Effect of Swimming Exercise on Diastolic Dysfunction

NCT06945913 | Not Yet Recruiting

• 1 other identifier: UU-SBF-MBC-01
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the study was to determine the rehabilitative effects of 12-week variable intensity swimming exercises on the cardiovascular system in women with diastolic dysfunction. Studies on how variable intensity swimming exercises contribute to the course of the disease in sedentary women with cardiovascular problems are limited. Previous studies generally consisted of studies on the effects of exercise applications on the cardiovascular system in different branches and their effects were determined.

Conditions

Diastolic Dysfunction

Keywords

Diastolic Dysfunction; Exercise; High Intensity Interval Training; Moderate Intensity Continuous Training; Women Health

Outcome Measures

Primary Outcomes (6)

• Heart Rate Measurement by Electrocardiography

  Heart rate will be measured using a GE Healthcare MAC 2000 ECG device after 10 minutes of rest. Unit of Measure: Beats per minute (bpm)

  6 months

• P Wave Duration

  The duration of the P wave will be measured using standard 12-lead ECG recordings. Unit of Measure: Milliseconds (ms)

  6 months

• PR Interval

  The PR interval will be measured using standard 12-lead ECG recordings. Unit of Measure: Milliseconds (ms)

  6 months

• QRS Duration

  The QRS duration will be measured using standard 12-lead ECG recordings. Unit of Measure: Milliseconds (ms)

  6 months

• QT Interval

  The QT interval will be measured using standard 12-lead ECG recordings. Unit of Measure: Milliseconds (ms)

  6 months

• Corrected QT Interval (QTc)

  The corrected QT interval (QTc) will be measured using standard 12-lead ECG recordings. Unit of Measure: Milliseconds (ms)

  6 months

Secondary Outcomes (13)

• Cardiac Cavity Dimensions by Echocardiography

  6 months

• Interventricular Septal Thickness

  6 months

• Posterior Wall Thickness

  6 months

• Systolic Function - Ejection Fraction

  6 months

• Diastolic Function - Early Diastolic Filling Velocity (E)

  6 months

Study Arms (3)

HIIT Group

ACTIVE COMPARATOR

The first group (n=20) performed high-intensity interval training (HIIT) swimming exercises.

Behavioral: Exercise

MICT Group

SHAM COMPARATOR

The second group (n=20) performed moderate-intensity continuous training (MICT) swimming exercises.

Behavioral: Exercise

Non exercise Group

NO INTERVENTION

The control group (n=20) did not engage in any exercise intervention.

Interventions

Exercise BEHAVIORAL

HIIT Group

HIIT Group; MICT Group

Eligibility Criteria

• Age: 40 Years - 60 Years
• Gender Eligibility Details: Female
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Participants who met the following criteria were included in the study:
• No echocardiographic abnormalities detected except for stage 1 diastolic dysfunction based on examinations conducted in the cardiology outpatient clinic,
• Female gender,
• Aged between 40 and 60 years as of the study initiation date,
• No history of substance use, including smoking and alcohol,
• Willingness to participate by completing the informed consent form.

You may not qualify if:

• Participants who met at least one of the following conditions were excluded from the study:
• Refusal to sign the informed consent form,
• Failure to participate in at least one of the study measurements,
• Inability to meet the necessary criteria for training and measurements,
• Presence of illness or injury during training or measurements,
• Voluntary withdrawal from the study.

Sponsors & Collaborators

• Uşak University: lead

Study Sites (1)

Uşak U

Uşak, Merkez, 64100, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Motor Activity

Interventions

Exercise

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Central Study Contacts

Merve BOZ CİNCİ, Lecturer

CONTACT

+905533577475; mervebozcinci@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer

Model Details: The study was conducted with three groups: The first group (n=20) performed high-intensity interval training (HIIT) swimming exercises. The second group (n=20) performed moderate-intensity continuous training (MICT) swimming exercises. The control group (n=20) did not engage in any exercise intervention.

Study Record Dates

• First Submitted: March 10, 2025
• First Posted: April 27, 2025
• Study Start: May 1, 2025
• Primary Completion: July 10, 2025
• Study Completion: July 15, 2025
• Last Updated: April 27, 2025

Record last verified: 2025-04

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)