Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 45/100

Failure Rate

10.1%

351 terminated/withdrawn out of 3473 trials

Success Rate

88.3%

+1.8% vs industry average

Late-Stage Pipeline

11%

373 trials in Phase 3/4

Results Transparency

34%

915 of 2656 completed trials have results

Key Signals

261 recruiting915 with results236 terminated115 withdrawn

Enrollment Performance

Analytics

Phase 1
1163(43.4%)
Phase 2
690(25.8%)
N/A
423(15.8%)
Phase 3
212(7.9%)
Phase 4
161(6.0%)
Early Phase 1
29(1.1%)
2678Total
Phase 1(1163)
Phase 2(690)
N/A(423)
Phase 3(212)
+2 more

Activity Timeline

Global Presence

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Clinical Trials (3473)

Showing 20 of 3473 trials
NCT05652504Phase 1Suspended

Safety Evaluation of PfSPZ Vaccine in Pregnant Women in Mali (MalVIP1)

Role: lead

NCT06214910Not ApplicableCompleted

ThiPhiSA: New Pathways to Prevention From Community TB Screening in South Africa

Role: collaborator

NCT07683104Recruiting

Natural History of Trisomy 8-Associated Autoinflammatory Disease (TRIAD) and Related Disorders

Role: lead

NCT00246857Recruiting

Screening Protocol for Genetic Diseases of Lymphocyte Homeostasis and Programmed Cell Death

Role: lead

NCT07215858Phase 2Recruiting

BPL-1357 Against H1N1 Influenza Virus Challenge

Role: lead

NCT00719719Completed

Cause of Unexplained Anaphylaxis

Role: lead

NCT03092505Completed

Herpesviruses Reactivation In Hiv-Infected Women Initiating ART (HERA)

Role: lead

NCT00029445Recruiting

Leukapheresis to Obtain Plasma or Lymphocytes for Studies of HIV-infected Patients, Including Long-term Non-progressors

Role: lead

NCT06325709Phase 1Recruiting

Base Editing for Mutation Repair in Hematopoietic Stem & Progenitor Cells for X-Linked Chronic Granulomatous Disease

Role: lead

NCT05580458Phase 1Recruiting

Safety and Immunogenicity of Recombinant Varicella Zoster Virus Vaccine in People With HIV Who Have a CD4 Count Less Than 300 or Greater Than or Equal to 300 and a Healthy Control Population

Role: lead

NCT07706686Phase 1Recruiting

Phase 1 Challenge Study Using rDEN2delta30-7169 to Evaluate Host-Pathogen Interactions in Primary, Homotypic, and Heterotypic Dengue Virus Infection

Role: lead

NCT07027826Not ApplicableRecruiting

The Esophageal String Test as a Diagnostic Screening Tool for Eosinophilic Esophagitis Among Africans With Dysphagia in Mali and the United States

Role: lead

NCT06479837Recruiting

Modeling Host-Pathogen Interaction Using Lymphoid Organoids

Role: lead

NCT06607003Phase 1Recruiting

Induced Blood-Stage Malaria in Healthy Malaria-Naive Adults to Assess the Safety and Infectivity of Plasmodium Vivax Challenge Agent and Evaluate Transmission in Mosquito Feeding Assays

Role: lead

NCT04034264Recruiting

Febrile Disease Landscape in Cambodia Via Metagenomic Pathogen Sequencing

Role: lead

NCT04794829Completed

Natural History of Systemic and Nasal Mucosal Immunity to Influenza and SARS-CoV-2 in Adults After Vaccination

Role: lead

NCT07737275Not ApplicableNot Yet Recruiting

Screening With Portable X-rays for Rapid Recognition of TB

Role: collaborator

NCT05078905Active Not Recruiting

Vaccine Responses to SARS-CoV-2 and Other Emerging Infectious Diseases

Role: lead

NCT05656378Recruiting

A Repository to Study Host-Microbiome Interactions in Health and Disease

Role: lead

NCT07262983Phase 1Recruiting

Evaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or Atopic Dermatitis

Role: lead