Dentin Hypersensitivity - Varnish or Laser?

NCT06539286 | Not Yet Recruiting

• 1 other identifier: DH
• Study Type: interventional
• Target: 80
• Locations: 0 countries
• Sites: N/A

Brief Summary

Dentin hypersensitivity is a common condition described as a short and sharp pain caused by thermal, evaporative, tactile, osmotic, or chemical stimuli to exposed dentin that cannot be related to another defect or dental pathology. The variety of treatment options and products on the market might seem overwhelming. This study aims to show that laser treatments are efficient in reducing pain scores compared to a desensitizing agent (Gluma). 80 patients with at least two hypersensitive teeth will be enrolled in this study. Patients will be divided randomly into four groups (control group (Gluma), laser group 1 (2.94 µm wavelength), laser group 2 (1064 nm wavelength), laser group 3 (970 nm wavelength)). Visual Analog Scale will be measured before treatment, right after treatment, one week after treatment, one month after treatment, three months after treatment. Mixed Anova's and descriptive analysis will be used for statistical evaluation.

Conditions

Dentin Hypersensitivity

Outcome Measures

Primary Outcomes (1)

• Visual Analog Scale changes

  Patients will rate pain score with VAS. Pain scores will be evaluated before treatment, right after treatment, one week later, one month later and three months later

  three months

Study Arms (4)

Control

ACTIVE COMPARATOR

Desensitizing Agent Gluma

Device: Laser Irradiation

1. Laser Group

ACTIVE COMPARATOR

Er:YAG laser

Device: Laser Irradiation

2. Laser Group

ACTIVE COMPARATOR

Nd:YAG laser

Device: Laser Irradiation

3. Laser Group

ACTIVE COMPARATOR

970 nm diode laser

Device: Laser Irradiation

Interventions

Laser Irradiation DEVICE

three different laser wavelengths will be used

Also known as: Desensitizing Agent Gluma

1. Laser Group; 2. Laser Group; 3. Laser Group; Control

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• all genders
• years
• good general health
• at least two hypersensitive teeth in either jaw
• initial VAS-score \>3

You may not qualify if:

• Active carious lesions, insufficient restorations, enamel cracks, reversible pulpitis
• Active periodontal disease, periodontal surgery (in the last 6 months)
• Bleaching procedure in the last 3 months
• Analgetic use in the last 72 hours
• Pregnant/lactating women

Sponsors & Collaborators

• Sigmund Freud PrivatUniversitat: lead

MeSH Terms

Conditions

Dentin Sensitivity

Interventions

Low-Level Light Therapy

Condition Hierarchy (Ancestors)

Tooth Diseases; Stomatognathic Diseases

Intervention Hierarchy (Ancestors)

Laser Therapy; Therapeutics; Phototherapy

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Masking Details: Patients will not know which laser will be used in the treatment group.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 1, 2024
• First Posted: August 6, 2024
• Study Start: September 2, 2024
• Primary Completion: October 14, 2024
• Study Completion: December 14, 2024
• Last Updated: August 6, 2024

Record last verified: 2024-08