REASON 1 Trial: Sonography in Cardiac Arrest
1 other identifier
observational
793
2 countries
7
Brief Summary
The aim of this study is to investigate the predictive value of the presence or absence of cardiac activity by bedside ultrasound during cardiac arrest. The investigators anticipate based on previous research that patients who suffer a cardiac arrest and have cardiac activity on bedside ultrasound will have a greater chance of surviving to hospital admission. The investigators hypothesis is that the mortality rate in patients in cardiac arrest with no cardiac activity by ultrasound will have a mortality rate of 100%.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2010
Longer than P75 for all trials
7 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2010
CompletedFirst Submitted
Initial submission to the registry
September 9, 2011
CompletedFirst Posted
Study publicly available on registry
October 5, 2011
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 1, 2014
CompletedStudy Completion
Last participant's last visit for all outcomes
November 1, 2015
CompletedDecember 2, 2015
November 1, 2015
4.8 years
September 9, 2011
November 30, 2015
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Number of patients that survive to Hospital Discharge
Participants will be followed for the duration of hospital stay, an expected average of up to 12 months. The time frame is an estimate based on previous research. Patients could survive hours to days to weeks or months.
Up to 12 months
Secondary Outcomes (2)
The number of patients that demonstrate a Return of Spontaneous Circulation
Up to 60 Minutes -
The number of patients that survive to hospital admission
Up to 24 hours
Study Arms (1)
Cardiac Arrest
Patients in Cardiac Arrest will be enrolled
Eligibility Criteria
Patients in cardiac arrest
You may qualify if:
- Patients in cardiac arrest with no pulse
You may not qualify if:
- Patients with isolated ventricular fibrillation as their cardiac rhythm at the time of presentation
- Traumatic cardiopulmonary arrest
- Ultrasound system or physician experienced in bedside cardiac ultrasound not available
- Resuscitative efforts halted due to end of life decisions or designations
- Attending physician of record declines enrollment of patient
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- University of Massachusetts, Worcesterlead
- North Shore University Hospitalcollaborator
- NYU Langone Healthcollaborator
- Mount Sinai Hospital, New Yorkcollaborator
- Washington University School of Medicinecollaborator
- University of New Mexicocollaborator
- Wake Forest University Health Sciencescollaborator
- University of California, Irvinecollaborator
- University of Utahcollaborator
- Carolinas Medical Centercollaborator
- Emory Universitycollaborator
- Louisiana State University Health Sciences Center in New Orleanscollaborator
- Duke Universitycollaborator
- Brigham and Women's Hospitalcollaborator
- Massachusetts General Hospitalcollaborator
- Rhode Island Hospitalcollaborator
- Christiana Care Health Servicescollaborator
- George Washington Universitycollaborator
- Kingston Health Sciences Centrecollaborator
- University of Ottawacollaborator
- Jewish General Hospitalcollaborator
- Horizon Health Networkcollaborator
- York Hospitalscollaborator
- Boston Medical Centercollaborator
- Indiana Universitycollaborator
- Yale Universitycollaborator
- Queen's Medical Centercollaborator
- University of Hawaiicollaborator
- Stanford Universitycollaborator
Study Sites (7)
Christiana Health Care
Newark, Delaware, 19718, United States
Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
UMASS Memorial Medical Center
Worcester, Massachusetts, 01655, United States
Washington University Hospital
St Louis, Missouri, 63130, United States
Northshore University Hospital
Manhasset, New York, 11030, United States
Carolinas Medical Center
Charlotte, North Carolina, 28203, United States
University of Ottowa
Ottowa, Canada
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Romolo Gaspari, MD, PhD
UMass Memorial Health
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Director, Division of Emergency Ultrsound
Study Record Dates
First Submitted
September 9, 2011
First Posted
October 5, 2011
Study Start
January 1, 2010
Primary Completion
November 1, 2014
Study Completion
November 1, 2015
Last Updated
December 2, 2015
Record last verified: 2015-11