NCT00951249

Brief Summary

It has been estimated that black men who have sex with men (MSM) account for one quarter of all new HIV infections in the US annually, yet little prevention work has been directed towards this population. The purpose of this study is to research and potentially design a new and better way to try and slow the spread of HIV among black MSM.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,553

participants targeted

Target at P75+ for not_applicable hiv-infections

Timeline
Completed

Started Jul 2009

Geographic Reach
1 country

8 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2009

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

July 31, 2009

Completed
4 days until next milestone

First Posted

Study publicly available on registry

August 4, 2009

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2011

Completed
Last Updated

August 26, 2022

Status Verified

August 1, 2022

Enrollment Period

2.4 years

First QC Date

July 31, 2009

Last Update Submit

August 25, 2022

Conditions

Keywords

MSMHIV infectionsHIV Seronegativity

Outcome Measures

Primary Outcomes (8)

  • Number of participants enrolled at each city

    At 52 Weeks

  • Proportion of participants who agree to HIV testing

    Throughout study

  • Proportion of participants who agree to STI testing

    Throughout study

  • Proportion of participants who use PHN

    Throughout study

  • Proportion of participants who are newly diagnosed with HIV at enrollment

    At Study Entry

  • Increase in condom use

    Study Entry to Week 52

  • Decrease in viral load among HIV-infected participants who initiate HAART during their study participation

    At Week 52

  • Decrease in STI

    At Study Entry to Week 52

Secondary Outcomes (11)

  • Number of participants with recent HIV infection

    At Study Entry

  • Number of participants with acute HIV infection

    At Week 52

  • Number of seroconversions during follow-up among those who are HIV-uninfected

    At Follow-up

  • Number of sex partners

    At Study Entry, and Weeks 26 and 52

  • Number of sero-discordant or sero-unknown partners

    At Study Entry, and Weeks 26 and 52

  • +6 more secondary outcomes

Study Arms (1)

A

EXPERIMENTAL

HIV-infected and uninfected black MSM

Behavioral: Referral of PartnersBehavioral: Screening for STIs and counselingBehavioral: Peer health care system navigatorsBehavioral: Enhanced counseling

Interventions

Referral of up to five sexual partners by index participants for enrollment into the study

A

Identification of STIs and treatment or referral for treatment, if applicable

A

HIV/STI treatment and other medical and social services

A

Counseling and referral for care offered to participants for issues such as substance use and mental health

A

Eligibility Criteria

Age18 Years+
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Willing and able to provide informed consent
  • Black, African American, Caribbean Black, or multiethnic Black
  • At least one instance of unprotected anal intercourse (UAI) with a man in the past six months
  • Residing in the metropolitan area and do not plan to move away during the time of study participation

You may not qualify if:

  • Co-enrollment in any other HIV interventional research study or have been enrolled in an HIV vaccine trial in which they were either in the active arm or do not know the arm in which they were enrolled.
  • Would be enrolled as a community-recruited participant in a category that has already reached its enrollment cap
  • Any medical, psychiatric, or social condition, or occupational or other responsibility that, in the judgment of the investigator, would make participation in the study unsafe, complicate interpretation of study outcome data, or otherwise interfere with achieving the study objectives

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (8)

UCLA Vine Street CRS

Los Angeles, California, 90038, United States

Location

San Francisco Vaccine and Prevention CRS

San Francisco, California, 94102, United States

Location

George Washington University

Washington D.C., District of Columbia, 20037, United States

Location

The Ponce de Leon Ctr. CRS

Atlanta, Georgia, 30308, United States

Location

Hope Clinic of the Emory Vaccine Center CRS

Decatur, Georgia, 30030, United States

Location

The Fenway Institute

Boston, Massachusetts, 02115, United States

Location

NY Blood Ctr./Union Square CRS

New York, New York, 10003, United States

Location

Harlem Hospital Center/Columbia University CRS

New York, New York, 10032, United States

Location

Related Publications (2)

  • Bissessor M, Fairley CK, De Guingand D, Bradshaw CS, Chen MY. Delay in the diagnosis of early syphilis among men who have sex with men: need for greater community and health provider education. Int J STD AIDS. 2009 Jan;20(1):52-3. doi: 10.1258/ijsa.2008.008254.

    PMID: 19103894BACKGROUND
  • Rowniak S. Safe sex fatigue, treatment optimism, and serosorting: new challenges to HIV prevention among men who have sex with men. J Assoc Nurses AIDS Care. 2009 Jan-Feb;20(1):31-8. doi: 10.1016/j.jana.2008.09.006.

    PMID: 19118769BACKGROUND

MeSH Terms

Conditions

HIV Infections

Interventions

Mass ScreeningCounseling

Condition Hierarchy (Ancestors)

Blood-Borne InfectionsCommunicable DiseasesInfectionsSexually Transmitted Diseases, ViralSexually Transmitted DiseasesLentivirus InfectionsRetroviridae InfectionsRNA Virus InfectionsVirus DiseasesGenital DiseasesUrogenital DiseasesImmunologic Deficiency SyndromesImmune System Diseases

Intervention Hierarchy (Ancestors)

Diagnostic Techniques and ProceduresDiagnosisHealth SurveysSurveys and QuestionnairesData CollectionEpidemiologic MethodsInvestigative TechniquesDiagnostic ServicesPreventive Health ServicesHealth ServicesHealth Care Facilities Workforce and ServicesHealth Care Evaluation MechanismsQuality of Health CareHealth Care Quality, Access, and EvaluationPublic HealthEnvironment and Public HealthPublic Health PracticeMental Health ServicesBehavioral Disciplines and ActivitiesCommunity Health Services

Study Officials

  • Beryl Koblin, PhD

    New York Blood Center

    STUDY CHAIR
  • Kenneth Mayer, MD

    Fenway Community Health Center

    STUDY CHAIR
  • Darrell P. Wheeler, PhD, MPH, ACSW

    School of Social Work, Hunter College

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
SINGLE GROUP
Sponsor Type
NETWORK
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 31, 2009

First Posted

August 4, 2009

Study Start

July 1, 2009

Primary Completion

December 1, 2011

Study Completion

December 1, 2011

Last Updated

August 26, 2022

Record last verified: 2022-08

Locations