NCT00658996

Brief Summary

Product performance of a Bausch \& Lomb Toric Contact Lens compared to Ciba Vision Focus Daily Toric Contact Lens

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
220

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Apr 2008

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2008

Completed
11 days until next milestone

First Submitted

Initial submission to the registry

April 12, 2008

Completed
4 days until next milestone

First Posted

Study publicly available on registry

April 16, 2008

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2008

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2008

Completed
2.7 years until next milestone

Results Posted

Study results publicly available

February 16, 2011

Completed
Last Updated

December 12, 2011

Status Verified

December 1, 2011

Enrollment Period

2 months

First QC Date

April 12, 2008

Results QC Date

December 14, 2010

Last Update Submit

December 7, 2011

Conditions

Outcome Measures

Primary Outcomes (2)

  • Symptoms and Complaints

    1-100 Scale for each eye. Zero represented the least favorable rating and 100 represented the most favorable.

    Over-all follow-up visits for 2 week period

  • Contact Lens High Contrast Visual Acuity

    VA measures at each scheduled visit were averaged to obtain an overall measure for each eye. A non-inferiority upper bound of 0.06 (3 letters) were used to assess the difference (Test - Control) in overall logMAR VA.

    Over-all follow-up visits, 2 weeks

Secondary Outcomes (1)

  • Slit Lamp Findings

    Over-all follow-up visits, 2 weeks

Study Arms (2)

SofLens DD Toric

EXPERIMENTAL

Bausch \& Lomb SofLens Daily Disposable Toric Contact Lens

Device: SofLens DD Toric

Ciba Vision Toric Lens

ACTIVE COMPARATOR

Ciba Vision Focus Dailies Toric Contact Lens

Device: Ciba Vision Focus Dailies Toric Contact Lens

Interventions

daily disposable wear contact lens for 2 weeks

SofLens DD Toric

daily disposable wear contact lens for 2 weeks

Ciba Vision Toric Lens

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Subject is an adapted soft contact lens wearer with astigmatism of 0.50 Diopter or greater
  • Visual acuity (VA) correctable to 0.3 logMar or better (driving vision)
  • Clear central cornea

You may not qualify if:

  • Systemic disease affecting ocular health
  • Using systemic or topical medications
  • Wears monovision or multifocal contact lenses
  • Any grade 2 or greater slit lamp findings
  • Adapted wearer of Ciba Focus Dailies Toric lens upon study entry

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Laser Focus Sdn Bhd, Vision Correction Centre

Johor Bahru, 80400, Malaysia

Location

MeSH Terms

Conditions

MyopiaAstigmatism

Condition Hierarchy (Ancestors)

Refractive ErrorsEye Diseases

Results Point of Contact

Title
Gerard Cairns, PhD, MCOptom
Organization
Bausch & Lomb Incorporated

Study Officials

  • Gerard Cairns, PhD,MCOptom

    Bausch & Lomb Incorporated

    STUDY DIRECTOR
  • Benny Chian, MCOptom,DO

    Laser Focus Sdn Bhd, Vision Correction Centre

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
CROSSOVER
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 12, 2008

First Posted

April 16, 2008

Study Start

April 1, 2008

Primary Completion

June 1, 2008

Study Completion

June 1, 2008

Last Updated

December 12, 2011

Results First Posted

February 16, 2011

Record last verified: 2011-12

Locations