NCT00852891

Brief Summary

The objective of this study was to analyze changes in cardiac function using Doppler echocardiogram in critical patients during weaning from mechanical ventilation using two different weaning methods (pressure support and T-tube) and to compare a subgroup of patients: success vs. failure in weaning and patients with vs. without heart disease.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
24

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Dec 2005

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2005

Completed
1.7 years until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2007

Completed
1.6 years until next milestone

First Submitted

Initial submission to the registry

February 26, 2009

Completed
1 day until next milestone

First Posted

Study publicly available on registry

February 27, 2009

Completed
Last Updated

February 27, 2009

Status Verified

February 1, 2009

First QC Date

February 26, 2009

Last Update Submit

February 26, 2009

Conditions

Critical CareWeaning

Keywords

weaningechocardiogramdiastolic dysfunctionMechanical ventilation

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients receiving MV for more than 48 hours, who had been admitted to the Intensive Care Unit (ICU), and who met the criteria for weaning from MV according to the parameters previously defined were selected to participate in this study.

You may qualify if:

  • patients hemodynamically stable
  • conscious (Glasgow scale ≥ 13)
  • with adequate gaseous exchange (O2 saturation ≥ 95%, fraction of inspired oxygen (FiO2) ≤ 40% and positive end-expiratory pressure (PEEP) = 5
  • with no acidosis or alkalosis)
  • normal electrolyte levels
  • presence of respiratory drive
  • informed consent was signed by the patients and/or family members

You may not qualify if:

  • hemodynamic instability
  • severe intracranial disease
  • barotrauma

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Federal University of Rio Grande do Sul

Porto Alegre, Rio Grande do Sul, Brazil

Location

Study Officials

  • Silvia RR Vieira, PhD

    Hospital de Clínicas de Porto Alegre

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

February 26, 2009

First Posted

February 27, 2009

Study Start

December 1, 2005

Study Completion

August 1, 2007

Last Updated

February 27, 2009

Record last verified: 2009-02

Locations

BR(1)