NCT01722500

Brief Summary

The primary aim of the International Study of Childhood Obesity, Lifestyle and the Environment (ISCOLE) is to determine the relationship between lifestyle characteristics and obesity in a large multi-national study of 10 year-old children, and to investigate the influence of behavioral settings and physical, social and policy environments on the observed relationships within each country.

Trial Health

98
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
7,806

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Dec 2010

Longer than P75 for all trials

Geographic Reach
12 countries

12 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2010

Completed
1.9 years until next milestone

First Submitted

Initial submission to the registry

October 29, 2012

Completed
9 days until next milestone

First Posted

Study publicly available on registry

November 7, 2012

Completed
2.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2014

Completed
Last Updated

February 5, 2016

Status Verified

February 1, 2016

Enrollment Period

4 years

First QC Date

October 29, 2012

Last Update Submit

February 4, 2016

Conditions

Childhood Obesity

Keywords

InternationalChildhoodObesityISCOLEPennington Biomedical Research CenterPBRClongitudinalmultinational

Outcome Measures

Primary Outcomes (3)

  • Testing of Children

    BMI (kg/m2)

    Baseline

  • Testing of Children

    Waist Circumference (cm)

    Baseline

  • Testing of Children

    Percent Body Fat (%)

    Baseline

Secondary Outcomes (2)

  • Testing of Children

    Baseline

  • Testing of Children

    Baseline

Study Arms (1)

10 year old children

500 children with mean age 10.5 years from each of 12 countries

Eligibility Criteria

Age9 Years - 11 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)
Sampling MethodNon-Probability Sample
Study Population

boys and girls who are approximately 10 years

You may qualify if:

  • students 10 years of age

You may not qualify if:

  • has pacemaker or other internal medical devices

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (12)

Pennington Biomedical Research Center

Baton Rouge, Louisiana, 70808, United States

Location

School of Health Sciences at University of South Australia

Adelaide, 5001, Australia

Location

Centro de Estudos do Laboratório de Aptidão Física de São Caetano do Sul (CELAFISCS)

São Paulo, 09501-000, Brazil

Location

Department of Pediatrics, University of Ottawa

Ottawa, Ontario, K1N 6N5, Canada

Location

Tianjin Women's & Children's Health Center

Tianjin, 300070, China

Location

Department of Public Health School of Medicine at Universidad de los Andes

Carrera, Bogata, Colombia

Location

Department of Food & Environmental Sciences, University of Helsinki

Helsinki, 00014, Finland

Location

St John's National Academy of Health Sciences

Bangalore, Karnataka, 560034, India

Location

Department of Exercise, Recreation and Sports Science at Kenyatta University

Nairobi, Kenya

Location

Faculty of Sport Sciences and Physical Education - University of Porto

Porto, 4200-450, Portugal

Location

University of Cape Town

Rondebosch, Cape Town, 7701, South Africa

Location

Department of Health at University of Bath

Bath, BA2 7AY, United Kingdom

Location

Related Publications (36)

  • Katzmarzyk PT, Barreira TV, Broyles ST, Champagne CM, Chaput JP, Fogelholm M, Hu G, Johnson WD, Kuriyan R, Kurpad A, Lambert EV, Maher C, Maia J, Matsudo V, Olds T, Onywera V, Sarmiento OL, Standage M, Tremblay MS, Tudor-Locke C, Zhao P, Church TS. The International Study of Childhood Obesity, Lifestyle and the Environment (ISCOLE): design and methods. BMC Public Health. 2013 Sep 30;13:900. doi: 10.1186/1471-2458-13-900.

    PMID: 24079373RESULT

  • Tudor-Locke C, Barreira TV, Schuna JM Jr, Mire EF, Katzmarzyk PT. Fully automated waist-worn accelerometer algorithm for detecting children's sleep-period time separate from 24-h physical activity or sedentary behaviors. Appl Physiol Nutr Metab. 2014 Jan;39(1):53-7. doi: 10.1139/apnm-2013-0173. Epub 2013 Jun 26.

    PMID: 24383507RESULT

  • Barreira TV, Schuna JM Jr, Mire EF, Katzmarzyk PT, Chaput JP, Leduc G, Tudor-Locke C. Identifying children's nocturnal sleep using 24-h waist accelerometry. Med Sci Sports Exerc. 2015 May;47(5):937-43. doi: 10.1249/MSS.0000000000000486.

