NCT01133093

Brief Summary

The purpose of this study is to assess the distribution, awareness and control of main cardiovascular risk factors in the Spanish population. The main study variables are:

  • Lifestyles (tobacco, alcohol, nutrition, physical activity)
  • Biological risk factors either well-established (blood lipids, glucose, insulin and blood pressure) or emergent (leptin, C-reactive protein and other markers of inflammation)

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
11,991

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Mar 2008

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2008

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2008

Completed
2 years until next milestone

First Submitted

Initial submission to the registry

May 27, 2010

Completed
1 day until next milestone

First Posted

Study publicly available on registry

May 28, 2010

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2010

Completed
Last Updated

May 6, 2016

Status Verified

May 1, 2016

Enrollment Period

3 months

First QC Date

May 27, 2010

Last Update Submit

May 5, 2016

Conditions

Cardiovascular Disease

Keywords

Cardiovascular risk factorsNutritional assessmentEpidemiology

Outcome Measures

Primary Outcomes (3)

  • Cardiovascular Risk Factors Control

    2 years

  • Health-related quality of life

    2 years

  • Use of health care services

    2 years

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Community sample representative of the non-institutionalized Spanish population

You may qualify if:

  • Non-institutionalized Spanish resident
  • years and over

You may not qualify if:

  • None

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Preventive Medicine and Public Health. Universidad Autonoma de Madrid

Madrid, Madrid, 28029, Spain

Location

Related Publications (16)

  • Gutierrez-Fisac JL, Guallar-Castillon P, Leon-Munoz LM, Graciani A, Banegas JR, Rodriguez-Artalejo F. Prevalence of general and abdominal obesity in the adult population of Spain, 2008-2010: the ENRICA study. Obes Rev. 2012 Apr;13(4):388-92. doi: 10.1111/j.1467-789X.2011.00964.x. Epub 2011 Dec 12.

    PMID: 22151906RESULT

  • Guallar-Castillon P, Gil-Montero M, Leon-Munoz LM, Graciani A, Bayan-Bravo A, Taboada JM, Banegas JR, Rodriguez-Artalejo F. Magnitude and management of hypercholesterolemia in the adult population of Spain, 2008-2010: The ENRICA Study. Rev Esp Cardiol (Engl Ed). 2012 Jun;65(6):551-8. doi: 10.1016/j.recesp.2012.02.005. Epub 2012 Apr 5.

    PMID: 22483404RESULT

  • Leon-Munoz LM, Guallar-Castillon P, Graciani A, Lopez-Garcia E, Mesas AE, Aguilera MT, Banegas JR, Rodriguez-Artalejo F. Adherence to the Mediterranean diet pattern has declined in Spanish adults. J Nutr. 2012 Oct;142(10):1843-50. doi: 10.3945/jn.112.164616. Epub 2012 Aug 8.

    PMID: 22875552RESULT

  • Banegas JR, Graciani A, de la Cruz-Troca JJ, Leon-Munoz LM, Guallar-Castillon P, Coca A, Ruilope LM, Rodriguez-Artalejo F. Achievement of cardiometabolic goals in aware hypertensive patients in Spain: a nationwide population-based study. Hypertension. 2012 Oct;60(4):898-905. doi: 10.1161/HYPERTENSIONAHA.112.193078. Epub 2012 Sep 4.

    PMID: 22949530RESULT

  • Mesas AE, Leon-Munoz LM, Guallar-Castillon P, Graciani A, Gutierrez-Fisac JL, Lopez-Garcia E, Aguilera MT, Banegas JR, Rodriguez-Artalejo F. Obesity-related eating behaviours in the adult population of Spain, 2008-2010. Obes Rev. 2012 Oct;13(10):858-67. doi: 10.1111/j.1467-789X.2012.01005.x. Epub 2012 May 11.

    PMID: 22577840RESULT

  • Lundelin K, Graciani A, Garcia-Puig J, Guallar-Castillon P, Taboada JM, Rodriguez-Artalejo F, Banegas JR. Knowledge of stroke warning symptoms and intended action in response to stroke in Spain: a nationwide population-based study. Cerebrovasc Dis. 2012;34(2):161-8. doi: 10.1159/000341408. Epub 2012 Aug 17.

    PMID: 22907330RESULT

  • Navarro-Vidal B, Banegas JR, Leon-Munoz LM, Rodriguez-Artalejo F, Graciani A. Achievement of cardiometabolic goals among diabetic patients in Spain. A nationwide population-based study. PLoS One. 2013 Apr 18;8(4):e61549. doi: 10.1371/journal.pone.0061549. Print 2013.

