Gown and Glove Use to Prevent the Spread of Infection in VA Community Living Centers

NCT01350479 | Completed Results

• 1 other identifier: IIR 10-154
• Study Type: observational
• Target: 203
• Locations: 1 country
• Sites: 7

Brief Summary

Methicillin-resistant S. aureus (MRSA) infections are a common cause of morbidity and mortality in nursing home residents. MRSA is predominantly spread from patient-to-patient by health care workers. The use of gowns, gloves and hand washing prevents this spread; however, their use detracts from a patient-centered, home-like environment which is an important priority for nursing homes. The goal of this project is to determine when it is most important for health care workers to wear gowns and to wash their hands when caring for MRSA colonized Veterans in community living centers.

Conditions

Methicillin-Resistant Staphylococcus Aureus

Keywords

Cross infection; Long term care

Outcome Measures

Primary Outcomes (1)

• MRSA Transmission

  Presence of MRSA on gown or gloves worn by enrolled health care worker for research purposes while providing a specific type of care for enrolled resident

  Will be measured during 6-25 episodes of care interactions scheduled over the 30 days following resident enrollment

Study Arms (2)

MRSA colonized

Residents with history of MRSA in the past year

Not MRSA colonized

Residents without history of MRSA in the past year

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Veterans residing in a participating VA Long Term Care Facility

You may qualify if:

• Resident:
• Age 18 years
• Reside in a participating LTCF for rehabilitation, skilled nursing or maintenance care
• Expected length of stay of \>4 weeks from enrollment
• Written informed consent from participant, or written informed consent from legally authorized representative (LAR) with assent from participant
• Health Care Worker:
• Has direct interaction with participating residents at participating VA Long Term Care Facility (LTCF)
• Verbal informed consent

You may not qualify if:

• Residents:
• None
• Health Care Worker:
• Unable or unwilling to wear protective gown or gloves during healthcare workers (HCW)-resident interaction

Sponsors & Collaborators

• VA Office of Research and Development: lead

Study Sites (7)

Washington DC VA Medical Center, Washington, DC

Washington D.C., District of Columbia, 20422, United States

Location

Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD

Baltimore, Maryland, 21201, United States

Location

Rehabilitation R&D Service, Baltimore, MD

Baltimore, Maryland, 21202, United States

Location

Perry Point VA Medical Center VA Maryland Health Care System, Perry Point, MD

Perry Point, Maryland, 21902, United States

Location

VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA

Boston, Massachusetts, 02130, United States

Location

VA Western New York Healthcare System, Buffalo, NY

Buffalo, New York, 14215, United States

Location

South Texas Health Care System, San Antonio, TX

San Antonio, Texas, 78229, United States

Location

Related Publications (4)

• Pineles L, Morgan DJ, Lydecker A, Johnson JK, Sorkin JD, Langenberg P, Blanco N, Lesse A, Sellick J, Gupta K, Leykum L, Cadena J, Lepcha N, Roghmann MC. Transmission of methicillin-resistant Staphylococcus aureus to health care worker gowns and gloves during care of residents in Veterans Affairs nursing homes. Am J Infect Control. 2017 Sep 1;45(9):947-953. doi: 10.1016/j.ajic.2017.03.004. Epub 2017 Apr 18.

  PMID: 28431853 RESULT

• Jackson SS, Lydecker AD, Magder LS, Roghmann MC. Development and Validation of a Clinical Prediction Rule to Predict Transmission of Methicillin-Resistant Staphylococcus aureus in Nursing Homes. Am J Epidemiol. 2019 Jan 1;188(1):214-221. doi: 10.1093/aje/kwy220.

  PMID: 30351349 DERIVED

• Roghmann MC, Andronescu LR, Stucke EM, Johnson JK. Clostridium difficile Colonization of Nursing Home Residents. Infect Control Hosp Epidemiol. 2017 Oct;38(10):1267-1268. doi: 10.1017/ice.2017.172. Epub 2017 Aug 22. No abstract available.

  PMID: 28826425 DERIVED

• Blanco N, Pineles L, Lydecker AD, Johnson JK, Sorkin JD, Morgan DJ; VA Gown and Glove Investigators; Roghmann MC. Transmission of Resistant Gram-Negative Bacteria to Health Care Worker Gowns and Gloves during Care of Nursing Home Residents in Veterans Affairs Community Living Centers. Antimicrob Agents Chemother. 2017 Sep 22;61(10):e00790-17. doi: 10.1128/AAC.00790-17. Print 2017 Oct.

  PMID: 28717036 DERIVED

Biospecimen

Retention: SAMPLES WITHOUT DNA

Swabs of the gowns and gloves of health care workers that interact with the participants will be tested for MRSA and other types of bacteria. Swabs from body sites (e.g. nose) of participants will be tested for MRSA and other types of bacteria.

MeSH Terms

Conditions

Cross Infection

Condition Hierarchy (Ancestors)

Infections; Iatrogenic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Results Point of Contact

• Title: Mary-Claire Roghmann
• Organization: VA Maryland Healthcare System

mroghman@epi.umaryland.edu

410-706-0062

Study Officials

• Mary-Claire Roghmann, MD

  Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: Yes

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: FED
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 6, 2011
• First Posted: May 9, 2011
• Study Start: October 1, 2012
• Primary Completion: January 15, 2016
• Study Completion: November 1, 2016
• Last Updated: October 5, 2017
• Results First Posted: March 15, 2017

Record last verified: 2017-09

Data Sharing

• IPD Sharing: Will not share

Locations

US (7)