NCT01110278|Completed
Examining Bladder Control Using Magnetic Resonance Imaging (MRI) and Diffusion Tensor Imaging (DTI)
Examining the Brain's Control Systems in Normal and Overactive Bladder Using DTI and Functional MRI
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Examining the Brain's Control Systems in Normal and Overactive Bladder Using DTI and Functional MRI
Sponsor study identifier
observational
47
1 country
1
Study Start
May 2010
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
June 22, 2012
Actual (reported)Study Completion
June 22, 2012
Actual (reported)Urgency incontinence (where the bladder muscles contract suddenly, causing an immediate urge to urinate that is difficult to prevent) is commonly experienced in patients with overactive bladder. New findings have discovered that urgency incontinence may be connected to the interactions of certain regions of the brain and the bladder. Although this is a common problem, researchers still do not know how these interactions impact the process of urgency incontinence. The purpose of this study is to better understand how the brain functions, by using Magnetic Resonance Imaging (MRI) machine and Diffusion Tensor Imaging (DTI) to create images of the brain during different bladder states.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
June 22, 2012
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
April 16, 2010
Actual (reported)April 26, 2010
Actual (reported)May 2010
Date type not reportedThis date has not been verified as actual or estimated.
June 22, 2012
Actual (reported)June 22, 2012
Actual (reported)Determine differences in fluctuations in brain activity between different regions of the brain associated with control functions.
We will look at the overall group differences to see if there are differences between the case group participants and control group participants in control brain regions related to normal bladder function.
Once during up to 3 months
Scores on the Pelvic Floor Distress Inventory
Once during up to 3 months
3 Day Bladder Diary to Assess Participant Symptom Severity
Once during up to 3 months
Determine any difference in brain response to bladder filling in subjects with and without overactive bladder.
Once during up to 3 months
Determine functional brain connectivity with bladder.
Once during up to 3 months
Scores on the Pelvic Floor Impact Questionnaire
Once during up to 3 months
Women with documented urge/urgency incontinence with established care at the Oregon Health and Science University.
Women with no urge/urgency incontinence with established care at the Oregon Health and Science University.
Women seeking care at Oregon Health and Science University in Portland, Oregon.
Oregon Health & Science University
Portland, Oregon, 97239, United States
Rahel Nardos, M.D.
Oregon Health and Science University
47 participants (actual enrollment reported by the registry).
First Submitted
April 16, 2010
First Posted
April 26, 2010
Study Start
May 2010
Date type not reportedThis date has not been verified as actual or estimated.
Brain-Centered Therapy Versus Medication for Urgency Urinary Incontinence : Hypnotherapy Or Pharmacotherapy
Contact the study team to confirm eligibility.
Primary Completion
June 22, 2012
Actual (reported)Study Completion
June 22, 2012
Actual (reported)Last Updated
August 22, 2017
Record last verified: 2017-08
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Source: ClinicalTrials.gov.
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