Understanding Sleep in Hospitalized Older Patients

NCT01057823 | Completed

• 2 other identifiers: 16685B1K23AG033763-01
• Study Type: observational
• Target: 771
• Locations: 1 country
• Sites: 1

Brief Summary

The overall goal of this research is to elucidate how environmental, healthcare, and patient-level factors and patients' level of perceived control impact sleep duration and quality in hospitalized older patients and to assess whether better in-hospital sleep is associated with improved physical activity and health outcomes. We hypothesize that environment, healthcare disruptions and patient symptoms will be significantly associated with objective and subjective sleep duration and sleep quality in hospitalized older patients. We also hypothesize that a high level of perceived control will be associated with improved sleep duration and quality in hospitalized older patients. We further hypothesize that shorter sleep duration and quality in hospitalized older adults will be associated with adverse health outcomes, namely higher blood pressure and blood sugar.

Conditions

Sleep Deprivation; Sleep Fragmentation

Keywords

aged; sleep deprivation; actigraphy; ambulatory monitoring

Outcome Measures

Primary Outcomes (1)

• Sleep will be measured using subjective reports (Karolinska Sleep Diary on Daily Sleep Assessment).

  January 2010-January 2015

Secondary Outcomes (1)

• Sleep will also be measured objectively using actigraphy.

  January 2010-January 2015

Study Arms (1)

Inpatient Elders Age 50 and up

The study population is community-dwelling ambulatory patients age 50 or above hospitalized on the University of Chicago general medicine service. Exclusion criteria include: (1) transfer from the ICU or another hospital; (2) cognitively impaired; (3) not ambulatory; (4) residents of a nursing home or skilled nursing facility; (5) on bedrest; (6)documented sleep disorder in their medical history (i.e. obstructive sleep apnea, narcolepsy, etc).

Eligibility Criteria

• Age: 50 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Community-dwelling ambulatory patients age 50 or above hospitalized on the University of Chicago general medicine service.

You may qualify if:

• Age 50 or above
• Hospitalized on General Medicine service
• Ambulatory
• Community Dwelling
• MMSE \>17

You may not qualify if:

• transfer from the ICU or another hospital
• cognitively impaired
• not ambulatory
• residents of a nursing home or skilled nursing facility
• on bedrest
• documented sleep disorder in their medical history

Sponsors & Collaborators

• University of Chicago: lead
• National Institute on Aging (NIA): collaborator

Study Sites (1)

The University of Chicago Medical Center

Chicago, Illinois, 60637, United States

Location

Related Publications (4)

• Arora VM, Chang KL, Fazal AZ, Staisiunas PG, Meltzer DO, Zee PC, Knutson KL, Van Cauter E. Objective sleep duration and quality in hospitalized older adults: associations with blood pressure and mood. J Am Geriatr Soc. 2011 Nov;59(11):2185-6. doi: 10.1111/j.1532-5415.2011.03644.x. No abstract available.

  PMID: 22098044 RESULT

• Yoder JC, Staisiunas PG, Meltzer DO, Knutson KL, Arora VM. Noise and sleep among adult medical inpatients: far from a quiet night. Arch Intern Med. 2012 Jan 9;172(1):68-70. doi: 10.1001/archinternmed.2011.603. No abstract available.

  PMID: 22232151 RESULT

• Adachi M, Staisiunas PG, Knutson KL, Beveridge C, Meltzer DO, Arora VM. Perceived control and sleep in hospitalized older adults: a sound hypothesis? J Hosp Med. 2013 Apr;8(4):184-90. doi: 10.1002/jhm.2027. Epub 2013 Mar 18.

  PMID: 23504939 RESULT

• DePietro RH, Knutson KL, Spampinato L, Anderson SL, Meltzer DO, Van Cauter E, Arora VM. Association Between Inpatient Sleep Loss and Hyperglycemia of Hospitalization. Diabetes Care. 2017 Feb;40(2):188-193. doi: 10.2337/dc16-1683. Epub 2016 Nov 30.

  PMID: 27903614 DERIVED

MeSH Terms

Conditions

Sleep Deprivation

Condition Hierarchy (Ancestors)

Dyssomnias; Sleep Wake Disorders; Nervous System Diseases; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Mental Disorders

Study Officials

• Vineet M Arora, MD, MA

  University of Chicago

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 26, 2010
• First Posted: January 27, 2010
• Study Start: January 1, 2010
• Primary Completion: July 19, 2019
• Study Completion: July 19, 2020
• Last Updated: May 17, 2021

Record last verified: 2021-05

Locations

US (1)