A Study of RO4607381 in Stable Coronary Heart Disease Patients With Recent Acute Coronary Syndrome
A Randomized, Double-blind, Placebo-controlled Study Assessing the Effect of RO4607381 on Cardiovascular Mortality and Morbidity in Clinically Stable Patients With a Recent Acute Coronary Syndrome
2 other identifiers
interventional
15,871
28 countries
1082
Brief Summary
This study will evaluate the potential of RO4607381 to reduce cardiovascular morbidity and mortality in stable coronary heart disease patients with recent Acute Coronary Syndrome (ACS) and evaluate the long term safety profile of the drug. Eligible patients in stable condition will be randomized to receive either RO4607381 600mg po or placebo po, daily, together with a background of standard medication for ACS (including aspirin, antihypertensives and statins). The anticipated time on study treatment is 2+ years, and the target sample size is 15,600 individuals.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for phase_3
Started Apr 2008
Typical duration for phase_3
1082 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
March 28, 2008
CompletedStudy Start
First participant enrolled
April 1, 2008
CompletedFirst Posted
Study publicly available on registry
April 15, 2008
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 1, 2012
CompletedStudy Completion
Last participant's last visit for all outcomes
September 1, 2012
CompletedResults Posted
Study results publicly available
January 3, 2020
CompletedJanuary 3, 2020
December 1, 2019
4.4 years
March 28, 2008
July 17, 2019
December 16, 2019
Conditions
Outcome Measures
Primary Outcomes (1)
Incidence of Cardiovascular Mortality and Morbidity
Number of cardiovascular events per patient per year
From date of randomization to first event up to 48 months
Secondary Outcomes (3)
Composite Endpoint:All Cause Mortality
Throughout Study, up to 53 Months
Change From Baseline for HDL Cholesterol
At 53 Months
Adverse Events, Lab Parameters, Vital Signs, ECG
Throughout Study, up to 53 Months
Study Arms (2)
Dalcetrapib (RO4607381)
EXPERIMENTALPlacebo
PLACEBO COMPARATORInterventions
As prescribed
Eligibility Criteria
You may qualify if:
- adult patients, \>=45 years of age;
- recently hospitalized for ACS;
- clinically stable;
- receiving evidence-based medical and dietary management of dyslipidemia.
You may not qualify if:
- uncontrolled diabetes;
- clinically unstable;
- severe anemia;
- uncontrolled hypertension;
- concomitant treatment with any other drug raising HDL-C (eg niacin, fibrates).
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1089)
Unknown Facility
Birmingham, Alabama, 35213, United States
Unknown Facility
Birmingham, Alabama, 35215, United States
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Birmingham, Alabama, 35235, United States
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Birmingham, Alabama, 35294, United States
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Mobile, Alabama, 36688, United States
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Tuscaloosa, Alabama, 35406, United States
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Lake Havasu City, Arizona, 86403, United States
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Mesa, Arizona, 85206, United States
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Phoenix, Arizona, 85006, United States
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Phoenix, Arizona, 85015, United States
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Scottsdale, Arizona, 85025, United States
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Scottsdale, Arizona, 85258, United States
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Sierra Vista, Arizona, 85635, United States
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Tempe, Arizona, 85283, United States
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Tucson, Arizona, 85715, United States
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Hot Springs, Arkansas, 71913, United States
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Jonesboro, Arkansas, 72401, United States
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Little Rock, Arkansas, 72204, United States
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Mountain Home, Arkansas, 72653, United States
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Searcy, Arkansas, 72143, United States
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Anaheim, California, 92801, United States
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Bakersfield, California, 93308, United States
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Bellflower, California, 90706, United States
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Beverly Hills, California, 90210, United States
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Buena Park, California, 90621, United States
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Burbank, California, 91505-4866, United States
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Carmichael, California, 95608, United States
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Corona, California, 92879, United States
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Costa Mesa, California, 92626, United States
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Encinitas, California, 92024, United States
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Fountain Valley, California, 92708, United States
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Fresno, California, 93720, United States
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Fresno, California, 93721, United States
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Fullerton, California, 92835, United States
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Glendale, California, 91204, United States
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Glendale, California, 91206, United States
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Hawaiian Gardens, California, 90716, United States
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Hollywood, California, 90028, United States
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Inglewood, California, 90301, United States
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La Jolla, California, 92093, United States
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La Mesa, California, 91942, United States
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Laguna Hills, California, 92653, United States
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Loma Linda, California, 92354, United States
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Lomita, California, 90717, United States
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Long Beach, California, 90822, United States
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Los Alamitos, California, 90720, United States
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Los Angeles, California, 90015, United States
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Los Angeles, California, 90034, United States
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Los Angeles, California, 90036, United States
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Los Angeles, California, 90048, United States
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Los Banos, California, 93635, United States
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Mather, California, 95655, United States
