The Effect of Partial and Complete Sleep Deprivation on Heat Tolerance
Thr Effect of Partial and Complete Sleep Deprivation on Heat Tolerance
1 other identifier
interventional
12
1 country
1
Brief Summary
The purpose of the present study is to evaluate the effect of partial and complete sleep deprivation on exercise heat tolerance. Twelve healthy young male volunteers will participate in the study. They will arrive to our lab four times, in each visit the will undergo VO2 test and Heat Tolerance Test (HTT) after sleeping different amount of hours.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Nov 2012
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
May 6, 2012
CompletedFirst Posted
Study publicly available on registry
May 11, 2012
CompletedStudy Start
First participant enrolled
November 1, 2012
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2013
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2014
CompletedMay 9, 2014
May 1, 2014
1.1 years
May 6, 2012
May 8, 2014
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
oxygen consumption
volunteer's oxygen consumption (VO2) will be monitored continuously with a metabolic chart (ZAN), while running for 10 min on a treadmill under comfortable environmental conditions.Each volunteer will undergo the test 4 times.
experimental days 1,3,4
Secondary Outcomes (3)
Skin temperature
experimental days 2,3,4
Rectal temperature
experimental days 2,3,4
Heart rate
experimental days 1,2,3,4
Study Arms (1)
sleep deprivation
EXPERIMENTALThe research contains only one arm. The subjects will be tested with no sleep deprivation (which will be used as a control measurement) and with partial and complete sleep deprivation.
Interventions
The subjects will visit our labs 4 times. The second visit will be used as the experimental control. During the third and fourth visits the subject will go through an exercise heat tolerance test and a measurement of their physiological efficiency after a partial and complete sleep deprivation, respectively.
Eligibility Criteria
You may qualify if:
- age 18-30
- healthy
- after medical checkup
- after signing concent form
You may not qualify if:
- heart disease
- respiratory disease
- baseline bp above 140/90 mmHg
- sleep disorders
- diabetes
- anhydrosis
- skin disease
- acute illness
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Sheba Medical Centerlead
- International Diabetes Federationcollaborator
Study Sites (1)
Heller Institute of Medical Research
Tel-Hashomer, Ramat-Gan, Israel
Related Publications (1)
Muginshtein-Simkovitch E, Dagan Y, Cohen-Zion M, Waissengrin B, Ketko I, Heled Y. Heat tolerance after total and partial acute sleep deprivation. Chronobiol Int. 2015 Jun;32(5):717-24. doi: 10.3109/07420528.2015.1030409. Epub 2015 May 8.
PMID: 25955404DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Amit Druyan, M.D
The Institute of Military Physiology
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- BASIC SCIENCE
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER GOV
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
May 6, 2012
First Posted
May 11, 2012
Study Start
November 1, 2012
Primary Completion
December 1, 2013
Study Completion
May 1, 2014
Last Updated
May 9, 2014
Record last verified: 2014-05