Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 45/100

Failure Rate

10.1%

351 terminated/withdrawn out of 3459 trials

Success Rate

88.3%

+1.8% vs industry average

Late-Stage Pipeline

11%

371 trials in Phase 3/4

Results Transparency

34%

897 of 2644 completed trials have results

Key Signals

264 recruiting897 with results236 terminated115 withdrawn

Enrollment Performance

Analytics

Phase 1
1156(43.4%)
Phase 2
689(25.9%)
N/A
420(15.8%)
Phase 3
211(7.9%)
Phase 4
160(6.0%)
Early Phase 1
29(1.1%)
2665Total
Phase 1(1156)
Phase 2(689)
N/A(420)
Phase 3(211)
+2 more

Activity Timeline

Global Presence

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Clinical Trials (3459)

Showing 20 of 3459 trials
NCT03394053Recruiting

The Mechanistic Biology of Primary Immunodeficiency Disorders

Role: lead

NCT03895645Enrolling By Invitation

Connors Protocol for the Management and Use of Stored Human Specimens (Stored Human Specimens)

Role: lead

NCT07019883Phase 1Completed

A Study to Evaluate the Safety and Immunogenicity of Two Doses of a Novel H5 Central Antigen mRNA-LNP in Healthy Adults

Role: lead

NCT06709521Phase 4Recruiting

Optimization of Beta-lactam Dosing in Critically Ill Patients With Cystatin C (OPTIMIZE-GNI)

Role: lead

NCT04350138Phase 2Active Not Recruiting

Safety and Efficacy Study of Meningococcal Group B Vaccine rMenB+OMV NZ (Bexsero) to Prevent Gonococcal Infection

Role: lead

NCT02015013Phase 2Recruiting

Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models

Role: lead

NCT07271381Not ApplicableRecruiting

THREAT: Testing Harms Related to Exposure to Allergenic and Epithelial Toxins

Role: lead

NCT06479837Recruiting

Modeling Host-Pathogen Interaction Using Lymphoid Organoids

Role: lead

NCT06745921Phase 1Active Not Recruiting

Safety and Immunogenicity of an Inactivated West Nile Virus Vaccine in Healthy Adults

Role: lead

NCT05652478Phase 2Recruiting

Early Metabolic Effects of Antiretroviral Drugs in Healthy volUnteers: a Phase 2 Randomized Study

Role: lead

NCT04926922Completed

PREVAIL VIIIa: Evaluation of Latent Tuberculosis Infection Screening Methods in People Living With Retroviral Infection in Liberia

Role: lead

NCT07416201Recruiting

Natural History of Dysregulation and Aging of the Immune System in People With Trisomy 21 With and Without Thymectomy

Role: lead

NCT07644195Phase 1Not Yet Recruiting

Study to Evaluate Safety and Activity of Inhaled TRL1068 in Healthy Volunteers

Role: collaborator

NCT02116764Completed

Analysis of Patients Treated for Chronic Granulomatous Disease Since January 1, 1995

Role: lead

NCT05929911Not ApplicableRecruiting

Open Trial of Trauma-focused Psychodynamic Psychotherapy for People Living With HIV and PTSD

Role: collaborator

NCT06739915Not ApplicableCompleted

Targeted Universal TB Testing With Simultaneous TPT Prescribing Among People Living With HIV in South Africa

Role: collaborator

NCT07536308Phase 1Recruiting

A Safety and Immunogenicity Trial of OCU500, ChAd36 Vector Encoding SARS-CoV-2 Spike Vaccine Via Intranasal and Inhalational Routes in Previously Vaccinated Adults

Role: lead

NCT00339287Recruiting

Molecular Basis of Human Phagocyte Interactions With Bacterial Pathogens

Role: lead

NCT06735209Phase 1Active Not Recruiting

First-in-Human PfSPZ-LARC2 Vaccination/CHMI

Role: lead

NCT07262983Phase 1Recruiting

Evaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or Atopic Dermatitis

Role: lead