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Mission Viejo, California, 92691, United States
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Mountain View, California, 94040, United States
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Newport Beach, California, 92660, United States
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Newport Beach, California, 92663, United States
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Pasadena, California, 91105, United States
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Pomona, California, 91767, United States
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Redondo Beach, California, 90277, United States
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Sacramento, California, 95816, United States
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Sacramento, California, 95819, United States
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Sacramento, California, 95825, United States
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San Diego, California, 92103, United States
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San Diego, California, 92120, United States
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San Diego, California, 92121, United States
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San Dimas, California, 91773, United States
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San Francisco, California, 94115, United States
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San Francisco, California, 94118, United States
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San Jose, California, 95119, United States
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Santa Ana, California, 92704, United States
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Santa Rosa, California, 95405, United States
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Simi Valley, California, 91204, United States
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Stockton, California, 95207, United States
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Stockton, California, 95210, United States
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Thousand Oaks, California, 91360, United States
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Torrance, California, 90502, United States
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Whittier, California, 90606, United States
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Colorado Springs, Colorado, 80907, United States
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Colorado Springs, Colorado, 80909, United States
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Denver, Colorado, 80218, United States
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Denver, Colorado, 80220, United States
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Greeley, Colorado, 80631, United States
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Littleton, Colorado, 80120, United States
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Loveland, Colorado, 80538, United States
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Pueblo, Colorado, 81003, United States
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Bridgeport, Connecticut, 06606, United States
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Danbury, Connecticut, 06810, United States
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Guilford, Connecticut, 06437, United States
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Hartford, Connecticut, 06115, United States
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Stamford, Connecticut, 06905, United States
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Washington D.C., District of Columbia, 20010, United States
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Washington D.C., District of Columbia, 20037, United States
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Aventura, Florida, 33180, United States
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Boynton Beach, Florida, 33472, United States
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Chipley, Florida, 32428, United States
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Clearwater, Florida, 33756, United States
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Clearwater, Florida, 33764, United States
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Crystal River, Florida, 34429, United States
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Daytona Beach, Florida, 32114, United States
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Daytona Beach, Florida, 32117, United States
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Deerfield Beach, Florida, 33442, United States
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Delray Beach, Florida, 33445, United States
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Delray Beach, Florida, 33484, United States
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Elizabeth, Florida, 07202, United States
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Fort Lauderdale, Florida, 33316, United States
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Gainesville, Florida, 32605, United States
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Gainesville, Florida, 32608, United States
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Gainesville, Florida, 32610-0277, United States
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Hollywood, Florida, 33021, United States
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Hudson, Florida, 34667, United States
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Jacksonville, Florida, 32207, United States
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Jacksonville, Florida, 32216, United States
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Jacksonville, Florida, 32224, United States
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Jacksonville Beach, Florida, 32250, United States
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Jupiter, Florida, 33458, United States
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Kissimmee, Florida, 34741, United States
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Lakeland, Florida, 33805, United States
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Marianna, Florida, 32446, United States
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Melbourne, Florida, 32901, United States
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Miami, Florida, 33136, United States
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Miami, Florida, 33137, United States
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Miami, Florida, 33186, United States
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Ocala, Florida, 34474, United States
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Orlando, Florida, 32803, United States
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Panama City, Florida, 32401, United States
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Pensacola, Florida, 32501, United States
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Pensacola, Florida, 32504, United States
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Plantation, Florida, 33317, United States
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Port Charlotte, Florida, 33952, United States
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Safety Harbor, Florida, 34695, United States
