NCT00653991

Brief Summary

This study will evaluate the effectiveness of an interactive virtual environment computer game in reducing risky sexual behaviors among men who have sex with men.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2,020

participants targeted

Target at P75+ for not_applicable hiv-infections

Timeline
Completed

Started Jun 2011

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 3, 2008

Completed
4 days until next milestone

First Posted

Study publicly available on registry

April 7, 2008

Completed
3.2 years until next milestone

Study Start

First participant enrolled

June 1, 2011

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2012

Completed
7 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2013

Completed
6.2 years until next milestone

Results Posted

Study results publicly available

July 16, 2019

Completed
Last Updated

July 16, 2019

Status Verified

June 1, 2019

Enrollment Period

1.3 years

First QC Date

April 3, 2008

Results QC Date

August 5, 2015

Last Update Submit

June 23, 2019

Conditions

Keywords

HIV/AIDS PreventionMen Who Have Sex With Men (MSM)Risky Sexual BehaviorSocially Optimized Learning in a Virtual Environment (SOLVE)HIV Seronegativity

Outcome Measures

Primary Outcomes (2)

  • Residualized Change in Counts of Unprotected Anal Intercourse at 3 Months

    Counts of unprotected anal intercourse (one each for insertive and receptive; UAI) in the past 3 months with a non-primary partner were reported by participants at baseline, and 3 month follow-up. Reports of insertive and receptive anal intercourse per time period were summed. Change in unprotected anal intercourse was calculated at 3 months using residualized change scores (regressing 3-month reported UAI (Y) on baseline UAI. Negative numbers reflect a reduction in UAI over time). Although raw counts of UAI are heavily tailed, residualized change scores yield a normal distribution.

    Measured at baseline and 3 month follow-up

  • Residualized Change in Counts of Unprotected Anal Intercourse at 6 Months

    Counts of unprotected anal intercourse (one each for insertive and receptive) in the past 3 months with a non-primary partner were reported by participants at baseline, and 6 month follow-up. Reports of insertive and receptive anal intercourse per time period were summed. Change in unprotected anal intercourse from baseline, was calculated at 6 months using residualized change scores (regressing 6-month reported UAI (Y) on baseline UAI. Negative numbers reflect a reduction in UAI over time). Raw counts of UAI are heavily tailed, but residualized change scores are normally distributed.

    Measured at baseline and 6 month follow-up

Secondary Outcomes (1)

  • Shame Residualized Change

    Measured at baseline and Immediate post

Study Arms (2)

SOLVE-IT

EXPERIMENTAL

Participants will receive the intervention SOLVE-IT. The SOLVE-IT intervention is a videogame designed to optimize self-regulation, reduce shame, and reduce risky choices for young men who have sex with men (YMSM).

Behavioral: SOLVE-IT

Waitlist Control

ACTIVE COMPARATOR

Participants will receive the intervention, SOLVE-IT, a video game designed to optimize self-regulation reduce shame, and reduce risky sexual choices for YMSM, after a 6-month waitlist period.

Behavioral: SOLVE-IT

Interventions

SOLVE-ITBEHAVIORAL

SOLVE-IT, a video game using computer-generated virtual agents, is the next generation of interactive media aimed at reducing risky sex among young MSM. Participants will interact in a virtual environment that focuses upon HIV prevention in a dating context.

Also known as: Socially Optimized Learning in Virtual Environments
SOLVE-ITWaitlist Control

Eligibility Criteria

Age18 Years - 24 Years
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Self-identifies as Latino, black, or Caucasian
  • Men who have sex with men
  • Not HIV infected
  • Engaged in unprotected anal sex at least twice in the 90 days before study entry with a nonprimary male partner
  • Has broadband access during course of study
  • Lives in United States
  • Biological male

You may not qualify if:

  • History of nonprescription drug injection use
  • Has participated in SOLVE-IT at any phase

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Southern California (University Village)

Los Angeles, California, 90007, United States

Location

Related Publications (1)

  • Read SJ, Miller, LC, Appleby PR, Nwosu ME, Reynaldo S, Lauren A, Putcha A. Socially optimized learning in a virtual environment: Reducing risky sexual behavior among men who have sex with men. Human Communication Research 32(1):1-34, 2006.

    BACKGROUND

MeSH Terms

Conditions

HIV InfectionsHomosexuality

Condition Hierarchy (Ancestors)

Blood-Borne InfectionsCommunicable DiseasesInfectionsSexually Transmitted Diseases, ViralSexually Transmitted DiseasesLentivirus InfectionsRetroviridae InfectionsRNA Virus InfectionsVirus DiseasesGenital DiseasesUrogenital DiseasesImmunologic Deficiency SyndromesImmune System DiseasesSexualitySexual BehaviorBehavior

Results Point of Contact

Title
Professor Lynn Carol Miller
Organization
Annenberg School for Communication and Journalism, University of Southern California

Study Officials

  • Lynn C. Miller, PhD

    University of Southern California

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Study Principal Investigator

Study Record Dates

First Submitted

April 3, 2008

First Posted

April 7, 2008

Study Start

June 1, 2011

Primary Completion

October 1, 2012

Study Completion

May 1, 2013

Last Updated

July 16, 2019

Results First Posted

July 16, 2019

Record last verified: 2019-06

Locations