The Effect of 16 Weeks of Hip Adduction and Abduction Resistance Exercise

NCT01228877 | Completed

• 1 other identifier: Ad/Ab exercise
• Study Type: interventional
• Target: 22
• Locations: 1 country
• Sites: 1

Brief Summary

Performing adduction and abduction resistance exercise will increase hip bone density and strength to a greater extent than doing squat and deadlift exercise. Aim #1: To determine if doing hip adduction and abduction resistance exercise training for 16 weeks improves spine bone mineral density and hip bone mineral density and strength as determined by finite element modeling. Aim #2: To compare the effects of hip adduction and abduction exercise to squat and deadlift exercise with respect to potential changes in hip bone mineral density and strength. Aim #3: To determine if the addition of adduction and abduction exercise to squat and deadlift exercise promotes an "additive" effect with respect to changes in spine bone mineral density and hip bone mineral density and bone strength.

Conditions

Osteoporosis; Osteopenia; Sarcopenia

Outcome Measures

Primary Outcomes (1)

• Reduce risk of hip fracture

  The investigators have prioritized the last year of NSBRI funding to test one the capabilities of our device, standing hip adduction/abduction exercise, to strengthen the proximal femoral bone. We believe that if we are able to detect increases in bone density and strength (assessed using quantitative computed tomography of the hip pre- and post-training) in healthy volunteers, this will be solid preliminary evidence to support modification of exercise protocols currently being used to reduce the rate of bone loss on the International Space Station.

  16 weeks

Study Arms (1)

Exercise

EXPERIMENTAL

Adduction, Abduction and Squat exercise three times a week for 16 weeks

Other: exercise

Interventions

exercise OTHER

Adduction, Abduction and Squat exercise three times a week for 16 weeks

Exercise

Eligibility Criteria

• Age: 25 Years - 55 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Healthy men and women
• Age of 25 to 55 years old

You may not qualify if:

• Hypertension (High blood pressure)
• Diabetes or metabolic syndrome
• Hyperlipidemia (High cholesterol)
• Cardiovascular Disease
• Asthma or other pulmonary disease (i.e. COPD)
• not pregnant
• have no joint or mobility limitations
• do not exercise on a regular basis

Sponsors & Collaborators

• University of California, San Francisco: lead
• National Space Biomedical Research Institute: collaborator

Study Sites (1)

UCSF-Department of radiology-China Basin

San Francisco, California, 94107, United States

Location

MeSH Terms

Conditions

Osteoporosis; Bone Diseases, Metabolic; Sarcopenia

Interventions

Exercise

Condition Hierarchy (Ancestors)

Bone Diseases; Musculoskeletal Diseases; Metabolic Diseases; Nutritional and Metabolic Diseases; Muscular Atrophy; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Atrophy; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Signs and Symptoms

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Thomas Lang, PhD

  UCSF-Department of Radiology

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 8, 2010
• First Posted: October 27, 2010
• Study Start: December 1, 2010
• Primary Completion: June 1, 2012
• Study Completion: September 1, 2012
• Last Updated: October 27, 2017

Record last verified: 2017-10

Locations

US (1)