    PMID: 25202840RESULT

  • Katzmarzyk PT, Barreira TV, Broyles ST, Champagne CM, Chaput JP, Fogelholm M, Hu G, Johnson WD, Kuriyan R, Kurpad A, Lambert EV, Maher C, Maia J, Matsudo V, Olds T, Onywera V, Sarmiento OL, Standage M, Tremblay MS, Tudor-Locke C, Zhao P, Church TS. Physical Activity, Sedentary Time, and Obesity in an International Sample of Children. Med Sci Sports Exerc. 2015 Oct;47(10):2062-9. doi: 10.1249/MSS.0000000000000649.

    PMID: 25751770RESULT

  • Tudor-Locke C, Barreira TV, Schuna JM Jr, Mire EF, Chaput JP, Fogelholm M, Hu G, Kuriyan R, Kurpad A, Lambert EV, Maher C, Maia J, Matsudo V, Olds T, Onywera V, Sarmiento OL, Standage M, Tremblay MS, Zhao P, Church TS, Katzmarzyk PT; ISCOLE Research Group. Improving wear time compliance with a 24-hour waist-worn accelerometer protocol in the International Study of Childhood Obesity, Lifestyle and the Environment (ISCOLE). Int J Behav Nutr Phys Act. 2015 Feb 11;12:11. doi: 10.1186/s12966-015-0172-x.

    PMID: 25881074RESULT

  • Pereira S, Gomes TN, Borges A, Santos D, Souza M, dos Santos FK, Chaves RN, Katzmarzyk PT, Maia JA. Variability and Stability in Daily Moderate-to-Vigorous Physical Activity among 10 Year Old Children. Int J Environ Res Public Health. 2015 Aug 7;12(8):9248-63. doi: 10.3390/ijerph120809248.

    PMID: 26262632RESULT

  • Gomes TN, Hedeker D, dos Santos FK, Pereira S, Katzmarzyk PT, Maia JA. Why Are Children Different in Their Daily Sedentariness? An Approach Based on the Mixed-Effects Location Scale Model. PLoS One. 2015 Jul 31;10(7):e0132192. doi: 10.1371/journal.pone.0132192. eCollection 2015.

    PMID: 26230652RESULT

  • Gomes TN, Katzmarzyk PT, dos Santos FK, de Chaves RN, Santos D, Pereira S, Champagne CM, Hedeker D, Maia J. Are BMI and Sedentariness Correlated? A Multilevel Study in Children. Nutrients. 2015 Jul 16;7(7):5889-904. doi: 10.3390/nu7075258.

    PMID: 26193311RESULT

  • Katzmarzyk PT, Barreira TV, Broyles ST, Champagne CM, Chaput JP, Fogelholm M, Hu G, Johnson WD, Kuriyan R, Kurpad A, Lambert EV, Maher C, Maia J, Matsudo V, Olds T, Onywera V, Sarmiento OL, Standage M, Tremblay MS, Tudor-Locke C, Zhao P, Church TS; ISCOLE Research Group. Relationship between lifestyle behaviors and obesity in children ages 9-11: Results from a 12-country study. Obesity (Silver Spring). 2015 Aug;23(8):1696-702. doi: 10.1002/oby.21152. Epub 2015 Jul 14.

    PMID: 26173093RESULT

  • LeBlanc AG, Katzmarzyk PT, Barreira TV, Broyles ST, Chaput JP, Church TS, Fogelholm M, Harrington DM, Hu G, Kuriyan R, Kurpad A, Lambert EV, Maher C, Maia J, Matsudo V, Olds T, Onywera V, Sarmiento OL, Standage M, Tudor-Locke C, Zhao P, Tremblay MS; ISCOLE Research Group. Correlates of Total Sedentary Time and Screen Time in 9-11 Year-Old Children around the World: The International Study of Childhood Obesity, Lifestyle and the Environment. PLoS One. 2015 Jun 11;10(6):e0129622. doi: 10.1371/journal.pone.0129622. eCollection 2015.

