A Comparative Analysis of Two Types of Exercise on Outcomes Following Total Knee Arthroplasty

NCT01545986 | Completed

• 1 other identifier: 09-04
• Study Type: interventional
• Target: 38
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study was to compare the effects of two exercise programs, using low velocity (LV) and high velocity (HV) contractions, on outcomes of individuals who have undergone total knee arthroplasty (TKA). The experimental hypothesis was that individuals performing HV exercise, compared to LV, would exhibit superior outcomes.

Conditions

Osteoarthritis, Knee

Keywords

Joint Replacement; Exercise; Power training

Outcome Measures

Primary Outcomes (1)

• Change from Baseline in Six Minute Walk Test (6MWT) at six weeks

  The distance walked in six minutes is measured for the 6MWT. A 150 foot hallway is used for the test. Standardized instructions are read to the participant. The participant is asked to walk as fast as he/she feels comfortable and safe in order to walk far as he/she can during six minutes. Distance is recorded in feet and later is converted to meters.

  6 weeks

Secondary Outcomes (6)

• Gait Abnormality Rating Scale (GARS)

  6 weeks

• Change from Baseline in Visual Analogue Scale (VAS) Pain at six weeks

  6 weeks

• Change from Baseline in Timed Up and Go Test (TUG) at six weeks

  6 weeks

• Gait Velocity

  6 weeks

• Change from Baseline in Short Form-36 (SF-36) at six weeks

  6 weeks

Study Arms (2)

High Velocity Exercise

EXPERIMENTAL

The high velocity exercise group performed the concentric contraction phase of resisted exercise in one second or less. This group performed sit to stand exercise, walking, curbs, and stairs as fast as was comfortable without an increased limp. Other exercises were performed at the participant preferred rate.

Behavioral: Exercise

Low Velocity exercise

ACTIVE COMPARATOR

The low velocity exercise group performed the concentric contraction phase of resisted exercise in two seconds. This group performed sit to stand exercise, walking, curbs, stairs, and other exercises at the participant preferred rate.

Behavioral: Exercise

Interventions

Exercise BEHAVIORAL

Participants attended standardized exercise (ex) sessions twice a week for six weeks for 12 sessions. Group speed differed for concentric contractions, sit to stand ex, walking, curbs, and stairs. The low velocity ex group performed a concentric contraction in two seconds, and high velocity group in one second or less. End range concentric hold, eccentric contraction, repetition (rep) rest and set rest were the same. Open chain ex was performed at 50% of one Repetition Maximum (RM) x 10 reps x one set and then 80% of 1RM x 10 reps x two sets. Curb height and 1RM was assessed at the first, fifth and ninth sessions. Manual stretching, balance ex, sit to stand support, level of aerobic ex, gait training, and functional training were assessed and progressed at any session.

Also known as: Rehabilitation

High Velocity Exercise; Low Velocity exercise

Eligibility Criteria

• Age: 60 Years - 89 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults aged 60- 89 years of age.
• primary unilateral TKA 10-21 days prior to the outpatient PT evaluation
• received inpatient rehabilitation at Helen Hayes Hospital

You may not qualify if:

• Any other lower extremity joint or back pain (not inclusive of recent Total knee arthroplasty) rated greater than four out of ten with weight-bearing
• any other lower extremity joint replacement surgery
• diagnosis of osteoporosis with history of fractures, uncontrolled hypertension, unstable cardiac or pulmonary problems, neurological disease affecting motor control, uncontrolled diabetes
• chest pain or shortness of breath on stair-climbing
• requirement of human assistance to walk in addition to the ambulation device
• inability to follow instructions to perform testing and/or exercise,
• participants who stated that they would not be available to complete 12 exercise sessions
• individual adherence with performance of a home exercise program (HEP) less than five of seven days at the end of the treatment period

Sponsors & Collaborators

• Helen Hayes Hospital: lead

Study Sites (1)

Helen Hayes Hospital

West Haverstraw, New York, 10993, United States

Location

MeSH Terms

Conditions

Osteoarthritis, Knee; Motor Activity

Interventions

Exercise; Rehabilitation

Condition Hierarchy (Ancestors)

Osteoarthritis; Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Behavior

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Health Services; Health Care Facilities Workforce and Services

Study Officials

• Marie A. Kelly, DHS

  Helen Hayes Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Primary Investigator

Study Record Dates

• First Submitted: February 26, 2012
• First Posted: March 7, 2012
• Study Start: September 1, 2009
• Primary Completion: December 1, 2011
• Study Completion: December 1, 2011
• Last Updated: March 7, 2012

Record last verified: 2012-03

Locations

US (1)