Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 40/100

Failure Rate

14.2%

325 terminated/withdrawn out of 2295 trials

Success Rate

83.5%

-3.0% vs industry average

Late-Stage Pipeline

46%

1046 trials in Phase 3/4

Results Transparency

32%

525 of 1644 completed trials have results

Key Signals

134 recruiting525 with results278 terminated47 withdrawn

Enrollment Performance

Analytics

Phase 3
685(32.7%)
Phase 2
584(27.9%)
Phase 1
382(18.3%)
Phase 4
361(17.2%)
N/A
81(3.9%)
2093Total
Phase 3(685)
Phase 2(584)
Phase 1(382)
Phase 4(361)
+1 more

Activity Timeline

Global Presence

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Clinical Trials (2295)

Showing 20 of 2295 trials
NCT06676319Phase 2Recruiting

Study of Lunsekimig (SAR443765) Compared With Placebo in Adults With High-risk Asthma

Role: lead

NCT06290141Phase 3Recruiting

A Study to Test the Efficacy and Safety of Riliprubart Against the Usual Treatment of Intravenous Immunoglobulin (IVIg) in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Role: lead

NCT05097287Phase 4Active Not Recruiting

Study Assessing the Long-term Effect of Dupilumab on Prevention of Lung Function Decline in Adult Patients With Uncontrolled Moderate to Severe Asthma

Role: lead

NCT07133425Phase 2Recruiting

A Phase 2 Platform Study of Immunomodulatory Compounds in ICI-refractory Non-small Cell Lung Cancer

Role: collaborator

NCT07285460Phase 3Recruiting

A Study to Investigate the Efficacy and Safety of Fitusiran Prophylaxis in Male Participants Aged 1 to Less Than 12 Years With Hemophilia A or B

Role: lead

NCT06859099Phase 3Enrolling By Invitation

Long-term Safety and Efficacy Study of Riliprubart in Participants With CIDP

Role: lead

NCT04701983Phase 3Completed

Study to Assess the Efficacy, Safety, and Tolerability of SAR440340/REGN3500/Itepekimab in Chronic Obstructive Pulmonary Disease (COPD)

Role: lead

NCT07247188Phase 3Recruiting

Study of a Single Dose of a 21-valent Pneumococcal Conjugate Vaccine in Children and Adolescents With Sickle Cell Disease

Role: lead

NCT05153772Phase 2Active Not Recruiting

Targeted Alpha-emitter Therapy of PRRT Naïve and Previous PRRT Neuroendocrine Tumor Patients

Role: collaborator

NCT04751487Phase 3Completed

Study to Assess the Efficacy, Safety, and Tolerability of SAR440340/REGN3500/Itepekimab in Chronic Obstructive Pulmonary Disease (COPD)

Role: lead

NCT07380711Recruiting

Long-term Real-world Study of Dupilumab in COPD : Patient Characteristics, Safety and Patient-reported Outcomes

Role: lead

NCT07088068Phase 3Recruiting

A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes

Role: lead

NCT06914908Phase 2Recruiting

Long-term Safety and Efficacy Evaluation of Lunsekimig in Adult Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) Who Completed a Previous Lunsekimig CRSwNP Study

Role: lead

NCT07316114Recruiting

A Study to Describe the Real-world Effectiveness, Safety and Patterns of Use of Dupilumab in Patients With Chronic Spontaneous Urticaria

Role: lead

NCT06837454Recruiting

French Prospective Observational Study in Patients Eligible for Systemic Therapy for Atopic Dermatitis (AD)

Role: lead

NCT00265642Phase 3Completed

Evaluation of Irbesartan on Hepatic Fibrosis in Chronic Hepatitis C

Role: collaborator

NCT07424144Phase 3Enrolling By Invitation

An Extension Study to Investigate the Long-term Safety and Tolerability of Itepekimab in Adult Participants With Inadequately Controlled Chronic Rhinosinusitis With Nasal Polyps

Role: lead

NCT06290128Phase 3Recruiting

A Study to Test the Effects and Safety of Riliprubart in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) for Which the Usual Treatments do Not Work

Role: lead

NCT05492578Phase 2Enrolling By Invitation

Long-Term Safety and Efficacy Evaluation of Amlitelimab in Participants of Previous Amlitelimab Moderate to Severe Atopic Dermatitis Clinical Trials

Role: lead

NCT06949358Phase 2Completed

A Study to Evaluate Safety and Tolerability of Olipudase Alfa in Pediatric and Adult Participants With Acid Sphingomyelinase Deficiency (ASMD) Who Completed the DFI12712 or the LTS13632 Study in France

Role: lead