NCT01070381

Brief Summary

The purpose of this study is to investigate the subjective and objective performance of two daily disposable lenses for wearers with astigmatism.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
220

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jan 2010

Shorter than P25 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2010

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

February 16, 2010

Completed
2 days until next milestone

First Posted

Study publicly available on registry

February 18, 2010

Completed
11 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2010

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2010

Completed
1.1 years until next milestone

Results Posted

Study results publicly available

March 24, 2011

Completed
Last Updated

December 13, 2013

Status Verified

January 1, 2012

Enrollment Period

2 months

First QC Date

February 16, 2010

Results QC Date

February 25, 2011

Last Update Submit

November 19, 2013

Conditions

Outcome Measures

Primary Outcomes (1)

  • Overall Comfort

    Overall Comfort, as interpreted and reported by the participant on a questionnaire as a single, retrospective evaluation of 1-week's wear time. Overall comfort is measured on a 10-point scale, with 1 being poor and 10 being excellent.

    1 week of wear

Study Arms (2)

nelfilcon A / ocufilcon D

OTHER

Nelfilcon A contact lenses worn first, with ocufilcon D contact lenses worn second. Both products worn bilaterally on a daily wear, daily disposable basis for one week each.

Device: nelfilcon A contact lensDevice: ocufilcon D contact lens

ocufilcon D / nelfilcon A

OTHER

Ocufilcon D contact lenses worn first, with nelfilcon A contact lenses worn second. Both products worn bilaterally on a daily wear, daily disposable basis for one week each.

Device: nelfilcon A contact lensDevice: ocufilcon D contact lens

Interventions

Commercially marketed, toric, soft contact lens for daily disposable wear

nelfilcon A / ocufilcon Docufilcon D / nelfilcon A

Commercially marketed, toric, soft contact lens for daily disposable wear

nelfilcon A / ocufilcon Docufilcon D / nelfilcon A

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Current soft contact lens wearers able to be fit with soft toric lenses in the protocol-specified parameters.
  • Achieve 0.5 or better distance visual acuity in each eye at time of dispense.
  • Achieve acceptable or optimal fit in each eye at time of dispense.

You may not qualify if:

  • Habitual daily disposable contact lens wearer.
  • Sleeps in contact lenses overnight.
  • Currently enrolled in an ophthalmic clinical trial.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

MyopiaAstigmatism

Condition Hierarchy (Ancestors)

Refractive ErrorsEye Diseases

Results Point of Contact

Title
Priya Janakiraman, OD, FAAO / Head, Global Clinical Affairs
Organization
CIBA VISION

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 16, 2010

First Posted

February 18, 2010

Study Start

January 1, 2010

Primary Completion

March 1, 2010

Study Completion

March 1, 2010

Last Updated

December 13, 2013

Results First Posted

March 24, 2011

Record last verified: 2012-01