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Sarasota, Florida, 34239, United States
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St. Petersburg, Florida, 33701, United States
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St. Petersburg, Florida, 33709, United States
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Tallahassee, Florida, 32308, United States
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Tamarac, Florida, 33321, United States
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Tampa, Florida, 33609, United States
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Tampa, Florida, 33612, United States
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Tampa, Florida, 33613, United States
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Tampa, Florida, 33624, United States
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West Palm Beach, Florida, 33401, United States
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West Palm Beach, Florida, 33407, United States
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Atlanta, Georgia, 30303, United States
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Atlanta, Georgia, 30308, United States
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Atlanta, Georgia, 30309, United States
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Atlanta, Georgia, 30312, United States
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Atlanta, Georgia, 30318, United States
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Atlanta, Georgia, 30322, United States
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Atlanta, Georgia, 30342, United States
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Columbus, Georgia, 31904, United States
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Covington, Georgia, 30014, United States
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Decatur, Georgia, 30033, United States
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Monroe, Georgia, 30655, United States
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Riverdale, Georgia, 30274, United States
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Savannah, Georgia, 31406, United States
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Tucker, Georgia, 33084, United States
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Waycross, Georgia, 31501, United States
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Honolulu, Hawaii, 96813, United States
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Boise, Idaho, 83712, United States
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Aurora, Illinois, 60504, United States
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Bannockburn, Illinois, 60015, United States
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Chicago, Illinois, 60616, United States
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Evanston, Illinois, 60202, United States
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Gurnee, Illinois, 60031, United States
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Hinsdale, Illinois, 60521, United States
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Joliet, Illinois, 60435, United States
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Libertyville, Illinois, 60048, United States
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Melrose Park, Illinois, 60160, United States
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Mokena, Illinois, 60448, United States
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Naperville, Illinois, 60566-7266, United States
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Normal, Illinois, 61761, United States
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Peoria, Illinois, 61606, United States
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Peoria, Illinois, 61614, United States
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Rockford, Illinois, 61107, United States
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Winfield, Illinois, 60190, United States
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Anderson, Indiana, 46060, United States
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Elkhart, Indiana, 46514, United States
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Evansville, Indiana, 47710, United States
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Fishers, Indiana, 46038, United States
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Fort Wayne, Indiana, 46805, United States
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Franklin, Indiana, 46131, United States
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Greenfield, Indiana, 46140, United States
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Hammond, Indiana, 46320-1942, United States
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Indianapolis, Indiana, 46202, United States
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Indianapolis, Indiana, 46237, United States
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Indianapolis, Indiana, 46250, United States
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Indianapolis, Indiana, 46254, United States
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Indianapolis, Indiana, 46260, United States
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Merrillville, Indiana, 46410, United States
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Munster, Indiana, 46321, United States
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South Bend, Indiana, 46601, United States
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Ames, Iowa, 50010, United States
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Council Bluffs, Iowa, 51501, United States
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Davenport, Iowa, 52803, United States
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Waterloo, Iowa, 50702, United States
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Olathe, Kansas, 66061, United States
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Overland Park, Kansas, 66209, United States
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Elizabethtown, Kentucky, 42701, United States
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Hazard, Kentucky, 41701, United States
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Lexington, Kentucky, 40503, United States
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Lexington, Kentucky, 40504, United States
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Lexington, Kentucky, 40536, United States
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Louisville, Kentucky, 40202, United States
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Louisville, Kentucky, 40207, United States
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Madisonville, Kentucky, 42431, United States
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Owensboro, Kentucky, 42303, United States
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Alexandria, Louisiana, 71301, United States
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Lake Charles, Louisiana, 70601, United States
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Marrero, Louisiana, 70072, United States
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Metairie, Louisiana, 70006, United States
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Natchitoches, Louisiana, 71457, United States
