Interobserver Variation in Applying a Radiographic Definition for Acute Respiratory Distress Syndrome (ARDS)

NCT01704066 | Completed

• 2 other identifiers: CCCCTG-2012-ARDS-012012BAI11B05
• Study Type: observational
• Target: 286
• Locations: 1 country
• Sites: 1

Brief Summary

The original American-European Consensus Conference (AECC) definition of Acute Respiratory Distress Syndrome (ARDS) required bilateral infiltrates consistent with pulmonary edema on frontal chest X-ray (CXR), but there is poor inter-observer reliability in interpreting CXR using this definition among intensivists and radiologists. As a result, the newly published Berlin definition of ARDS specified that the CXR criterion should include bilateral opacities consistent with pulmonary edema not fully explained by effusions, lobar/lung collapse, or nodules/masses on CXR. In order to improve inter-observer agreement, the panel have also developed a set of CXRs judged as consistent, inconsistent, or equivocal for the diagnosis of ARDS. The objective of this study is to investigate the impact of this training set on inter-observer reliability in applying the radiographic definition for ARDS.

Conditions

Acute Respiratory Distress Syndrome

Keywords

ARDS; Chest radiograph; Berlin Definition; Inter-observer agreement

Outcome Measures

Primary Outcomes (1)

• inter-observer agreement in the interpretation of CXRs for the diagnosis of ARDS

  immediately after reading the CXRs

Secondary Outcomes (1)

• Impact of the training set on the inter-observer agreement on the interpretation of CXRs

  difference of inter-observer agreement before and after the training course

Interventions

Training and education OTHER

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Intensivists working in the participating ICUs

You may qualify if:

• intensivists working in the participating ICUs

You may not qualify if:

• those who could not participate both questionnaire surveys
• those who have read the reference with the training set of CXRs before the study
• those who have already known the objective of the study

Sponsors & Collaborators

• Society of Critical Care Medicine, China: lead

Study Sites (1)

Peking Union Medical College Hospital

Beijing, Beijing Municipality, 100730, China

Location

Related Publications (1)

• Peng JM, Qian CY, Yu XY, Zhao MY, Li SS, Ma XC, Kang Y, Zhou FC, He ZY, Qin TH, Yin YJ, Jiang L, Hu ZJ, Sun RH, Lin JD, Li T, Wu DW, An YZ, Ai YH, Zhou LH, Cao XY, Zhang XJ, Sun RQ, Chen EZ, Du B; China Critical Care Clinical Trial Group (CCCCTG). Does training improve diagnostic accuracy and inter-rater agreement in applying the Berlin radiographic definition of acute respiratory distress syndrome? A multicenter prospective study. Crit Care. 2017 Jan 20;21(1):12. doi: 10.1186/s13054-017-1606-4.

  PMID: 28107822 DERIVED

MeSH Terms

Conditions

Respiratory Distress Syndrome

Interventions

Educational Status

Condition Hierarchy (Ancestors)

Lung Diseases; Respiratory Tract Diseases; Respiration Disorders

Intervention Hierarchy (Ancestors)

Socioeconomic Factors; Population Characteristics

Study Officials

• Bin Du, MD

  Peking Union Medical College Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor and Director, Medical ICU

Study Record Dates

• First Submitted: October 6, 2012
• First Posted: October 11, 2012
• Study Start: October 1, 2012
• Primary Completion: December 1, 2012
• Study Completion: December 1, 2012
• Last Updated: December 21, 2012

Record last verified: 2012-12

Locations

CN (1)