NCT00948129

Brief Summary

This trial studies how well a mobile smoking cessation intervention works in enhancing cancer outreach in low-income adult smokers. Mobile smoking cessation intervention may help smokers quit or cut back on smoking, and help increase the range of cancer prevention services provided to low-income adult smokers.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
626

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Aug 2009

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 14, 2009

Completed
15 days until next milestone

First Posted

Study publicly available on registry

July 29, 2009

Completed
12 days until next milestone

Study Start

First participant enrolled

August 10, 2009

Completed
11.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 10, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 10, 2021

Completed
Last Updated

January 20, 2023

Status Verified

January 1, 2023

Enrollment Period

11.5 years

First QC Date

July 14, 2009

Last Update Submit

January 18, 2023

Conditions

Outcome Measures

Primary Outcomes (2)

  • Smoking abstinence rate

    The primary method of analysis will be mixed-model logistic regression.

    At 12 months

  • Cost-effectiveness

    Will perform an incremental cost-effectiveness analysis by comparing the expected economic costs and clinical benefits of the three strategies. Will create a decision-analytic model using TreeAge Pro 2007 software to conduct the incremental cost-effectiveness analysis.

    At 12 months

Secondary Outcomes (1)

  • Salivary cotinine levels

    At 12 months

Study Arms (3)

Group I (standard care)

ACTIVE COMPARATOR

Participants undergo standard of care smoking cessation intervention consisting of brief advice to quit smoking, NRT, and self-help written materials.

Other: Laboratory Biomarker AnalysisBehavioral: Smoking Cessation Intervention

Group II (enhanced care)

EXPERIMENTAL

Participants undergo standard of care smoking cessation intervention as in Group I and attend a health feedback counseling session at baseline. Participants also receive access to a smoking cessation hotline telephone number and supportive text messages daily for 12 weeks.

Other: Laboratory Biomarker AnalysisBehavioral: Smoking Cessation InterventionOther: Tobacco Cessation Counseling

Group III (intensive care)

EXPERIMENTAL

Participants undergo standard of care smoking cessation intervention as in Group I and attend a health feedback counseling session at baseline. Participants also receive access to a smoking cessation hotline telephone number, supportive text messages daily for 12 weeks, and a smoking cessation telephone call over 15 minutes weekly for 12 weeks.

Other: Laboratory Biomarker AnalysisBehavioral: Smoking Cessation InterventionBehavioral: Telephone-Based InterventionOther: Tobacco Cessation Counseling

Interventions

Correlative studies

Group I (standard care)Group II (enhanced care)Group III (intensive care)

Undergo standard of care smoking cessation intervention

Also known as: Smoking and Tobacco Use Cessation Interventions
Group I (standard care)Group II (enhanced care)Group III (intensive care)

Undergo telephone based smoking cessation intervention

Group III (intensive care)

Undergo smoking cessation counseling

Group II (enhanced care)Group III (intensive care)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Smoked at least 100 cigarettes in lifetime
  • English or Spanish speaking
  • Currently smoking at least 5 cigarettes a day, on average
  • Willing to set a quit smoking date within a week of the enrollment

You may not qualify if:

  • Positive history of a medical condition that precludes use of the nicotine patch
  • Current use of nicotine replacement therapy (NRT)
  • Current use of other smoking cessation medications (e.g., Chantix or Zyban)
  • Pregnant or nursing
  • Enrolled in another smoking cessation study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

M D Anderson Cancer Center

Houston, Texas, 77030, United States

Location

Related Publications (3)

  • Vidrine DJ, Frank-Pearce SG, Vidrine JI, Tahay PD, Marani SK, Chen S, Yuan Y, Cantor SB, Prokhorov AV. Efficacy of Mobile Phone-Delivered Smoking Cessation Interventions for Socioeconomically Disadvantaged Individuals: A Randomized Clinical Trial. JAMA Intern Med. 2019 Feb 1;179(2):167-174. doi: 10.1001/jamainternmed.2018.5713.

  • Daly AT, Deshmukh AA, Vidrine DJ, Prokhorov AV, Frank SG, Tahay PD, Houchen ME, Cantor SB. Cost-effectiveness analysis of smoking cessation interventions using cell phones in a low-income population. Tob Control. 2019 Jan;28(1):88-94. doi: 10.1136/tobaccocontrol-2017-054229. Epub 2018 Jun 9.

  • Vidrine DJ, Fletcher FE, Danysh HE, Marani S, Vidrine JI, Cantor SB, Prokhorov AV. A randomized controlled trial to assess the efficacy of an interactive mobile messaging intervention for underserved smokers: Project ACTION. BMC Public Health. 2012 Aug 25;12:696. doi: 10.1186/1471-2458-12-696.

MeSH Terms

Interventions

Smoking Devices

Intervention Hierarchy (Ancestors)

Manufactured MaterialsTechnology, Industry, and Agriculture

Study Officials

  • Alexander V Prokhorov

    M.D. Anderson Cancer Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 14, 2009

First Posted

July 29, 2009

Study Start

August 10, 2009

Primary Completion

February 10, 2021

Study Completion

February 10, 2021

Last Updated

January 20, 2023

Record last verified: 2023-01

Locations