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New Orleans, Louisiana, 70112, United States
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New Orleans, Louisiana, 70115, United States
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Shreveport, Louisiana, 71103, United States
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Slidell, Louisiana, 70458, United States
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West Monroe, Louisiana, 71291, United States
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Bangor, Maine, 04401, United States
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Biddeford, Maine, 04005, United States
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Portland, Maine, 04101, United States
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Scarborough, Maine, 04074, United States
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South Portland, Maine, 4106, United States
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Baltimore, Maryland, 21201, United States
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Baltimore, Maryland, 21202, United States
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Baltimore, Maryland, 21218, United States
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Baltimore, Maryland, 21229, United States
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Baltimore, Maryland, 21237, United States
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Baltimore, Maryland, 21239, United States
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Bel Air, Maryland, 21014, United States
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Columbia, Maryland, 21044, United States
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Hagerstown, Maryland, 21740, United States
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Pikesville, Maryland, 21208, United States
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Salisbury, Maryland, 21804, United States
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Towson, Maryland, 21157, United States
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Towson, Maryland, 21204, United States
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Westminster, Maryland, 21157, United States
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Billerica, Massachusetts, 01821, United States
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Boston, Massachusetts, 02114, United States
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Boston, Massachusetts, 02215, United States
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East Bridgewater, Massachusetts, 02333, United States
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Haverhill, Massachusetts, 01830, United States
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Hyannis, Massachusetts, 02601, United States
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Natick, Massachusetts, 01760, United States
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North Dartmouth, Massachusetts, 02747, United States
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Pittsfield, Massachusetts, 01201, United States
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Springfield, Massachusetts, 01199, United States
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Taunton, Massachusetts, 02780, United States
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Worcester, Massachusetts, 01604, United States
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Worcester, Massachusetts, 01655, United States
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Alpena, Michigan, 49707, United States
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Ann Arbor, Michigan, 48105, United States
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Bloomfield, Michigan, 48302, United States
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Cadillac, Michigan, 49601, United States
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Dearborn, Michigan, 48124, United States
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Detroit, Michigan, 48221, United States
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Detroit, Michigan, 48235, United States
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Fairfield, Michigan, 45014, United States
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Flint, Michigan, 48504, United States
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Flint, Michigan, 48532, United States
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Kalamazoo, Michigan, 49007, United States
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Kalamazoo, Michigan, 49048, United States
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Lansing, Michigan, 48909, United States
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Lansing, Michigan, 48910, United States
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Midland, Michigan, 48670, United States
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Milwaukee, Michigan, 53295, United States
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Petoskey, Michigan, 49770, United States
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Rochester Hills, Michigan, 48307, United States
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Saginaw, Michigan, 48602, United States
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Saint Joseph, Michigan, 49085, United States
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Chaska, Minnesota, 55318, United States
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Duluth, Minnesota, 55802, United States
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Duluth, Minnesota, 55805, United States
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Minneapolis, Minnesota, 55417, United States
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Minneapolis, Minnesota, 55433, United States
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Minneapolis, Minnesota, 55455, United States
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Robbinsdale, Minnesota, 55422, United States
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Rochester, Minnesota, 55905, United States
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Saint Cloud, Minnesota, 56303, United States
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Saint Paul, Minnesota, 55102, United States
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Gulfport, Mississippi, 39503, United States
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Jackson, Mississippi, 39216, United States
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Picayune, Mississippi, 39466, United States
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Tupelo, Mississippi, 38803, United States
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Columbia, Missouri, 65201, United States
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Kansas City, Missouri, 64111, United States
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St Louis, Missouri, 63110, United States
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St Louis, Missouri, 63128, United States
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Billings, Montana, 59101, United States
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Great Falls, Montana, 59405, United States
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Kalispell, Montana, 59901, United States
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Missoula, Montana, 59802, United States
