NCT00956774

Brief Summary

The aim of this study is to compare the three commonly used hysterosalpingography (HSG) injection devices on the basis of patient pain perception, total fluoroscopic and procedural time, and side effects in a prospective, randomized study. An important and novel secondary outcome is the comparison of the quality of images obtained with these three devices. The investigators hypothesize that the balloon catheter and cervical vacuum cup will be less painful than the acorn tipped cannula and that there will be no difference in image quality between the three groups.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
114

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Feb 2009

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2009

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

August 10, 2009

Completed
1 day until next milestone

First Posted

Study publicly available on registry

August 11, 2009

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2010

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2010

Completed
Last Updated

April 25, 2022

Status Verified

February 1, 2013

Enrollment Period

1 year

First QC Date

August 10, 2009

Last Update Submit

April 19, 2022

Conditions

Keywords

HSGCannulaHSG procedureinfertility evaluation

Outcome Measures

Primary Outcomes (1)

  • pain scores

    15 minutes

Secondary Outcomes (4)

  • the total duration of the procedure

    15 minutes

  • direct fluoroscopic time

    15 minutes

  • rates of vasovagal reaction

    15 minutes

  • diagnostic quality of images obtained

    1 month

Study Arms (3)

Balloon Catheter

ACTIVE COMPARATOR
Procedure: HSG with balloon catheter

Cervical Vacuum Cup

ACTIVE COMPARATOR
Procedure: HSG with cervical vacuum cup

acorn-tipped cannula

ACTIVE COMPARATOR
Procedure: HSG with acorn-tipped cannula

Interventions

Use of acorn-tipped cannula for HSG to evaluate tubal patency

acorn-tipped cannula

cup placed over cervix to create vacuum pressure.

Cervical Vacuum Cup

balloon inserted via catheter into cervic for dilation.

Balloon Catheter

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Women undergoing HSG at an academic medical center

You may not qualify if:

  • Contrast media allergy
  • Prior LEEP (Loop Electrosurgical Excision Procedure) or other cervical procedure
  • Contraindication to NSAID use
  • Known active pelvic infection
  • Active vaginal bleeding

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Carolinas Medical Center

Charlotte, North Carolina, 28203, United States

Location

MeSH Terms

Conditions

Infertility

Condition Hierarchy (Ancestors)

Genital DiseasesUrogenital Diseases

Study Officials

  • Sara Lane, MD

    Carolinas Medical Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
DIAGNOSTIC
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 10, 2009

First Posted

August 11, 2009

Study Start

February 1, 2009

Primary Completion

February 1, 2010

Study Completion

February 1, 2010

Last Updated

April 25, 2022

Record last verified: 2013-02

Locations