Key Highlights

Risk & Performance

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 45/100

Failure Rate

10.1%

349 terminated/withdrawn out of 3442 trials

Success Rate

88.3%

+1.8% vs industry average

Late-Stage Pipeline

11%

370 trials in Phase 3/4

Results Transparency

34%

883 of 2625 completed trials have results

Key Signals

261 recruiting883 with results234 terminated115 withdrawn

Enrollment Performance

Analytics

Phase 1

1149(43.3%)

Phase 2

686(25.9%)

N/A

417(15.7%)

Phase 3

211(8.0%)

Phase 4

159(6.0%)

Early Phase 1

29(1.1%)

2651Total

Phase 1(1149)

Phase 2(686)

N/A(417)

Phase 3(211)

+2 more

Activity Timeline

Global Presence

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Clinical Trials (3442)

Showing 20 of 3442 trials

NCT07215871Phase 1Enrolling By Invitation

Rechallenge With a Low Pathogenicity Avian H10N7 Influenza Virus in Healthy Human Volunteers Previously Challenged With H10N7 Influenza

Role: lead

NCT05652478Phase 2Recruiting

Early Metabolic Effects of Antiretroviral Drugs in Healthy volUnteers: a Phase 2 Randomized Study

Role: lead

NCT04097561Phase 1Recruiting

Safety of Belimumab in People With Idiopathic CD4 Lymphopenia and Autoantibodies (Phoebe)

Role: lead

NCT07262983Phase 1Recruiting

Evaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or Atopic Dermatitis

Role: lead

NCT06607003Phase 1Recruiting

Induced Blood-Stage Malaria in Healthy Malaria-Naive Adults to Assess the Safety and Infectivity of Plasmodium Vivax Challenge Agent and Evaluate Transmission in Mosquito Feeding Assays

Role: lead

NCT05285891Phase 4Recruiting

Ocrelizumab Discontinuation in Relapsing Multiple Sclerosis

Role: lead

NCT07027826Not ApplicableRecruiting

The Esophageal String Test as a Diagnostic Screening Tool for Eosinophilic Esophagitis Among Africans With Dysphagia in Mali and the United States

Role: lead

NCT07271381Not ApplicableRecruiting

THREAT: Testing Harms Related to Exposure to Allergenic and Epithelial Toxins

Role: lead

NCT06730126Phase 2Recruiting

Study of the ITK Inhibitor Soquelitinib to Reduce Lymphoproliferation and Improve Cytopenias in Autoimmune Lymphoproliferative Syndrome (ALPS)-FAS Patients

Role: lead

NCT06479837Recruiting

Modeling Host-Pathogen Interaction Using Lymphoid Organoids

Role: lead

NCT06546423Phase 1Completed

Study of the Infectivity, Safety and Immunogenicity of Two Recombinant, Live-Attenuated, B/HPIV3 Vectored Vaccines Expressing the Fusion Glycoprotein of HMPV Delivered by Nasal Spray to HPIV3-Seropositive Children 24 to <60 Months of Age

Role: lead

NCT03895645Enrolling By Invitation

Connors Protocol for the Management and Use of Stored Human Specimens (Stored Human Specimens)

Role: lead

NCT07416201Recruiting

Natural History of Dysregulation and Aging of the Immune System in People With Trisomy 21 With and Without Thymectomy

Role: lead

NCT05652504Phase 1Suspended

Safety Evaluation of PfSPZ Vaccine in Pregnant Women in Mali (MalVIP1)

Role: lead

NCT05512949Phase 2Completed

Trial to Evaluate the Immunogenicity of Dose Reduction Strategies of the MVA-BN Monkeypox Vaccine