NCT01073878

Brief Summary

The purpose of this study is to determine if the Athena Pelvic Muscle Trainer device effectively treats stress, urge or mixed incontinence in women by strengthening the pelvic floor muscles by collecting data from the patient on the

  1. 1.Over Active Bladder Questionnaire
  2. 2.The 7-Day Urine Diary questionnaire
  3. 3.Female Sexual Function Index questionnaire

Trial Health

90
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
462

participants targeted

Target at P75+ for phase_4

Timeline
Completed

Started Feb 2010

Geographic Reach
2 countries

97 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2010

Completed
16 days until next milestone

First Submitted

Initial submission to the registry

February 17, 2010

Completed
6 days until next milestone

First Posted

Study publicly available on registry

February 23, 2010

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2011

Completed
Last Updated

July 14, 2011

Status Verified

July 1, 2011

Enrollment Period

1.3 years

First QC Date

February 17, 2010

Last Update Submit

July 13, 2011

Conditions

Keywords

Urinary Urge IncontinenceUrinary Stress IncontinenceUrinary Mixed Incontinence

Outcome Measures

Primary Outcomes (1)

  • To assess objective treatment outcomes of urge, stress or mixed incontinence.

    Outcomes will be measured via patient questionnaires over a 13 week trial. Visit 1 (Week -1) and Visit 4 (Week 12) values for the Overactive Bladder Questionnaire and the Female Sexual Function Index will be captured. 7-day Urine Diaries will be captured for the week preceeding visits 2, 3 and 4.

    5 Visits over 13 weeks. Subjects are seen in the office at Screening Visit 1 (Week -1), Visit 1a (Week 0), Visit 2 (Week 2), Visit 3 (Week 6), Visit 4 (Week 12)

Secondary Outcomes (1)

  • Evaluate effectiveness, tolerability, satisfaction and compliance of the Athena PMT across a wide demographic population using: 1) the Subject Satisfaction Evaluation questionnaire

    At Visit 4 (Week 12)

Interventions

The Athena PMT is a vaginally inserted electrical stimulator that induces the pelvic floor muscles to contract and relax, similar to Kegel exercises intended to strengthen the pelvic floor muscles.

Also known as: Athena PMT, PMT, Pelvic Muscle Trainer, Athena

Eligibility Criteria

Age30 Years - 70 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Women between the ages of 30 and 70 years
  • Suffer from urge-incontinence, stress incontinence or incontinence of mixed etiology and who may benefit from strengthening Kegel muscles by electrical stimulation
  • Able to provide informed consent and physically able to comply with protocol requirements.
  • Experience one or more incontinence episodes per week.
  • Women of childbearing potential must have a negative urine or blood pregnancy test within 7 days prior to initiation of treatment.
  • Subject may be post-menopausal, surgically sterilized, or willing to use acceptable methods of birth control (e.g., hormonal contraceptive, intra- uterine device (IUD), diaphragm with spermicide, condom with spermicide or abstinence) from the screening visit through the duration of study participation.
  • Have a positive response to two or more questions on the Athena Questionnaire

You may not qualify if:

  • Neurological deficiency that does not permit proper sensory perception or stimulation.
  • Is currently pregnant, lactating or attempting to get pregnant
  • Has a cardiac pacemaker or a history of rate or conductive disturbance
  • Has anatomical vaginal structures that do not permit proper and complete placement of the trainer.
  • Has irregular menstrual bleeding cycles.
  • Has urinary or vaginal infections, localized lesions, or other undiagnosed symptoms.
  • Has a history or symptoms of urinary retention.
  • Has cancer or a life expectancy of less than one year
  • Recreational drug use
  • Consume more than three caffeine beverages daily
  • Consume more than 1-2 alcoholic drinks per day
  • Significant drug use (causing diuresis or urinary retention
  • Allergy or sensitivity to materials in the Athena PMT
  • Participation in another clinical trial within past 3 months
  • Subjects morbidly obese (BMI \>35)
  • +5 more criteria

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (97)

