Key Insights

Highlights

Success Rate

88% trial completion (above average)

Published Results

36 trials with published results (17%)

Research Maturity

121 completed trials (57% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 40/100

Termination Rate

8.0%

17 terminated out of 212 trials

Success Rate

87.7%

+1.1% vs benchmark

Late-Stage Pipeline

15%

32 trials in Phase 3/4

Results Transparency

30%

36 of 121 completed with results

Key Signals

36 with results88% success17 terminated

Data Visualizations

Phase Distribution

136Total
Not Applicable (67)
Early P 1 (1)
P 1 (11)
P 2 (25)
P 3 (13)
P 4 (19)

Trial Status

Completed121
Unknown23
Recruiting23
Terminated17
Active Not Recruiting11
Withdrawn9

Trial Success Rate

87.7%

Benchmark: 86.6%

Based on 121 completed trials

Clinical Trials (212)

Showing 20 of 20 trials
NCT04932811Active Not Recruiting

The Lung Microbiome and Endobronchial Valve Treatment

NCT04930289Enrolling By Invitation

Global Utilization And Registry Database for Improved preservAtion of doNor LUNGs

NCT04186546Active Not RecruitingPrimary

Zephyr Valve Registry (ZEVR)

NCT06332885RecruitingPrimary

Zephyr Valve Japan Post-Marketing Surveillance

NCT04302272RecruitingPrimary

STRIVE Post-Market Registry Study

NCT07715617Recruiting

Development of a Prediction Score for the Occurrence of Death or Lung Transplantation in Patients With Emphysema Secondary to Alpha-1-anti-tripsin Deficiency

NCT07097896Not ApplicableRecruitingPrimary

Endobronchial Silicone Valve for Patients With Emphysema

NCT07682168Not ApplicableNot Yet Recruiting

DIVision of the Interlobar Fissure in Patients Who Do Not Respond to Endobronchial Lung Volume Reduction

NCT07086339Not ApplicableRecruiting

A Trial of the Implantable Artificial Bronchus 50 Flex in Patients With Severe Emphysema

NCT07119229Not ApplicableRecruiting

A Multi Center Study Testing a New Implant for Adults With Severe Emphysema

NCT07592637Not ApplicableNot Yet RecruitingPrimary

Lung Disease and FLNA Mutations

NCT06533371Not ApplicableRecruitingPrimary

Clinical-ultrasonographic Assessment of Pulmonary Emphysema

NCT07326592Phase 4Not Yet Recruiting

Phase 4, Double-blind Study Evaluating the Response on Computed Tomography (CT) Lung Density Decline Rates of Respreeza / Zemaira Weekly for 3 Years in Adults With alpha1 Antitrypsin Deficiency (AATD)

NCT05567562Phase 2Completed

Anti-Platelets in Chronic Obstructive Pulmonary Disease

NCT06025500RecruitingPrimary

Analysing Peripheral Skeletal Muscle Function Before and After Endobronchial Valve Treatment

NCT06891755Not ApplicableRecruiting

Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3

NCT00843271Active Not Recruiting

Endothelial Dysfunction, Biomarkers, and Lung Function -Ancillary to MESA

NCT05897424Phase 2Active Not Recruiting

Long-term, Open-label Study of SAR447537 (INBRX-101) in Adults With Alpha-1 Antitrypsin Deficiency Emphysema

NCT05087641Not ApplicableActive Not RecruitingPrimary

A Multicenter, Prospective Trial of the IAB in Adults Suffering From COPD/Emphysema

NCT05550844CompletedPrimary

Emphysema and FLNA Mutation (E-FLNA)

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