NCT01342783

Brief Summary

RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer. PURPOSE: This research trial is studying biomarkers in samples from young patients with soft tissue sarcoma.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 23, 2011

Completed
4 days until next milestone

First Posted

Study publicly available on registry

April 27, 2011

Completed
4 days until next milestone

Study Start

First participant enrolled

May 1, 2011

Completed
5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2016

Completed
Last Updated

May 18, 2016

Status Verified

May 1, 2016

Enrollment Period

5 years

First QC Date

April 23, 2011

Last Update Submit

May 17, 2016

Conditions

Sarcoma

Keywords

metastatic childhood soft tissue sarcomanonmetastatic childhood soft tissue sarcomarecurrent childhood soft tissue sarcomapreviously treated childhood rhabdomyosarcomapreviously untreated childhood rhabdomyosarcomarecurrent childhood rhabdomyosarcoma

Outcome Measures

Primary Outcomes (1)

  • Occurrence of somatic mutations in driver genes and mutations in other genes that occur individually

Interventions

DNA analysisGENETIC
RNA analysisGENETIC
mutation analysisGENETIC
nucleic acid sequencingGENETIC
laboratory biomarker analysisOTHER

Eligibility Criteria

AgeUp to 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodNon-Probability Sample
Study Population

COG-D9902 soft tissue sarcoma biology and banking study participants.

DISEASE CHARACTERISTICS: * Banked childhood samples from the COG-D9902 soft tissue sarcoma biology and banking study * Rhabdomyosarcoma, NOS PATIENT CHARACTERISTICS: * Not specified PRIOR CONCURRENT THERAPY: * Not specified

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

MeSH Terms

Conditions

Sarcoma

Interventions

Base Sequence

Condition Hierarchy (Ancestors)

Neoplasms, Connective and Soft TissueNeoplasms by Histologic TypeNeoplasms

Intervention Hierarchy (Ancestors)

Molecular StructureBiochemical PhenomenaChemical PhenomenaGenetic StructuresGenetic Phenomena

Study Officials

  • Poul Sorensen, MD, PhD

    British Columbia Cancer Agency

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
RETROSPECTIVE
Sponsor Type
NETWORK
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 23, 2011

First Posted

April 27, 2011

Study Start

May 1, 2011

Primary Completion

May 1, 2016

Last Updated

May 18, 2016

Record last verified: 2016-05