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Fremont, Nebraska, 68025, United States
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Grand Island, Nebraska, 68803, United States
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Lincoln, Nebraska, 68506, United States
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Omaha, Nebraska, 68131, United States
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Papillion, Nebraska, 68046, United States
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Las Vegas, Nevada, 89102, United States
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Las Vegas, Nevada, 89128, United States
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Reno, Nevada, 89502, United States
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Manchester, New Hampshire, 03102, United States
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Nashua, New Hampshire, 03060, United States
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Bridgewater, New Jersey, 08807, United States
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Clifton, New Jersey, 07012, United States
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East Orange, New Jersey, 07018, United States
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Edgewater, New Jersey, 07020, United States
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Elmer, New Jersey, 08318, United States
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Greenville, New Jersey, 29605, United States
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Hackensack, New Jersey, 07601, United States
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Haddon Heights, New Jersey, 08035, United States
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Hawthorne, New Jersey, 07506, United States
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Linden, New Jersey, 07036, United States
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Mine Hill, New Jersey, 07803, United States
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New Brunswick, New Jersey, 08901, United States
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Newark, New Jersey, 07103, United States
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Ridgewood, New Jersey, 07450, United States
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Sewell, New Jersey, 08080, United States
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Somerset, New Jersey, 8873, United States
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Summit, New Jersey, 07901, United States
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Toms River, New Jersey, 08755, United States
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Voorhees Township, New Jersey, 08043, United States
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Westwood, New Jersey, 07675, United States
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Albuquerque, New Mexico, 87131, United States
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Albany, New York, 12211, United States
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Brooklyn, New York, 11201, United States
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Brooklyn, New York, 11203, United States
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Brooklyn, New York, 11212, United States
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Brooklyn, New York, 11229, United States
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Buffalo, New York, 14203, United States
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Buffalo, New York, 14215, United States
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Fishkill, New York, 12524, United States
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Flushing, New York, 11355, United States
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Johnson City, New York, 13790, United States
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Liverpool, New York, 13088, United States
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New Hartford, New York, 13413, United States
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New Windsor, New York, 12553, United States
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New York, New York, 10021, United States
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New York, New York, 10025, United States
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New York, New York, 10029, United States
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New York, New York, 10032, United States
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Poughkeepsie, New York, 12601, United States
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Rochester, New York, 14618, United States
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Rochester, New York, 14642, United States
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Saratoga Springs, New York, 12866, United States
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Springfield Gardens, New York, 11413, United States
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Stony Brook, New York, 11794, United States
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Suffern, New York, 10901-5204, United States
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Syracuse, New York, 13210, United States
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The Bronx, New York, 10461, United States
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The Bronx, New York, 10463, United States
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Troy, New York, 12180, United States
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West Seneca, New York, 14224, United States
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Asheville, North Carolina, 28803, United States
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Cary, North Carolina, 27511, United States
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Chapel Hill, North Carolina, 27599, United States
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Charlotte, North Carolina, 28203, United States
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Charlotte, North Carolina, 28204, United States
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Concord, North Carolina, 28025, United States
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Durham, North Carolina, 27704, United States
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Durham, North Carolina, 27710, United States
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Elizabeth City, North Carolina, 27909, United States
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Pinehurst, North Carolina, 28374, United States
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Rocky Mount, North Carolina, 27804, United States
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Salt Lake City, North Carolina, 84124-1236, United States
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Tabor City, North Carolina, 28463, United States
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Wilmington, North Carolina, 28401, United States
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Winston-Salem, North Carolina, 27103, United States
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Fargo, North Dakota, 58103, United States
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Minot, North Dakota, 58701, United States
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Akron, Ohio, 44304, United States