    PMID: 26068231RESULT

  • Pereira S, Katzmarzyk PT, Gomes TN, Borges A, Santos D, Souza M, dos Santos FK, Chaves RN, Champagne CM, Barreira TV, Maia JA. Profiling physical activity, diet, screen and sleep habits in Portuguese children. Nutrients. 2015 Jun 2;7(6):4345-62. doi: 10.3390/nu7064345.

    PMID: 26043034RESULT

  • Borghese MM, Tremblay MS, Katzmarzyk PT, Tudor-Locke C, Schuna JM Jr, Leduc G, Boyer C, LeBlanc AG, Chaput JP. Mediating role of television time, diet patterns, physical activity and sleep duration in the association between television in the bedroom and adiposity in 10 year-old children. Int J Behav Nutr Phys Act. 2015 May 13;12:60. doi: 10.1186/s12966-015-0221-5.

    PMID: 25967920RESULT

  • Tudor-Locke C, Mire EF, Dentro KN, Barreira TV, Schuna JM Jr, Zhao P, Tremblay MS, Standage M, Sarmiento OL, Onywera V, Olds T, Matsudo V, Maia J, Maher C, Lambert EV, Kurpad A, Kuriyan R, Hu G, Fogelholm M, Chaput JP, Church TS, Katzmarzyk PT; ISCOLE Research Group. A model for presenting accelerometer paradata in large studies: ISCOLE. Int J Behav Nutr Phys Act. 2015 Apr 20;12:52. doi: 10.1186/s12966-015-0213-5.

    PMID: 25927615RESULT

  • Ferrari GL, Oliveira LC, Araujo TL, Matsudo V, Barreira TV, Tudor-Locke C, Katzmarzyk P. Moderate-to-Vigorous Physical Activity and Sedentary Behavior: Independent Associations With Body Composition Variables in Brazilian Children. Pediatr Exerc Sci. 2015 Aug;27(3):380-9. doi: 10.1123/pes.2014-0150. Epub 2015 Apr 22.

    PMID: 25902556RESULT

  • Ferrari GL, Araujo TL, Oliveira L, Matsudo V, Mire E, Barreira TV, Tudor-Locke C, Katzmarzyk PT. Association Between Television Viewing and Physical Activity in 10-Year-Old Brazilian Children. J Phys Act Health. 2015 Oct;12(10):1401-8. doi: 10.1123/jpah.2014-0406. Epub 2015 Mar 31.

    PMID: 25831554RESULT

  • Borges A, Gomes TN, Santos D, Pereira S, dos Santos FK, Chaves R, Katzmarzyk PT, Maia J. A count model to study the correlates of 60 min of daily physical activity in Portuguese children. Int J Environ Res Public Health. 2015 Feb 26;12(3):2557-73. doi: 10.3390/ijerph120302557.

    PMID: 25730296RESULT

  • Gomes TN, Katzmarzyk PT, dos Santos FK, Souza M, Pereira S, Maia JA. Overweight and obesity in Portuguese children: prevalence and correlates. Int J Environ Res Public Health. 2014 Nov 3;11(11):11398-417. doi: 10.3390/ijerph111111398.

    PMID: 25372884RESULT

  • Gomes TN, dos Santos FK, Santos D, Pereira S, Chaves R, Katzmarzyk PT, Maia J. Correlates of sedentary time in children: a multilevel modelling approach. BMC Public Health. 2014 Aug 30;14:890. doi: 10.1186/1471-2458-14-890.

    PMID: 25174736RESULT

  • Muthuri SK, Wachira LJ, Onywera VO, Tremblay MS. Associations Between Parental Perceptions of the Neighborhood Environment and Childhood Physical Activity: Results from ISCOLE-Kenya. J Phys Act Health. 2016 Mar;13(3):333-43. doi: 10.1123/jpah.2014-0595. Epub 2015 Aug 13.

    PMID: 26285040RESULT

  • Borghese MM, Tremblay MS, Leduc G, Boyer C, Belanger P, LeBlanc AG, Francis C, Chaput JP. Television viewing and food intake during television viewing in normal-weight, overweight and obese 9- to 11-year-old Canadian children: a cross-sectional analysis. J Nutr Sci. 2015 Feb 27;4:e8. doi: 10.1017/jns.2014.72. eCollection 2015.

