Comparison of Bacterial Contamination Rates Between Isolation and Non-isolation Rooms

NCT01671358 | Completed

• 1 other identifier: WVU-00010
• Study Type: observational
• Target: 400
• Locations: 1 country
• Sites: 1

Brief Summary

This study is to determine if medication cabinets located outside of isolation rooms in hospitals and their contents, particularly medications and the delivery folders are at a higher risk of having harmful bacteria on them.

Conditions

Methicillin-Resistant Staphylococcus Aureus

Keywords

MRSA; Contamination; Isolation

Outcome Measures

Primary Outcomes (1)

• Presence of MRSA colonization

  Swabbing of four areas of the medication cabinet will be performed (keypad, handle, medication folder and a medication). A Semi-quantitative sampling technique will be used to collect the samples. A sterile saline moistened sterile cotton tip swab will be used to swab the specified areas. The swabs will then be used to inoculate sheep blood agar plates in 4 quadrants. The plates will be incubated for 48 hours. The number of quadrants with growth will be identified. Individual colonies will be removed from the plate with an inoculation loop, then streaked onto a second sheep blood agar plate. The second plates will be incubated for 48 hours. The colonies will then be run through standard identification tests to determine if the colonies are MRSA or not. A comparison will be made between non-isolation and isolation rooms.

  Hospital stay, an expected average of 14 days

Secondary Outcomes (1)

• Quantification of MRSA colonization

  Hospital stay, an expected average of 14 days

Other Outcomes (3)

• Presence of other bacterial colonization

  Hospital stay, an expected average of 14 days

• Correlation between MRSA and active infection or colonization of patient

  Hospital stay, an expected average of 14 days

• Correlation between colonization of other positive organisms and active infection or colonization of patient

  Hospital stay, an expected average of 14 days

Study Arms (2)

Isolation Rooms for MRSA

Rooms that currently have a patient in them that are in isolation status due to MRSA

Non-isolation rooms

Rooms that have not been occupied by a patient in isolation due to MRSA for 14 days

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Inaptients at an academic medical center

You may qualify if:

• Patient rooms with isolation status for MRSA
• Patient rooms without isolation status for MRSA for 14 days

You may not qualify if:

• Rooms without medication cabinets directly outside the room

Sponsors & Collaborators

• West Virginia University: lead

Study Sites (1)

West Virginia University Hospitals

Morgantown, West Virginia, 26506, United States

Location

Related Publications (5)

• Bures S, Fishbain JT, Uyehara CF, Parker JM, Berg BW. Computer keyboards and faucet handles as reservoirs of nosocomial pathogens in the intensive care unit. Am J Infect Control. 2000 Dec;28(6):465-71. doi: 10.1067/mic.2000.107267.

  PMID: 11114617 BACKGROUND

• Sexton T, Clarke P, O'Neill E, Dillane T, Humphreys H. Environmental reservoirs of methicillin-resistant Staphylococcus aureus in isolation rooms: correlation with patient isolates and implications for hospital hygiene. J Hosp Infect. 2006 Feb;62(2):187-94. doi: 10.1016/j.jhin.2005.07.017. Epub 2005 Nov 14.

  PMID: 16290319 BACKGROUND

• Oie S, Hosokawa I, Kamiya A. Contamination of room door handles by methicillin-sensitive/methicillin-resistant Staphylococcus aureus. J Hosp Infect. 2002 Jun;51(2):140-3. doi: 10.1053/jhin.2002.1221.

  PMID: 12090803 BACKGROUND

• Huang SS, Datta R, Platt R. Risk of acquiring antibiotic-resistant bacteria from prior room occupants. Arch Intern Med. 2006 Oct 9;166(18):1945-51. doi: 10.1001/archinte.166.18.1945.

  PMID: 17030826 BACKGROUND

• Huang R, Mehta S, Weed D, Price CS. Methicillin-resistant Staphylococcus aureus survival on hospital fomites. Infect Control Hosp Epidemiol. 2006 Nov;27(11):1267-9. doi: 10.1086/507965. Epub 2006 Sep 28.

  PMID: 17080391 BACKGROUND

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Pharmacy Clinical Specialist - Quality Outcomes

Study Record Dates

• First Submitted: August 16, 2012
• First Posted: August 23, 2012
• Study Start: August 1, 2012
• Primary Completion: June 1, 2013
• Study Completion: June 1, 2013
• Last Updated: June 2, 2015

Record last verified: 2015-06

Locations

US (1)