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Akron, Ohio, 44307, United States
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Athens, Ohio, 45701, United States
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Canton, Ohio, 44708, United States
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Centerville, Ohio, 45459, United States
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Cincinnati, Ohio, 45203-0542, United States
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Cincinnati, Ohio, 45219, United States
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Cleveland, Ohio, 44195, United States
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Columbus, Ohio, 43235, United States
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Kettering, Ohio, 45429, United States
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Mansfield, Ohio, 44827, United States
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Marion, Ohio, 43302, United States
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Mentor, Ohio, 44060, United States
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Middletown, Ohio, 45005, United States
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Sandusky, Ohio, 44870, United States
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Springfield, Ohio, 45505, United States
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Thornville, Ohio, 43076, United States
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Toledo, Ohio, 43606, United States
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Toledo, Ohio, 43608, United States
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Toledo, Ohio, 43623, United States
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Westlake, Ohio, 44145, United States
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Willoughby Hills, Ohio, 44094, United States
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Zanesville, Ohio, 43701, United States
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Bartlesville, Oklahoma, 74006, United States
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Midwest City, Oklahoma, 73110, United States
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Oklahoma City, Oklahoma, 73103, United States
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Oklahoma City, Oklahoma, 73104, United States
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Oklahoma City, Oklahoma, 73109, United States
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Bend, Oregon, 97701, United States
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Portland, Oregon, 97232, United States
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Abington, Pennsylvania, 19001, United States
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Allentown, Pennsylvania, 18105, United States
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Altoona, Pennsylvania, 16602, United States
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Beaver, Pennsylvania, 15009, United States
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Bryn Mawr, Pennsylvania, 19010-3121, United States
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Camp Hill, Pennsylvania, 17011, United States
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Downingtown, Pennsylvania, 19335, United States
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Doylestown, Pennsylvania, 18901, United States
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Easton, Pennsylvania, 18042, United States
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Erie, Pennsylvania, 16502, United States
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Feasterville, Pennsylvania, 19053, United States
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Havertown, Pennsylvania, 19083, United States
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Hershey, Pennsylvania, 17033, United States
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Lancaster, Pennsylvania, 17603, United States
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Langhorne, Pennsylvania, 19047, United States
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Limerick, Pennsylvania, 19468, United States
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Natrona Heights, Pennsylvania, 15065, United States
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North Wales, Pennsylvania, 19454, United States
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Philadelphia, Pennsylvania, 19104, United States
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Philadelphia, Pennsylvania, 19106, United States
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Philadelphia, Pennsylvania, 19107, United States
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Pittsburgh, Pennsylvania, 15212, United States
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Pittsburgh, Pennsylvania, 15213, United States
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Pittsburgh, Pennsylvania, 15241, United States
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Pottstown, Pennsylvania, 19464, United States
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Sayre, Pennsylvania, 18840, United States
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Scranton, Pennsylvania, 18503, United States
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Sellersville, Pennsylvania, 18960, United States
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West Chester, Pennsylvania, 19380, United States
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Wormleysburg, Pennsylvania, 17043, United States
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Wynnewood, Pennsylvania, 19096, United States
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Wyomissing, Pennsylvania, 19610, United States
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Providence, Rhode Island, 02904, United States
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Providence, Rhode Island, 02906, United States
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Wakefield, Rhode Island, 02879, United States
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Aiken, South Carolina, 29801, United States
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Charleston, South Carolina, 29406, United States
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Charleston, South Carolina, 29425, United States
Unknown Facility
Columbia, South Carolina, 29204, United States
Unknown Facility
Greer, South Carolina, 29651, United States
Unknown Facility
Moncks Corner, South Carolina, 29461, United States
Unknown Facility
Spartanburg, South Carolina, 29302, United States
Unknown Facility
Spartanburg, South Carolina, 29303, United States
Unknown Facility
Taylors, South Carolina, 29687, United States
Unknown Facility
Knoxville, South Dakota, 37920, United States
Unknown Facility
Rapid City, South Dakota, 57701, United States
Unknown Facility
Sioux Falls, South Dakota, 57104, United States
Unknown Facility
Bristol, Tennessee, 37620, United States
Unknown Facility
Jackson, Tennessee, 38301, United States
Unknown Facility
Johnson City, Tennessee, 37604, United States
Unknown Facility
Kingsport, Tennessee, 37660, United States
Unknown Facility
Knoxville, Tennessee, 37917, United States
Unknown Facility
Knoxville, Tennessee, 37920, United States
Unknown Facility
Lexington, Tennessee, 38351, United States
Unknown Facility
Oak Ridge, Tennessee, 37830, United States
Unknown Facility
Austin, Texas, 78666, United States
Unknown Facility
