NCT00272233

Completed

Effects of Sleep Loss on Endothelial Function and Cytokine L...

Yale University Source

Other study identifiers

Sponsor study identifier

HIC26414

Secondary identifiers

NIH NHLBI K24 04024

Study Type

observational

Reported enrollment (type unavailable)

22

Locations

1 country

Sites

1

Timeline

Study Start

December 2004

Date type not reported

This date has not been verified as actual or estimated.

Primary Completion

Not reported

Date not reported

Study Completion

June 2005

Date type not reported

This date has not been verified as actual or estimated.

Brief Summary

Work requirements for medical trainees result in substantial sleep loss. Sleep loss has been associated with increased levels of certain inflammatory hormones that could have negative impact on blood vessel function. The purpose of this study is to determine the effects of sleep loss on blood hormone levels and blood vessel function in medical trainees.

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: completed
Reported enrollment (type unavailable): 22 participants
Study completion date: June 2005
Date type not reported
This date has not been verified as actual or estimated.
Listed locations: 1 countries · 1 sites

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

Study Start
December 2004
Date type not reported
This date has not been verified as actual or estimated.
Study Completion
June 2005
Date type not reported
This date has not been verified as actual or estimated.
First Submitted
January 3, 2006
Actual (reported)
First Posted
January 4, 2006
Actual (reported)

Last Updated: March 20, 2007
Status Verified: January 2006
Last Update Submitted: March 19, 2007

Conditions

Sleep Deprivation

Keywords

Inflammation Mediators [D23.469]Cardiovascular Physiologic Phenomena [G09.330.553]

Eligibility Criteria

Age18 Years - 40 Years

Sexall

Healthy VolunteersYes

Age GroupsAdult (18-64)

You may qualify if:

Medical resident in MICU rotation
Non-smoker
Body mass index \<28 kg/m2

You may not qualify if:

Systolic blood pressure \>140 mmHg; Diastolic blood pressure \>90 mmHg

Sponsors & Collaborators

National Heart, Lung, and Blood Institute (NHLBI)
NIHcollaborator
Yale University
Otherlead
National Center for Research Resources (NCRR)

Study Sites (1)

Yale University School of Medicine

New Haven, Connecticut, 06510, United States

MeSH Terms

Conditions

Sleep Deprivation

Condition Hierarchy (Ancestors)

DyssomniasSleep Wake DisordersNervous System DiseasesNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsMental Disorders

Study Officials

Stuart D Katz, MD
Yale University
PRINCIPAL INVESTIGATOR

Study Design

Study Type: observational
Observational Model: DEFINED POPULATION
Time Perspective: PROSPECTIVE
Sponsor Type: OTHER

Study Record Dates

First Submitted

January 3, 2006

First Posted

January 4, 2006

Study Start

December 2004

Date type not reported

This date has not been verified as actual or estimated.

Study Completion

June 2005

Date type not reported

NCT05381532

Menstrual-phase-dependent Differences in Response to Sleep Loss

Not ApplicableCompleted

NCT00669513

Cardiovascular Effects of Partial Sleep Deprivation

Phase 3Completed

NCT04535219

Effect of Total Sleep Deprivation on Vascular Function

Not ApplicableCompleted

NCT01334788

Sleep Deprivation and Energy Balance

Not ApplicableCompleted

NCT00228215

Tips for Infant and Parent Sleep (TIPS)

Not ApplicableCompleted

NCT06636318

Immune Status After Being on Call for 24 Hrs

Recruiting

Known history of diabetes mellitus, hypertension, hyperlipidemia

Known history of acute or chronic inflammatory or infectious disease

Known history of sleep disturbance unrelated to work

Pregnancy

Contact the study team to confirm eligibility.

NIHcollaborator

This date has not been verified as actual or estimated.

Last Updated

March 20, 2007

Record last verified: 2006-01

Source record

Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.

Source: ClinicalTrials.gov.

JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.

Registry identifier: NCT00272233
Data provider: ClinicalTrials.gov
Source updated: 2007-03-20
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:38:55 UTC

Locations

US(1)

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Study Completion

First Submitted

First Posted

Conditions

Keywords

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Study Design

Study Record Dates

Source record

Locations