Cyanoacrylate and Laser and Dentin Sensitivity

NCT01111474 | Completed Results DMC

• 1 other identifier: odf2008
• Study Type: interventional
• Target: 62
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study aimed to evaluate the effectiveness of two treatments for dental hypersensitivity: cyanoacrylate (Super Bonder®) compared with use of low intensity laser treatment (LILT). As the cyanoacrylate is a lower cost treatment, the hypothesis in investigation is if this product is equally effective as the laser treatment.

Conditions

Dentin Hypersensitivity; Dentin Sensitivity

Keywords

dentin hypersensitivity; cyanoacrylate; laser

Outcome Measures

Primary Outcomes (1)

• Change of the Pain Sensitivity

  Change in pain experienced by the participants was calculated as the difference between baseline level of pain sensitivity and after 180 days. Pain was recorded using a numerical pain assessment scale with range between 0 (no pain) to 10 (worst possible pain). The higher the numbering the worse the result.

  Baseline and 180 days

Secondary Outcomes (1)

• Quality of Life Improvement

  Baseline and 180 days

Study Arms (2)

Cyanoacrylate

ACTIVE COMPARATOR

3 applications of cyanoacrylate (48 hours interval)at the cervical region of the sensitive tooth

Other: Cyanoacrylate

Laser

ACTIVE COMPARATOR

3 Low intensity laser application (48 hour interval). The application of 1Joule/cm\^2 was performed for eight seconds at three points along the dental neck, using the infrared wavelength (795nm)

Radiation: Laser

Interventions

Cyanoacrylate OTHER

3 applications of cyanoacrylate (48 hours interval) at the cervical region of the sensitive tooth

Also known as: Superbonder

Cyanoacrylate

Laser RADIATION

This process was conducted three times with an interval of 48 hours between applications, according to laser's manufacturer advice Clean Line Easy Laser - LILT®, Clean Line Easy Laser Doctor Dental Products Industry LTDA, BRA). For dentin hypersensitivity, the application of 1Joule/cm\^2 is recommended for eight seconds at three points along the dental neck, using the infrared wavelength (795nm).

Also known as: LILT

Laser

Eligibility Criteria

• Age: 12 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• patients should be in good general and dental health;
• present complaints of dental sensitivity to cold, sweet, acidic foods and brushing;
• present complaints of pain in teeth located in different quadrants;
• manifest pain or discomfort upon application of the triple syringe air jet;
• not be in current use of desensitizing agents.

You may not qualify if:

• presence of extensive restorations and carious lesions in the sensitive teeth;
• undergoing orthodontic treatment;
• frequent use of analgesics, antidepressants and anti-inflammatory drugs;
• presence of gingival inflammation;
• non-consent of patient.

Sponsors & Collaborators

• Federal University of São Paulo: lead
• Federal University of the Valleys of Jequitinhonha and Mucuri: collaborator

MeSH Terms

Conditions

Dentin Sensitivity

Interventions

Cyanoacrylates; Lasers

Condition Hierarchy (Ancestors)

Tooth Diseases; Stomatognathic Diseases

Intervention Hierarchy (Ancestors)

Acrylates; Acids, Acyclic; Carboxylic Acids; Organic Chemicals; Nitriles; Polymers; Macromolecular Substances; Biomedical and Dental Materials; Tissue Adhesives; Manufactured Materials; Technology, Industry, and Agriculture; Optical Devices; Equipment and Supplies; Radiation Equipment and Supplies

Results Point of Contact

• Title: Dr. Olga Dumont Flecha - PHD student
• Organization: Federal University of São Paulo

olgaflecha@gmail.com

38 35326082

Study Officials

• Olga D. Flecha, pHD student

  UNIFESP - Federal University of São Paulo, Brazil

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: No
• Restrictive Agreement: No

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PHD student

Study Record Dates

• First Submitted: April 20, 2010
• First Posted: April 27, 2010
• Study Start: August 1, 2008
• Primary Completion: December 1, 2008
• Study Completion: February 1, 2009
• Last Updated: August 17, 2020
• Results First Posted: August 17, 2020

Record last verified: 2020-08