NCT01358318

Brief Summary

The purpose of this study is to determine whether ingestion of a bar containing either added soy protein or soy fiber or both, increases subjective and objective measures of satiety compared to a control bar.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Feb 2011

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2011

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2011

Completed
18 days until next milestone

First Submitted

Initial submission to the registry

May 19, 2011

Completed
4 days until next milestone

First Posted

Study publicly available on registry

May 23, 2011

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2011

Completed
Last Updated

June 7, 2012

Status Verified

June 1, 2012

Enrollment Period

3 months

First QC Date

May 19, 2011

Last Update Submit

June 6, 2012

Conditions

Keywords

obesitysatietysoy proteinsoy fibercontrol appetitereduce food intake

Outcome Measures

Primary Outcomes (1)

  • Satiety

    visual analog scales for satiety

    at each visit (4 visits total)

Secondary Outcomes (1)

  • Ad Libitum Energy Intake

    at each visit (4 visits total)

Study Arms (4)

Control

PLACEBO COMPARATOR
Other: Satiety

Soy Protein

EXPERIMENTAL
Other: Satiety

Soy Fiber

EXPERIMENTAL
Other: Satiety

Soy Protein and Soy Fiber

EXPERIMENTAL
Other: Satiety

Interventions

SatietyOTHER

Single consumption of snack bars to determine satiety and food intake at next meal.

ControlSoy FiberSoy ProteinSoy Protein and Soy Fiber

Eligibility Criteria

Age20 Years - 60 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • BMI between 20 and 30 kg/m2
  • Age between 20-60y
  • Unrestrained eater (score\<15)
  • Regularly consume 3 meals per day
  • Moderate exercise (eg running , aerobics classes, other sports activities) of no more than 7 hours per week

You may not qualify if:

  • use of drugs that influence carbohydrate or lipid metabolism (eg betablockers,hypoglycemic agents, antibiotics taken less than 6 weeks before study entry, glucocorticoids, anti-diarrheal medication, weight loss medication etc), and anti-diabetic medication
  • presence of any significant disease (eg gastrointestinal diseases, diabetes, a CVD event less than 12 weeks from study entry, current hepatic disease etc)
  • use of special dietary treatments or supplement within 4 weeks of study
  • restrained eater (score\>15)
  • weight change (±10% of body weight) within the previous 6 weeks
  • alcohol intake \>2 drinks/day
  • food allergies of any kind
  • swallowing difficulties,
  • exercising more than 7 hours per week

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Glycemic Index Laboratories

Toronto, Ontario, MeC2N8, Canada

Location

MeSH Terms

Conditions

Obesity

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Thomas Wolever, PhD

    Glycemic Index Laboratories, Inc

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
BASIC SCIENCE
Intervention Model
CROSSOVER
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 19, 2011

First Posted

May 23, 2011

Study Start

February 1, 2011

Primary Completion

May 1, 2011

Study Completion

September 1, 2011

Last Updated

June 7, 2012

Record last verified: 2012-06

Locations