John Foster MD

Birmingham, Alabama, 35205, United States

Location

La Mamma Spa

Birmingham, Alabama, 35211, United States

Location

Kyle Chavers MD

Dothan, Alabama, 36305, United States

Location

Salud! for Women

Casa Grande, Arizona, 85122, United States

Location

New Horizons Women's Care

Chandler, Arizona, 85226, United States

Location

Barbara Wiggin PhD, ANP-C

Peoria, Arizona, 85381, United States

Location

Agnes Oblas APRN

Phoenix, Arizona, 85044, United States

Location

Arcadia Well Woman

Scottsdale, Arizona, 85251, United States

Location

Patricia A Faust

Tempe, Arizona, 85283, United States

Location

Beth Andresen

Tucson, Arizona, 85704, United States

Location

Teresa Mote RNC NP

Tucson, Arizona, 85704, United States

Location

Brenda Hanson-Smith, RN, DNS, OGNP

El Dorado Hills, California, 95726, United States

Location

Lynda Reed

Ontario, California, 91762, United States

Location

Rose Mary Mosher

Rolling Hills Est., California, 90274, United States

Location

Evan Vapnek MD

San Diego, California, 92103, United States

Location

Marilyn Brooks

San Jacinto, California, 92583, United States

Location

Healthworks

San Luis Obispo, California, 93405, United States

Location

Maureen Allen

Northglenn, Colorado, 80234, United States

Location

Kristan Langdon, ANP-C

Parker, Colorado, 80134, United States

Location

Karen D. Adamson

Salida, Colorado, 81201, United States

Location

Merrilyn H. McNatt APRN

New London, Connecticut, 06320, United States

Location

Jean Ohliger APRN

South Windsor, Connecticut, 06074, United States

Location

Arlena Falcon

Blountstown, Florida, 32424, United States

Location

Carl Spirazza

Boynton Beach, Florida, 33472, United States

Location

Khadra Mohamoud Osman mD

Fort Lauderdale, Florida, 33316, United States

Location

Shelly E Kramer ARNP

Lake Worth, Florida, 33461, United States

Location

Ivonne M. Reynolds

Margate, Florida, 33316, United States

Location

Susan Chappuis, ARNP-C

Ormond Beach, Florida, 32174, United States

Location

Elizabeth Tsarnas

Stuart, Florida, 34994, United States

Location

Bayside Gynecology, P.A.

