SCCOR Minorities Observational Study

NCT02898272 | Completed

• 1 other identifier: PRO16040015
• Study Type: observational
• Target: 40
• Locations: 0 countries
• Sites: N/A

Brief Summary

The SCCOR Minorities study will recruit minority participants from the COPDGene cohort, in whom the University of Pittsburgh has already obtained baseline and five year data, in order to enhance bone mineral density and vascular function data collection from minority smokers. Dual X-ray absorptiometry (DXA) scans will be obtained to measure bone mineral density. Non-invasive vascular studies will be performed to measure endothelial function. Questionnaires regarding symptoms and activity levels will be administered and a blood sample will be obtained in participants in which blood samples are not already available from the COPDGene study visits.

Conditions

Pulmonary Disease, Chronic Obstructive; Emphysema

Outcome Measures

Primary Outcomes (1)

• Dual Xray Absorptiometry measurement of lumbar spine and hip bone mineral density.

  As this is a cross-sectional collection of data, the outcome will be measured once at the first and only study visit.

Secondary Outcomes (1)

• Measurement of carotid artery intimal thickness with ultrasound

  As this is a cross-sectional collection of data, the outcome will be measured once at the first and only study visit.

Eligibility Criteria

• Age: 45 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

\- African American male and female subjects participating in COPDGene study

You may qualify if:

• African American male and female subjects participating in COPDGene study

You may not qualify if:

• caucasians
• pregnant women

Sponsors & Collaborators

• University of Pittsburgh: lead

Biospecimen

Retention: SAMPLES WITH DNA

blood specimens will be obtained and stored for later analysis, which may include measurement of proteins, RNA expression, DNA.

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive; Emphysema

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: August 15, 2016
• First Posted: September 13, 2016
• Study Start: August 1, 2016
• Primary Completion: March 31, 2023
• Study Completion: March 31, 2023
• Last Updated: May 9, 2023

Record last verified: 2023-05