Key Insights

Highlights

Success Rate

85% trial completion

Published Results

51 trials with published results (9%)

Research Maturity

252 completed trials (47% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

8.2%

44 terminated out of 539 trials

Success Rate

85.1%

-1.4% vs benchmark

Late-Stage Pipeline

9%

51 trials in Phase 3/4

Results Transparency

20%

51 of 252 completed with results

Key Signals

51 with results85% success44 terminated

Data Visualizations

Phase Distribution

342Total
Not Applicable (178)
Early P 1 (3)
P 1 (48)
P 2 (62)
P 3 (39)
P 4 (12)

Trial Status

Completed252
Unknown105
Recruiting76
Terminated44
Withdrawn32
Not Yet Recruiting17

Trial Success Rate

85.1%

Benchmark: 86.5%

Based on 252 completed trials

Clinical Trials (539)

Showing 20 of 20 trials
NCT05600062Not ApplicableActive Not RecruitingPrimary

Influence of NEP Inhibition on Vascular Leak and Inflammation (NEPi-INFLAMMATION)

NCT03017547Phase 2WithdrawnPrimary

A Phase 2 Study of IC14 in Acute Respiratory Distress Syndrome

NCT04909697Phase 4CompletedPrimary

Treatment of ARDS With Sivelestat Sodium

NCT06213779Completed

The Burden of Acute Respiratory Failure in Chinese ICUs: a National Cohort Study

NCT03763773CompletedPrimary

Prediction of Outcomes With a Miniaturized Transesophageal Echocardiography Probe in Patients With Acute Respiratory Distress Syndrome

NCT01435889CompletedPrimary

Long Term (1 Year) Respiratory Sequelae in Children Surviving an Acute Respiratory Distress Syndrome

NCT02166853Phase 4CompletedPrimary

Effects of SEvoflurane on Gas Exchange and Inflammation in Patients With ARDS (SEGA Study)

NCT04235608Phase 3CompletedPrimary

SEvoflurane for Sedation in ARds

NCT04113434CompletedPrimary

Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome

NCT04524091RecruitingPrimary

Prediction of Inspiratory Effort Response to High PEEP in Patients Recovering From ARDS

NCT06814340Phase 3RecruitingPrimary

"Continuous Positive Airway Pressure on Venovenous extracorporeaL Membrane Oxygenation for Acute respIratory Distress syndrOme"

NCT07511582Phase 2Not Yet Recruiting

Corticosteroids in Hyperinflammatory Phenotype of Critical Illness

NCT06701669Phase 2Recruiting

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort B: Paridiprubart

NCT06701682Phase 2Recruiting

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort A: Vilobelimab

NCT07492888Phase 2Not Yet RecruitingPrimary

Nogapendekin Alfa-Inbakicept and iNKT Cells for Critically Ill Adults With Severe Community-Acquired Pneumonia (With or Without Sepsis/ARDS)

NCT06701656Phase 2Recruiting

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort C: Bevacizumab

NCT06703073Phase 2Recruiting

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS (Master Record)

NCT04305457Phase 2Terminated

Nitric Oxide Gas Inhalation Therapy for Mild/Moderate COVID-19

NCT07466524Completed

suPAR Michigan M2C2 Heterogeneity Validation Cohort Study

NCT07479043Phase 3Not Yet RecruitingPrimary

To Evaluate the Safety and Potential Therapeutic Activity of JadiCell™, an Investigational Umbilical Cord-Derived Mesenchymal Stem Cell Therapy, in Patients Diagnosed With Acute Respiratory Distress Syndrome (ARDS).

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