Venice, Florida, 34285, United States

Location

Jeffrey C Seiler, MD

West Palm Beach, Florida, 33407, United States

Location

Deborah Cothran WHNP-BC

Albany, Georgia, 31707, United States

Location

Elizabeth Killebrew MD

Fayetteville, Georgia, 30214, United States

Location

Michael D Benson

Deerfield, Illinois, 60015, United States

Location

Laurie Knoke

DeKalb, Illinois, 60115, United States

Location

Sherry Owen, APN

Gurnee, Illinois, 60031, United States

Location

Julie Snow

Park Ridge, Illinois, 60068, United States

Location

Kathryn A. Copeland

Carmel, Indiana, 46032, United States

Location

Matthew Sprunger MD

Fort Wayne, Indiana, 46825, United States

Location

Tamara Meisel ARNP

Lakin, Kansas, 67860, United States

Location

Richard F. Ford MD

Ashland, Kentucky, 41105, United States

Location

Women's Care Center

Lexington, Kentucky, 40503, United States

Location

Tammi K Herkey

Bossier City, Louisiana, 71111, United States

Location

Stefanie A Schultis

Covington, Louisiana, 70433, United States

Location

Steven Lenowitz, MD

Bel Air, Maryland, 21014, United States

Location

Kathryn Cervi

Columbia, Maryland, 21044, United States

Location

Elizabeth P Sipala

Galena, Maryland, 21635, United States

Location

Deborah A. Davis, MSN, CRNP

Prince Frederick, Maryland, 20678, United States

Location

Martha Klay

Great Barrington, Massachusetts, 01230, United States

Location

Pioneer Valley Urology

Springfield, Massachusetts, 01107, United States

Location

Margaret Duggan

Walpole, Massachusetts, 02081, United States

Location

Kathryn Koches

Dearborn, Michigan, 48124, United States

Location

Women's Health Care Specialists, PC

Paw Paw, Michigan, 49079, United States

Location

Isabel M Raposo

Riverview, Michigan, 48193, United States

Location

Laura Hintz

Saginaw, Michigan, 48638, United States

Location

Mickie G. Autry PhD, NP-C

Jackson, Mississippi, 39202, United States

Location

Kathleen M. Young RNC NP

Kalispell, Montana, 59901, United States

Location

Urogynecology Arts of New Jersey

East Brunswick, New Jersey, 08816, United States

Location

Lynda M. Adamson

Galloway, New Jersey, 08205, United States

Location

Women's Total Health

Hamburg, New Jersey, 07419, United States

Location

Cindy Nevara APN

Vineland, New Jersey, 08360, United States

Location

Jeanne Ann Dahl, RNC, WHNP

Albany, New York, 12205, United States

Location

Meredith Schledorn

Cortland, New York, 13045, United States

Location

Raj Mahajan MD

Oswego, New York, 13126, United States

Location

Diane Stonemetz

West Seneca, New York, 14224, United States

Location

Kathy Edwards

Minot, North Dakota, 58703, United States

Location

Columbus OB/Gyn Inc.

Columbus, Ohio, 43213, United States

Location

Holly Murphy

Columbus, Ohio, 43213, United States

Location

Susan Frost

Columbus, Ohio, 43222, United States

Location

Amy G Brenner M.D

Fairfield, Ohio, 45014, United States

Location

Elizabeth D. Allen CNP

Gallipolis, Ohio, 45631, United States

Location

William Shuler, MD

Tulsa, Oklahoma, 74133, United States

Location

Deborah Malone

Bend, Oregon, 97701, United States

Location

Anne Marie Moore, Womens Health Nurse Practitioner

Eugene, Oregon, 97401, United States

Location

Cathleen Ann Folk FNP

Portland, Oregon, 97219, United States

Location

Mary L Hagood, FNP-C

Roseburg, Oregon, 97470, United States

Location

Institute for Female Pelvic Medicine

Allentown, Pennsylvania, 18103, United States

Location

Paulette Schreiber, CRNP

Saint Mary's, Pennsylvania, 15857, United States

Location

Marie T Ziegler

West Chester, Pennsylvania, 19380, United States

Location

Nancy Newman RNC, WHNP

Lexington, South Carolina, 29072, United States

Location

Sharon Little

Collierville, Tennessee, 38017, United States

Location

Margaret A. Hull

Franklin, Tennessee, 37067, United States

Location

Urology Associates, P.C.

Nashville, Tennessee, 37209, United States

Location

John Pickel MD

Arlington, Texas, 76014, United States

Location

Christopher J. Jayne, MD, FACOG

Houston, Texas, 77030, United States

Location

Urology San Antonio

San Antonio, Texas, 78229, United States

Location

Marney Kidwell RNC

San Antonio, Texas, 78232, United States

Location

D. Crawford Allison MD

Waco, Texas, 76708, United States

Location

Laura C. Maw

Lehi, Utah, 84043, United States

Location

Betsy Browning

Bennington, Vermont, 05201, United States

Location

Anne L Stephens

Chesapeake, Virginia, 23320, United States

Location

Rand Gynecology, LLC

Chesapeake, Virginia, 23320, United States

Location

Julie Spencer

Lansdowne, Virginia, 20176, United States

Location

Patrice C Malena

Newport News, Virginia, 23602, United States

Location

Ocean Beach Women's Clinic

Ilwaco, Washington, 98624, United States

Location

Kimberly Scheer

Vashon, Washington, 98070, United States

Location

Primary Care, PLLC

Christiansted, VI, 00820, Virgin Islands

Location

MeSH Terms

Conditions

Urinary IncontinenceUrinary Incontinence, UrgeUrinary Incontinence, Stress

Condition Hierarchy (Ancestors)

Urination DisordersUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesLower Urinary Tract SymptomsUrological ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Julia Shaw, MD

    Director of Women's Health, Yale University

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
phase 4
Allocation
NA
Masking
NONE
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY

Study Record Dates

First Submitted

February 17, 2010

First Posted

February 23, 2010

Study Start

February 1, 2010

Primary Completion

June 1, 2011

Study Completion

June 1, 2011

Last Updated

July 14, 2011

Record last verified: 2011-07

Locations