NCT00675454

Brief Summary

Emphysema is a lung disease that involves damage to the air sacs in the lungs and can lead to breathing difficulties. Treatment options for people with emphysema include pulmonary rehabilitation, lung volume reduction surgery, and lung transplantation. This study will observe people with emphysema to assess the effect of these treatment therapies on their quality of life and long-term health.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
802

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2000

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2000

Completed
8.4 years until next milestone

First Submitted

Initial submission to the registry

May 7, 2008

Completed
2 days until next milestone

First Posted

Study publicly available on registry

May 9, 2008

Completed
7.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 11, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 11, 2015

Completed
Last Updated

December 2, 2021

Status Verified

November 1, 2021

Enrollment Period

15.7 years

First QC Date

May 7, 2008

Last Update Submit

November 30, 2021

Conditions

Keywords

COPDLung Volume Reduction SurgeryLung TransplantQuality of Life

Eligibility Criteria

Age35 Years - 90 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Participants with moderate to severe emphysema who are undergoing pulmonary rehabilitation, lung volume reduction surgery, or lung transplantation.

You may qualify if:

  • Diagnosed with emphysema
  • Referred for pulmonary rehabilitation, lung volume reduction surgery, or lung transplantation

You may not qualify if:

  • Non-obstructive lung disease
  • Chronic obstructive pulmonary disease (COPD) that is not predominantly due to emphysema
  • Inability to read English

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Washington University School of Medicine and Barnes-Jewish Hospital

St Louis, Missouri, 63110, United States

Location

MeSH Terms

Conditions

Pulmonary Disease, Chronic ObstructiveEmphysema

Condition Hierarchy (Ancestors)

Lung Diseases, ObstructiveLung DiseasesRespiratory Tract DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Roger D. Yusen, MD, MPH

    Washington University School of Medicine, St. Louis

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 7, 2008

First Posted

May 9, 2008

Study Start

January 1, 2000

Primary Completion

September 11, 2015

Study Completion

September 11, 2015

Last Updated

December 2, 2021

Record last verified: 2021-11

Locations