Austin, Texas, 78756, United States
Unknown Facility
Dallas, Texas, 75216, United States
Unknown Facility
Dallas, Texas, 75230, United States
Unknown Facility
Dallas, Texas, 75231, United States
Unknown Facility
Dallas, Texas, 75243, United States
Unknown Facility
Dallas, Texas, 75390, United States
Unknown Facility
Fort Worth, Texas, 76107, United States
Unknown Facility
Houston, Texas, 77005, United States
Unknown Facility
Houston, Texas, 77030, United States
Unknown Facility
Houston, Texas, 77070, United States
Unknown Facility
Houston, Texas, 77090, United States
Unknown Facility
Humble, Texas, 77338, United States
Unknown Facility
Killeen, Texas, 76549, United States
Unknown Facility
Lubbock, Texas, 79410, United States
Unknown Facility
Odessa, Texas, 79761, United States
Unknown Facility
Plano, Texas, 75024, United States
Unknown Facility
Round Rock, Texas, 78681, United States
Unknown Facility
San Antonio, Texas, 78205, United States
Unknown Facility
San Antonio, Texas, 78217, United States
Unknown Facility
Tomball, Texas, 77375, United States
Unknown Facility
Tyler, Texas, 75701, United States
Unknown Facility
Tyler, Texas, 75708, United States
Unknown Facility
Victoria, Texas, 77901, United States
Unknown Facility
Layton, Utah, 84041, United States
Unknown Facility
Provo, Utah, 84004, United States
Unknown Facility
Burke, Virginia, 22015, United States
Unknown Facility
Charlottesville, Virginia, 22908, United States
Unknown Facility
Colonial Heights, Virginia, 23834, United States
Unknown Facility
Danville, Virginia, 24541-4160, United States
Unknown Facility
Danville, Virginia, 24541, United States
Unknown Facility
Falls Church, Virginia, 22042, United States
Unknown Facility
Falls Church, Virginia, 22044, United States
Unknown Facility
Galax, Virginia, 24333, United States
Unknown Facility
Hopewell, Virginia, 23860, United States
Unknown Facility
Manassas, Virginia, 20109, United States
Unknown Facility
Midlothian, Virginia, 23114, United States
Unknown Facility
Norfolk, Virginia, 23507-1901, United States
Unknown Facility
Norfolk, Virginia, 23510, United States
Unknown Facility
Richmond, Virginia, 23226, United States
Unknown Facility
Richmond, Virginia, 23249, United States
Unknown Facility
Roanoke, Virginia, 24104, United States
Unknown Facility
Salem, Virginia, 24019, United States
Unknown Facility
Springfield, Virginia, 22151, United States
Unknown Facility
Winchester, Virginia, 22601, United States
Unknown Facility
Bellevue, Washington, 98004, United States
Unknown Facility
Everett, Washington, 98201, United States
Unknown Facility
Monroe, Washington, 98272, United States
Unknown Facility
Selah, Washington, United States
Unknown Facility
Spokane, Washington, 99204, United States
Unknown Facility
Clarksburg, West Virginia, 26301, United States
Unknown Facility
Beloit, Wisconsin, 53511, United States
Unknown Facility
Burlington, Wisconsin, 53105, United States
Unknown Facility
Green Bay, Wisconsin, 54301, United States
Unknown Facility
Green Bay, Wisconsin, 54303, United States
Unknown Facility
La Crosse, Wisconsin, 54601-4795, United States
Unknown Facility
Madison, Wisconsin, 53713, United States
Unknown Facility
Madison, Wisconsin, 53715, United States
Unknown Facility
Madison, Wisconsin, 53792, United States
Unknown Facility
Marshfield, Wisconsin, 54449, United States
Unknown Facility
Milwaukee, Wisconsin, 53215, United States
Unknown Facility
Milwaukee, Wisconsin, 53226, United States
Unknown Facility
Almirante Brown, B1846DSK, Argentina
Unknown Facility
Bahía Blanca, B8000ILD, Argentina
Unknown Facility
Buenos Aires, 1039, Argentina
Unknown Facility
Buenos Aires, 1428, Argentina
Unknown Facility
Buenos Aires, 1431, Argentina
Unknown Facility
Buenos Aires, 1708, Argentina
Unknown Facility
Buenos Aires, 1722, Argentina
Unknown Facility
Buenos Aires, B1605DSX, Argentina
Unknown Facility
Buenos Aires, B2800JIR, Argentina
Unknown Facility
Buenos Aires, B7600FZN, Argentina
Unknown Facility
Buenos Aires, C1426ANZ, Argentina
Unknown Facility
Buenos Aires, C1437JCP, Argentina
Unknown Facility
Buenos Aires, Argentina
Unknown Facility
CABA, C1428DCO, Argentina
Unknown Facility
Capital Federal, C1093AAS, Argentina
Unknown Facility
Cipolletti, 8324, Argentina
Unknown Facility
Ciudad Autonoma Bs As, C1280AEB, Argentina
Unknown Facility
Ciudad Autónoma de Bs. As., C1437BZK, Argentina
Unknown Facility
Coronel Suárez, B7540GDH, Argentina
Unknown Facility
Corrientes, W3400AMZ, Argentina
Unknown Facility
Córdoba, 5016, Argentina
Unknown Facility
Córdoba, X5000AAC, Argentina
Unknown Facility
Córdoba, X5000JHQ, Argentina
Unknown Facility
Junín, B6000CMF, Argentina
Unknown Facility
La Plata, 1725, Argentina
Unknown Facility
Mar del Plata, 7600, Argentina
Unknown Facility
Mar del Plata, B7600FEN, Argentina
Unknown Facility
Mendoza, 5500, Argentina
Unknown Facility
Quilmes, 1878, Argentina
Unknown Facility
Rosario, 2000, Argentina
Unknown Facility
Rosario, S2000CVD, Argentina
Unknown Facility
Salta, A4406CLA, Argentina
Unknown Facility
San Isidro, B1642AKG, Argentina
Unknown Facility
San Justo, 1754, Argentina
Unknown Facility
San Martín, 1650, Argentina
Unknown Facility
San Miguel de Tucumán, 4000, Argentina
Unknown Facility
San Salvador de Jujuy, Y4600ABF, Argentina
Unknown Facility
Santa Fe, 3000, Argentina
Unknown Facility
Garran, Australian Capital Territory, 2605, Australia
Unknown Facility
Coffs Harbour, New South Wales, 2450, Australia
Unknown Facility
Concord, New South Wales, 2137, Australia
Unknown Facility
Epping, New South Wales, 3076, Australia
Unknown Facility
Kingswood, New South Wales, 2747, Australia
Unknown Facility
Wollongong, New South Wales, 2500, Australia
Unknown Facility
Cairns, Queensland, 4870, Australia
Unknown Facility
Chermside, Queensland, 4032, Australia
Unknown Facility
Milton, Queensland, 4064, Australia
Unknown Facility
Woolloongabba, Queensland, 4102, Australia
Unknown Facility
Bedford Park, South Australia, 5042, Australia
Unknown Facility
Box Hill, Victoria, 3128, Australia
Unknown Facility
Geelong, Victoria, 3220, Australia
Unknown Facility
Sale, Victoria, 3850, Australia
Unknown Facility
Joondalup, Western Australia, 6027, Australia
Unknown Facility
Nedlands, Western Australia, 6009, Australia
Unknown Facility
Feldkirch, 6807, Austria
Unknown Facility
Graz, 8020, Austria
Unknown Facility
Graz, 8036, Austria
Unknown Facility
Linz, 4010, Austria
Unknown Facility
Vienna, 1090, Austria
Unknown Facility
Vienna, 1100, Austria
Unknown Facility
Vienna, 1140, Austria
Unknown Facility
Aalst, 9300, Belgium
Unknown Facility
Bruges, 8000, Belgium
Unknown Facility
Brussels, 1180, Belgium
Unknown Facility
Brussels, 1200, Belgium
Unknown Facility
Genk, 3600, Belgium
Unknown Facility
Ghent, 9000, Belgium
Unknown Facility
La Louvière, 7100, Belgium
Unknown Facility
Roeselare, 8800, Belgium
Unknown Facility
Tienen, 3300, Belgium
Unknown Facility
Maceió, Alagoas, 57051500, Brazil
Unknown Facility
Fortaleza, Ceará, 60840285, Brazil
Unknown Facility
Salvador, Estado de Bahia, 40140000, Brazil
Unknown Facility
Goiânia, Goiás, 74223-130, Brazil
Unknown Facility
Campo Grande, Mato Grosso do Sul, 79070900, Brazil
Unknown Facility
Belo Horizonte, Minas Gerais, 30110-068, Brazil
Unknown Facility
Belo Horizonte, Minas Gerais, 30140092, Brazil
Unknown Facility
Belo Horizonte, Minas Gerais, 30190-081, Brazil
Unknown Facility
Belo Horizonte, Minas Gerais, 30190-130, Brazil
Unknown Facility
Belo Horizonte, Minas Gerais, 31110-580, Brazil
Unknown Facility
Uberlândia, Minas Gerais, 38400-368, Brazil
