NCT00775021

Brief Summary

The objective of this study is to evaluate the clinical performance of two daily disposable contact lenses.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
123

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Aug 2008

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2008

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

October 15, 2008

Completed
2 days until next milestone

First Posted

Study publicly available on registry

October 17, 2008

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2009

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2009

Completed
2.2 years until next milestone

Results Posted

Study results publicly available

March 3, 2011

Completed
Last Updated

June 19, 2018

Status Verified

May 1, 2015

Enrollment Period

5 months

First QC Date

October 15, 2008

Results QC Date

February 7, 2011

Last Update Submit

June 18, 2018

Conditions

Outcome Measures

Primary Outcomes (1)

  • Overall Comfort

    Subjects rated study contact lens for overall comfort using the following scale: 5=excellent, 4=very good, 3=good, 2=fair, 1=poor.

    1 week

Secondary Outcomes (4)

  • Inferior Region Corneal Staining

    1 week

  • End of the Day Comfort

    1 week

  • Initial Comfort

    1 Week

  • Overall Lens Handling

    1 week

Study Arms (2)

etafilcon A/nelfilcon A

ACTIVE COMPARATOR

etafilcon A contact lens worn first and nelfilcon A contact lens worn second

Device: etafilcon ADevice: nelfilcon A

nelfilcon A/etafilcon A

ACTIVE COMPARATOR

nelfilcon A contact lens worn first and etafilcon A contact lens second.

Device: etafilcon ADevice: nelfilcon A

Interventions

Contact Lens

etafilcon A/nelfilcon Anelfilcon A/etafilcon A

Contact Lens

etafilcon A/nelfilcon Anelfilcon A/etafilcon A

Eligibility Criteria

Age18 Years - 45 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Age: 18 years to 45 years
  • Current daily soft contact lens as habitual optical correction:
  • Refraction:
  • Best sphere (corrected for back vertex distance) -1.00 to -6.00D
  • Cylinder 0.00 to - 0.75D
  • Best spectacle corrected visual acuity of 6/9 or better in each eye
  • Willingness to adhere to the instructions set in the clinical protocol
  • Signature of the subject on the informed consent form

You may not qualify if:

  • Systemic or ocular allergies which might interfere with contact lens wear
  • Systemic disease which might interfere with contact lens wear
  • Ocular disease which might interfere with contact lens wear (e.g. hypoesthesia, insufficient lacrimal secretion)
  • Use of medication which might interfere with contact lens wear
  • Active ocular infection
  • Use of ocular medication
  • Significant ocular anomaly
  • Presence of two or more corneal scars in either eye
  • Pregnancy or lactation
  • Any medical condition that might be prejudicial to the study
  • Participated in any other clinical studies in the past month
  • Currently wears monovision

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Otometry Technology Group, Ltd.

London, SW1E 6AU, United Kingdom

Location

MeSH Terms

Conditions

Myopia

Condition Hierarchy (Ancestors)

Refractive ErrorsEye Diseases

Results Point of Contact

Title
Kurt Moody, Director Design R&D
Organization
Vistakon

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 15, 2008

First Posted

October 17, 2008

Study Start

August 1, 2008

Primary Completion

January 1, 2009

Study Completion

January 1, 2009

Last Updated

June 19, 2018

Results First Posted

March 3, 2011

Record last verified: 2015-05

Locations