    PMID: 26090104RESULT

  • LeBlanc AG, Broyles ST, Chaput JP, Leduc G, Boyer C, Borghese MM, Tremblay MS. Correlates of objectively measured sedentary time and self-reported screen time in Canadian children. Int J Behav Nutr Phys Act. 2015 Mar 18;12:38. doi: 10.1186/s12966-015-0197-1.

    PMID: 25889903RESULT

  • Mcneil J, Tremblay MS, Leduc G, Boyer C, Belanger P, Leblanc AG, Borghese MM, Chaput JP. Objectively-measured sleep and its association with adiposity and physical activity in a sample of Canadian children. J Sleep Res. 2015 Apr;24(2):131-9. doi: 10.1111/jsr.12241. Epub 2014 Sep 30.

    PMID: 25266575RESULT

  • Chaput JP, Leduc G, Boyer C, Belanger P, LeBlanc AG, Borghese MM, Tremblay MS. Electronic screens in children's bedrooms and adiposity, physical activity and sleep: do the number and type of electronic devices matter? Can J Public Health. 2014 Jul 11;105(4):e273-9. doi: 10.17269/cjph.105.4511.

    PMID: 25166130RESULT

  • Muthuri SK, Wachira LJ, Onywera VO, Tremblay MS. Direct and self-reported measures of physical activity and sedentary behaviours by weight status in school-aged children: results from ISCOLE-Kenya. Ann Hum Biol. 2015;42(3):237-45. doi: 10.3109/03014460.2014.932847. Epub 2014 Jul 15.

    PMID: 25026181RESULT

  • Borghese MM, Tremblay MS, Leduc G, Boyer C, Belanger P, LeBlanc AG, Francis C, Chaput JP. Independent and combined associations of total sedentary time and television viewing time with food intake patterns of 9- to 11-year-old Canadian children. Appl Physiol Nutr Metab. 2014 Aug;39(8):937-43. doi: 10.1139/apnm-2013-0551. Epub 2014 Mar 14.

    PMID: 24892903RESULT

  • Larouche R, Chaput JP, Leduc G, Boyer C, Belanger P, LeBlanc AG, Borghese MM, Tremblay MS. A cross-sectional examination of socio-demographic and school-level correlates of children's school travel mode in Ottawa, Canada. BMC Public Health. 2014 May 23;14:497. doi: 10.1186/1471-2458-14-497.

    PMID: 24886211RESULT

  • Muthuri SK, Wachira LJ, Onywera VO, Tremblay MS. Correlates of objectively measured overweight/obesity and physical activity in Kenyan school children: results from ISCOLE-Kenya. BMC Public Health. 2014 May 9;14:436. doi: 10.1186/1471-2458-14-436.

    PMID: 24885924RESULT

  • Santos MD, Ferrari G, Drenowatz C, Estivaleti JM, de Victo ER, de Oliveira LC, Matsudo V. Association between breastfeeding, parents' body mass index and birth weight with obesity indicators in children. BMC Pediatr. 2022 Oct 18;22(1):604. doi: 10.1186/s12887-022-03641-3.

    PMID: 36258166DERIVED

  • Barreira TV, Broyles ST, Tudor-Locke C, Chaput JP, Fogelholm M, Hu G, Kuriyan R, Lambert EV, Maher CA, Maia JA, Olds T, Onywera V, Sarmiento OL, Standage M, Tremblay MS, Katzmarzyk PT; ISCOLE Research Group. Epidemiological Transition in Physical Activity and Sedentary Time in Children. J Phys Act Health. 2019 Jun 27;16(7):518-524. doi: 10.1123/jpah.2018-0546.

    PMID: 31104544DERIVED

  • Zakrzewski-Fruer JK, Gillison FB, Katzmarzyk PT, Mire EF, Broyles ST, Champagne CM, Chaput JP, Denstel KD, Fogelholm M, Hu G, Lambert EV, Maher C, Maia J, Olds T, Onywera V, Sarmiento OL, Tremblay MS, Tudor-Locke C, Standage M; ISCOLE Research Group. Association between breakfast frequency and physical activity and sedentary time: a cross-sectional study in children from 12 countries. BMC Public Health. 2019 Feb 21;19(1):222. doi: 10.1186/s12889-019-6542-6.