    PMID: 23637851RESULT

  • Graciani A, Leon-Munoz LM, Guallar-Castillon P, Rodriguez-Artalejo F, Banegas JR. Cardiovascular health in a southern Mediterranean European country: a nationwide population-based study. Circ Cardiovasc Qual Outcomes. 2013 Jan 1;6(1):90-8. doi: 10.1161/CIRCOUTCOMES.112.967893. Epub 2013 Jan 8.

    PMID: 23300271RESULT

  • Lopez-Garcia E, Guallar-Castillon P, Leon-Munoz L, Rodriguez-Artalejo F. Prevalence and determinants of metabolically healthy obesity in Spain. Atherosclerosis. 2013 Nov;231(1):152-7. doi: 10.1016/j.atherosclerosis.2013.09.003. Epub 2013 Sep 18.

    PMID: 24125427RESULT

  • Soler-Vila H, Galan I, Valencia-Martin JL, Leon-Munoz LM, Guallar-Castillon P, Rodriguez-Artalejo F. Binge drinking in Spain, 2008-2010. Alcohol Clin Exp Res. 2014 Mar;38(3):810-9. doi: 10.1111/acer.12275. Epub 2013 Oct 24.

    PMID: 24164355RESULT

  • Graciani A, Rodriguez-Artalejo F, Navarro-Vidal B, Banegas JR. Glycemic control using individualized targets among diabetic patients in Spain: a population-based study. Rev Esp Cardiol (Engl Ed). 2014 Feb;67(2):151-3. doi: 10.1016/j.rec.2013.07.018. Epub 2013 Dec 4. No abstract available.

    PMID: 24795130RESULT

  • Guallar-Castillon P, Perez RF, Lopez Garcia E, Leon-Munoz LM, Aguilera MT, Graciani A, Gutierrez-Fisac JL, Banegas JR, Rodriguez-Artalejo F. Magnitude and management of metabolic syndrome in Spain in 2008-2010: the ENRICA study. Rev Esp Cardiol (Engl Ed). 2014 May;67(5):367-73. doi: 10.1016/j.rec.2013.08.014. Epub 2014 Jan 14.

    PMID: 24774729RESULT

  • Leon-Munoz LM, Galan I, Donado-Campos J, Sanchez-Alonso F, Lopez-Garcia E, Valencia-Martin JL, Guallar-Castillon P, Rodriguez-Artalejo F. Patterns of alcohol consumption in the older population of Spain, 2008-2010. J Acad Nutr Diet. 2015 Feb;115(2):213-224. doi: 10.1016/j.jand.2014.08.017. Epub 2014 Oct 5.

    PMID: 25288520RESULT

  • Blanco-Rojo R, Sandoval-Insausti H, Lopez-Garcia E, Graciani A, Ordovas JM, Banegas JR, Rodriguez-Artalejo F, Guallar-Castillon P. Consumption of Ultra-Processed Foods and Mortality: A National Prospective Cohort in Spain. Mayo Clin Proc. 2019 Nov;94(11):2178-2188. doi: 10.1016/j.mayocp.2019.03.035. Epub 2019 Oct 14.

    PMID: 31623843DERIVED

  • Laclaustra M, Rodriguez-Artalejo F, Guallar-Castillon P, Banegas JR, Graciani A, Garcia-Esquinas E, Lopez-Garcia E. The inflammatory potential of diet is related to incident frailty and slow walking in older adults. Clin Nutr. 2020 Jan;39(1):185-191. doi: 10.1016/j.clnu.2019.01.013. Epub 2019 Jan 24.

    PMID: 30737049DERIVED

  • Rodriguez-Artalejo F, Graciani A, Guallar-Castillon P, Leon-Munoz LM, Zuluaga MC, Lopez-Garcia E, Gutierrez-Fisac JL, Taboada JM, Aguilera MT, Regidor E, Villar-Alvarez F, Banegas JR. [Rationale and methods of the study on nutrition and cardiovascular risk in Spain (ENRICA)]. Rev Esp Cardiol. 2011 Oct;64(10):876-82. doi: 10.1016/j.recesp.2011.05.019. Epub 2011 Aug 6. Spanish.

    PMID: 21821340DERIVED

Biospecimen

Retention: SAMPLES WITHOUT DNA

Blood and urine samples

MeSH Terms

Conditions

Cardiovascular Diseases

Study Officials

  • Jose R Banegas, MD, PhD

    Department of Preventive Medicine and Public Health, Universidad Autonoma de Madrid

    PRINCIPAL INVESTIGATOR

  • Fernando Rodriguez-Artalejo, MD, PhD

    Department of Preventive Medicine and Public Health, Universidad Autonoma de Madrid

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor of Preventive Medicine and Public Health

Study Record Dates

First Submitted

May 27, 2010

First Posted

May 28, 2010

Study Start

March 1, 2008

Primary Completion

June 1, 2008

Study Completion

October 1, 2010

Last Updated

May 6, 2016

Record last verified: 2016-05

Locations

ES(1)