update Submit

February 2, 2016

Conditions

Keywords

Percutaneous tracheostomyIntensive Care UnitIneffective Airway ClearanceWeaning failure

Outcome Measures

Primary Outcomes (1)

  • Safety of percutaneous tracheostomy

    at the beginning and at the end of the procedure

Secondary Outcomes (6)

  • Early complications

    in the first 24 hours from the end of the procedure

  • Late complications

    from the 2nd day ofter the procedure until the ICU discharge (expected average of 2 weeks)

  • Quality of life

    at 3, 6 and 12 months after tracheostomy

  • Evaluation of organ function

    At 3, 6 , and 12 months after tracheostomy

  • Quality of voice

    At 3,6, 12 months after tracheostomy

  • +1 more secondary outcomes

Study Arms (1)

critical ill patients

The investigator will enroll all the critical ill patients undergoing percutaneous tracheostomy performed in ICU

Procedure: Percutaneous tracheostomy

Interventions

Percutaneous tracheostomies will be performed with the kit commercially available in the current clinical practice.

critical ill patients

Eligibility Criteria

Age18 Years - 82 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Criticall ill patients requiring percutaneous tracheostomy in intensive care unit

You may qualify if:

  • age \>18
  • indication for tracheostomy

You may not qualify if:

  • infectious disease of neck

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Genoa

Genoa, Italy, 16132, Italy

RECRUITING

MeSH Terms

Conditions

Nervous System DiseasesHeart Failure

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular Diseases

Study Officials

  • Paolo Pelosi

    Universita degli Studi di Genova

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Paolo Pelosi, professor

CONTACT

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

February 6, 2013

First Posted

February 15, 2013

Study Start

June 1, 2012

Primary Completion

February 1, 2016

Study Completion

January 1, 2017

Last Updated

February 3, 2016

Record last verified: 2016-02

Locations