    PMID: 30791951DERIVED

  • Wilkie HJ, Standage M, Gillison FB, Cumming SP, Katzmarzyk PT. Correlates of intensity-specific physical activity in children aged 9-11 years: a multilevel analysis of UK data from the International Study of Childhood Obesity, Lifestyle and the Environment. BMJ Open. 2018 Feb 3;8(2):e018373. doi: 10.1136/bmjopen-2017-018373.

    PMID: 29431128DERIVED

  • Sullivan SM, Broyles ST, Barreira TV, Chaput JP, Fogelholm M, Hu G, Kuriyan R, Kurpad A, Lambert EV, Maher C, Maia J, Matsudo V, Olds T, Onywera V, Sarmiento OL, Standage M, Tremblay MS, Tudor-Locke C, Zhao P, Katzmarzyk PT; ISCOLE Research Group. Associations of neighborhood social environment attributes and physical activity among 9-11 year old children from 12 countries. Health Place. 2017 Jul;46:183-191. doi: 10.1016/j.healthplace.2017.05.013. Epub 2017 May 22.

    PMID: 28544991DERIVED

  • Dumuid D, Olds T, Lewis LK, Martin-Fernandez JA, Katzmarzyk PT, Barreira T, Broyles ST, Chaput JP, Fogelholm M, Hu G, Kuriyan R, Kurpad A, Lambert EV, Maia J, Matsudo V, Onywera VO, Sarmiento OL, Standage M, Tremblay MS, Tudor-Locke C, Zhao P, Gillison F, Maher C; International Study of Childhood Obesity, Lifestyle and the Environment (ISCOLE) research group. Health-Related Quality of Life and Lifestyle Behavior Clusters in School-Aged Children from 12 Countries. J Pediatr. 2017 Apr;183:178-183.e2. doi: 10.1016/j.jpeds.2016.12.048. Epub 2017 Jan 10.

    PMID: 28081885DERIVED

  • Roman-Vinas B, Chaput JP, Katzmarzyk PT, Fogelholm M, Lambert EV, Maher C, Maia J, Olds T, Onywera V, Sarmiento OL, Standage M, Tudor-Locke C, Tremblay MS; ISCOLE Research Group. Proportion of children meeting recommendations for 24-hour movement guidelines and associations with adiposity in a 12-country study. Int J Behav Nutr Phys Act. 2016 Nov 25;13(1):123. doi: 10.1186/s12966-016-0449-8.

    PMID: 27887654DERIVED

  • Harrington DM, Gillison F, Broyles ST, Chaput JP, Fogelholm M, Hu G, Kuriyan R, Kurpad A, LeBlanc AG, Maher C, Maia J, Matsudo V, Olds T, Onywera V, Sarmiento OL, Standage M, Tremblay MS, Tudor-Locke C, Zhao P, Katzmarzyk PT; ISCOLE Research Group. Household-level correlates of children's physical activity levels in and across 12 countries. Obesity (Silver Spring). 2016 Oct;24(10):2150-7. doi: 10.1002/oby.21618. Epub 2016 Aug 25.

    PMID: 27558527DERIVED

  • Wilkie HJ, Standage M, Gillison FB, Cumming SP, Katzmarzyk PT. Multiple lifestyle behaviours and overweight and obesity among children aged 9-11 years: results from the UK site of the International Study of Childhood Obesity, Lifestyle and the Environment. BMJ Open. 2016 Feb 24;6(2):e010677. doi: 10.1136/bmjopen-2015-010677.

    PMID: 26911589DERIVED

MeSH Terms

Conditions

Pediatric ObesityObesity

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Peter T. Katzmarzyk, PhD, FACSM

    Pennington Biomedical Research Center

    PRINCIPAL INVESTIGATOR

  • Timothy S. Church, MD, MPH, PhD

    Pennington Biomedical Research Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Executive Director of Population Science

Study Record Dates

First Submitted

October 29, 2012

First Posted

November 7, 2012

Study Start

December 1, 2010

Primary Completion

December 1, 2014

Study Completion

December 1, 2014

Last Updated

February 5, 2016

Record last verified: 2016-02

Data Sharing

IPD Sharing
Will not share

Locations

CO(1)ZA(1)AU(1)US(1)CN(1)CA(1)FI(1)BR(1)KE(1)IN(1)PT(1)GB(1)