Effects of Aerobic Training in End Stage Renal Disease Patients

NCT01234688 | Completed DMC

• 1 other identifier: 001
• Study Type: interventional
• Target: 28
• Locations: 1 country
• Sites: 1

Brief Summary

The investigators raised the hypothesis that exercise training would be associated with improvement in exercise tolerance and VO2 kinetics in hemodialysis patients.

Conditions

Kidney Failure, Chronic

Keywords

Exercise Tolerance; Physical Endurance

Outcome Measures

Primary Outcomes (1)

• Effects of aerobic training during hemodialysis on exercise tolerance and VO2 kinetics in end stage renal disease patients

  Before and after the intervention or control periods, the participants were submitted to an incremental work rate test and, two days apart, to a constant work rate test to the limit of tolerance.

  3 months

Study Arms (2)

Exercise training

EXPERIMENTAL

Patients included in the exercise group were submitted to intra-dialytic exercise training, 3 times per week for 12 weeks.

Other: Exercise training

Control

NO INTERVENTION

Patients allocated to the control group remained in regular dialysis treatment during the same timeframe.

Interventions

Exercise training OTHER

Patients included in the exercise group were submitted to intra-dialytic exercise training, 3 times per week for 12 weeks.

Also known as: Exercise group

Exercise training

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• The sample included end stage renal disease patients undergoing hemodialysis, three times per week totaling 12h weekly, for at least 6 months in the Nephrology Unit at the University Hospital of the Federal University of Juiz de Fora, State of Minas Gerais, Brazil. No patient had been involved in any kind of exercise training in the preceding 6 months

You may not qualify if:

• unstable angina;
• uncontrolled arrhythmia;
• uncompensated heart failure;
• uncontrolled hypertension (systolic blood pressure ≥ 200 mmHg and/or diastolic blood pressure ≥ 120 mmHg);
• diabetes mellitus;
• severe respiratory diseases;
• acute infection;
• severe renal osteodystrophy;
• neurological or musculoskeletal disturbances

Sponsors & Collaborators

• Federal University of Juiz de Fora: lead

Study Sites (1)

Federal University of Juiz de Fora-Núcleo Interdisciplinar de Estudos e Pesquisas em Nefrologia (NIEPEN)

Juiz de Fora, Minas Gerais, 36036-330, Brazil

Location

Related Publications (3)

• Bernier-Jean A, Beruni NA, Bondonno NP, Williams G, Teixeira-Pinto A, Craig JC, Wong G. Exercise training for adults undergoing maintenance dialysis. Cochrane Database Syst Rev. 2022 Jan 12;1(1):CD014653. doi: 10.1002/14651858.CD014653.

  PMID: 35018639 DERIVED

• Reboredo MM, Neder JA, Pinheiro BV, Henrique DM, Lovisi JC, Paula RB. Intra-dialytic training accelerates oxygen uptake kinetics in hemodialysis patients. Eur J Prev Cardiol. 2015 Jul;22(7):912-9. doi: 10.1177/2047487314543079. Epub 2014 Jul 18.

  PMID: 25038079 DERIVED

• Reboredo MM, Neder JA, Pinheiro BV, Henrique DM, Faria RS, Paula RB. Constant work-rate test to assess the effects of intradialytic aerobic training in mildly impaired patients with end-stage renal disease: a randomized controlled trial. Arch Phys Med Rehabil. 2011 Dec;92(12):2018-24. doi: 10.1016/j.apmr.2011.07.190.

  PMID: 22133251 DERIVED

MeSH Terms

Conditions

Kidney Failure, Chronic

Interventions

Exercise

Condition Hierarchy (Ancestors)

Renal Insufficiency, Chronic; Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Maycon M Reboredo, DSc

  Federal University of Juiz de Fora

  PRINCIPAL INVESTIGATOR

• Rogério B de Paula, DSc

  Federal University of Juiz de Fora

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: November 3, 2010
• First Posted: November 4, 2010
• Study Start: June 1, 2008
• Primary Completion: June 1, 2010
• Study Completion: June 1, 2010
• Last Updated: November 4, 2010

Record last verified: 2010-07

Locations

BR (1)