Study Stopped
investigator changed location, requires new training effort
In Vitro Maturation With in Vitro Fertilization (IVF) Compared to Mild in Vitro Fertilization
IVM vs IVF
Clinical Research Study on in Vitro Maturation With IVF Compared to Mild Stimulation IVF
1 other identifier
interventional
1,440
1 country
2
Brief Summary
Methods of infertility treatment may involve in vitro fertilization or IVF. Though effective, IVF is complex and expensive. Methods using no gonadotropin hormone stimulation of the ovaries are being compared to mild stimulation doses. The goal of the research is to determine which of these if more suitable as a low cost approach for varying individual patients.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Mar 2009
Longer than P75 for not_applicable
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 1, 2009
CompletedFirst Submitted
Initial submission to the registry
March 23, 2009
CompletedFirst Posted
Study publicly available on registry
March 24, 2009
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2011
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2012
CompletedAugust 11, 2010
March 1, 2009
2.8 years
March 23, 2009
August 10, 2010
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Cost effectiveness
two years
Secondary Outcomes (1)
Ongoing pregnancy rates per cycle
3 months
Study Arms (2)
IVM
EXPERIMENTALEarly egg retrieval, in vitro maturation, then IVF
Mild IVF
ACTIVE COMPARATORMild gonadotropin and conventional IVF
Interventions
No gonadotropin, eggs harvested early
Gonadotropin followed by conventional IVF
Eligibility Criteria
You may qualify if:
- Under age 42 female, normal uterine cavity, BMI 18-34kg/m2,
You may not qualify if:
- Donor eggs, donor sperm, myoma over 5 cm
- Current hydrosalpinx, abnormal uterine cavity.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (2)
Batzofin Fertilty Services
New York, New York, 10016, United States
BFS
New York, New York, United States
Related Publications (2)
Son WY, Chung JT, Herrero B, Dean N, Demirtas E, Holzer H, Elizur S, Chian RC, Tan SL. Selection of the optimal day for oocyte retrieval based on the diameter of the dominant follicle in hCG-primed in vitro maturation cycles. Hum Reprod. 2008 Dec;23(12):2680-5. doi: 10.1093/humrep/den332. Epub 2008 Sep 4.
PMID: 18775885BACKGROUNDSon WY, Chung JT, Demirtas E, Holzer H, Sylvestre C, Buckett W, Chian RC, Tan SL. Comparison of in-vitro maturation cycles with and without in-vivo matured oocytes retrieved. Reprod Biomed Online. 2008 Jul;17(1):59-67. doi: 10.1016/s1472-6483(10)60294-5.
PMID: 18616892BACKGROUND
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Joe B Massey, MD
Batzofin Fertility Services
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- HEALTH SERVICES RESEARCH
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
March 23, 2009
First Posted
March 24, 2009
Study Start
March 1, 2009
Primary Completion
December 1, 2011
Study Completion
June 1, 2012
Last Updated
August 11, 2010
Record last verified: 2009-03