Unknown Facility
Campina Grande do Sul, Paraná, 83430-000, Brazil
Unknown Facility
Curitiba, Paraná, 80220-000, Brazil
Unknown Facility
Curitiba, Paraná, 80730150, Brazil
Unknown Facility
Olinda, Pernambuco, 53030-010, Brazil
Unknown Facility
Recife, Pernambuco, 50100-060, Brazil
Unknown Facility
Recife, Pernambuco, 52051-380, Brazil
Unknown Facility
Rio de Janeiro, Rio de Janeiro, 20221903, Brazil
Unknown Facility
Rio de Janeiro, Rio de Janeiro, 20551030, Brazil
Unknown Facility
Rio de Janeiro, Rio de Janeiro, 22240-006, Brazil
Unknown Facility
Natal, Rio Grande do Norte, 59020-100, Brazil
Unknown Facility
Pelotas, Rio Grande do Sul, 96015-290, Brazil
Unknown Facility
Porto Alegre, Rio Grande do Sul, 90020-090, Brazil
Unknown Facility
Porto Alegre, Rio Grande do Sul, 90035-003, Brazil
Unknown Facility
Porto Alegre, Rio Grande do Sul, 90110-270, Brazil
Unknown Facility
Porto Alegre, Rio Grande do Sul, 90610-000, Brazil
Unknown Facility
Porto Alegre, Rio Grande do Sul, 90620-001, Brazil
Unknown Facility
Sao Jose Do Rio Preto, Santa Catarina, 15015-210, Brazil
Unknown Facility
Sao Jose Do Rio Preto, Santa Catarina, 15015205, Brazil
Unknown Facility
Aracaju, Sergipe, 49015400, Brazil
Unknown Facility
Campinas, São Paulo, 13060-803, Brazil
Unknown Facility
Ribeirão Preto, São Paulo, 14048-900, Brazil
Unknown Facility
Santo André, São Paulo, 9190610, Brazil
Unknown Facility
São José do Rio Preto, São Paulo, 15090-000, Brazil
Unknown Facility
São Paulo, São Paulo, 01323-020, Brazil
Unknown Facility
São Paulo, São Paulo, 01323-030, Brazil
Unknown Facility
São Paulo, São Paulo, 04012909, Brazil
Unknown Facility
São Paulo, São Paulo, 05403-000, Brazil
Unknown Facility
São Paulo, São Paulo, 22793-080, Brazil
Unknown Facility
Calgary, Alberta, T2E 7C5, Canada
Unknown Facility
Edmonton, Alberta, T5H 3V9, Canada
Unknown Facility
Edmonton, Alberta, T6K 4C1, Canada
Unknown Facility
Nanaimo, British Columbia, V9R 3G9, Canada
Unknown Facility
New Westminster, British Columbia, V3L 3W4, Canada
Unknown Facility
Surrey, British Columbia, V3V 1Z2, Canada
Unknown Facility
Vancouver, British Columbia, V5Z 1M9, Canada
Unknown Facility
Vancouver, British Columbia, V6Z 1Y6, Canada
Unknown Facility
Victoria, British Columbia, V8R 4R2, Canada
Unknown Facility
Winnipeg, Manitoba, R2H 2A6, Canada
Unknown Facility
Winnipeg, Manitoba, R8A 1R9, Canada
Unknown Facility
Moncton, New Brunswick, E1G 1A7, Canada
Unknown Facility
Mount Pearl, Newfoundland and Labrador, A1N 1W7, Canada
Unknown Facility
St. John's, Newfoundland and Labrador, A1B 3V6, Canada
Unknown Facility
St. John's, Newfoundland and Labrador, A1E 2C2, Canada
Unknown Facility
St. John's, Newfoundland and Labrador, A1E 2E2, Canada
Unknown Facility
Halifax, Nova Scotia, B3H 3A7, Canada
Unknown Facility
Ajax, Ontario, L1S 7K8, Canada
Unknown Facility
Brampton, Ontario, L6Z 4N5, Canada
Unknown Facility
Burlington, Ontario, L7M 4Y1, Canada
Unknown Facility
Cambridge, Ontario, N1R 6V6, Canada
Unknown Facility
Cambridge, Ontario, N1R 7R1, Canada
Unknown Facility
Greater Sudbury, Ontario, P3E 2N8, Canada
Unknown Facility
Greater Sudbury, Ontario, P3E 3B8, Canada
Unknown Facility
Hamilton, Ontario, L8L 2X2, Canada
Unknown Facility
Kingston, Ontario, K7L 5G2, Canada
Unknown Facility
Kitchener, Ontario, N2H5Z8, Canada
Unknown Facility
Kitchener, Ontario, N2M 5N4, Canada
Unknown Facility
Mississauga, Ontario, L5B 2P7, Canada
Unknown Facility
Newmarket, Ontario, L3Y 8C3, Canada
Unknown Facility
Oshawa, Ontario, L1J 2J9, Canada
Unknown Facility
Ottawa, Ontario, K1Y 4W7, Canada
Unknown Facility
Thunder Bay, Ontario, P7B 2Z3, Canada
Unknown Facility
Thunder Bay, Ontario, P7B 6V4, Canada
Unknown Facility
Toronto, Ontario, M4N 3M5, Canada
Unknown Facility
Toronto, Ontario, M5B 1W8, Canada
Unknown Facility
Toronto, Ontario, M5G 1L7, Canada
Unknown Facility
Toronto, Ontario, M9W 4L6, Canada
Unknown Facility
Gatineau, Quebec, J8Y 6S9, Canada
Unknown Facility
Granby, Quebec, J2G 8Z9, Canada
Unknown Facility
Greenfield Park, Quebec, J4V 2G8, Canada
Unknown Facility
Lachine, Quebec, H8S 2E4, Canada
Unknown Facility
Laval, Quebec, H7M 3L9, Canada
Unknown Facility
Longueuil, Quebec, J4M 2X1, Canada
Unknown Facility
Montreal, Quebec, H1T 1C8, Canada
Unknown Facility
Montreal, Quebec, H1T 2M4, Canada
Unknown Facility
Montreal, Quebec, H2K 4L5, Canada
Unknown Facility
Montreal, Quebec, H2W 1T8, Canada
Unknown Facility
Montreal, Quebec, H3A 1A1, Canada
Unknown Facility
Montreal, Quebec, H3G 1A4, Canada
Unknown Facility
Montreal, Quebec, H4J 1C5, Canada
Unknown Facility
Québec, Quebec, G1J 1Z4, Canada
Unknown Facility
Québec, Quebec, G1R 2J6, Canada
Unknown Facility
Québec, Quebec, G1V 4M6, Canada
Unknown Facility
Saint Georges-de-beauce, Quebec, G5Y 4T8, Canada
Unknown Facility
Saint-Charles-Borromée, Quebec, J6E 6J2, Canada
Unknown Facility
Saint-Jérôme, Quebec, J7Z 5T3, Canada
Unknown Facility
Saint-Lambert, Quebec, J4P 2H4, Canada
Unknown Facility
Saint-Léonard, Quebec, H1S 3A9, Canada
Unknown Facility
Sherbrooke, Quebec, J1H 4J6, Canada
Unknown Facility
Sherbrooke, Quebec, J1H 5N4, Canada
Unknown Facility
Sherbrooke, Quebec, J1J 2E3, Canada
Unknown Facility
Ste. Foy, Quebec, G1V 4G5, Canada
Unknown Facility
Terrebonne, Quebec, J6V 2H2, Canada
Unknown Facility
Trois-Rivières, Quebec, G8T 7A1, Canada
Unknown Facility
Trois-Rivières, Quebec, G8Z 4K4, Canada
Unknown Facility
Val-d'Or, Quebec, J9P 3Y1, Canada
Unknown Facility
Westmount, Quebec, H3Z 2M6, Canada
Unknown Facility
Saskatoon, Saskatchewan, S7K 0H6, Canada
Unknown Facility
Beijing, 100020, China
Unknown Facility
Beijing, 100034, China
Unknown Facility
Beijing, 100037, China
Unknown Facility
Beijing, 100044, China
Unknown Facility
Beijing, 100088, China
Unknown Facility
Beijing, 100101, China
Unknown Facility
Beijing, 10029, China
Unknown Facility
Changsha, 410013, China
Unknown Facility
Dalian, 116027, China
Unknown Facility
Daqing, 163001, China
Unknown Facility
Guangzhou, 510120, China
Unknown Facility
Guangzhou, China
Unknown Facility
Hangzhou, 310003, China
Unknown Facility
Hangzhou, 310009, China
Unknown Facility
Hangzhou, 310016, China
Unknown Facility
Harbin, 150086, China
Unknown Facility
Jinan, 250033, China
Unknown Facility
Lanzhou, 730000, China
Unknown Facility
Lanzhou, 730030, China
Unknown Facility
Nanchang, 330006, China
Unknown Facility
Nanjing, 210029, China
Unknown Facility
Nanjing, 210036, China
Unknown Facility
Shanghai, 200003, China
Unknown Facility
Shanghai, 200032, China
Unknown Facility
Shanghai, 200065, China
Unknown Facility
Shanghai, 200233, China
Unknown Facility
Shenyang, 110004, China
Unknown Facility
Shenyang, 110016, China
Unknown Facility
Shijiazhuang, 05000, China
Unknown Facility
Shijiazhuang, 050082, China
Unknown Facility
Suzhou, 215004, China
Unknown Facility
Suzhou, 215006, China
Unknown Facility
Wenzhou, 325000, China
Unknown Facility
Wuhan, 430060, China
Unknown Facility
Wuhan, 430071, China
Unknown Facility
Xi'an, 710061, China
Unknown Facility
Brno, 656 91, Czechia
Unknown Facility
Chrudim, 537 25, Czechia
Unknown Facility
České Budějovice, 370 87, Czechia
Unknown Facility
Hradec Králové, 500 05, Czechia
Unknown Facility
Jihlava, 586 01, Czechia
Unknown Facility
Jindřichův Hradec, 377 38, Czechia
Unknown Facility
Karlovy Vary, 36066, Czechia
Unknown Facility
Kroměříž, 761 01, Czechia
Unknown Facility
Náchod, 547 01, Czechia
Unknown Facility
Ostrava - Fifejdy, 72880, Czechia
Unknown Facility
Pardubice, 53002, Czechia
Unknown Facility
Prague, 100 34, Czechia
Unknown Facility
Prague, 128 08, Czechia
Unknown Facility
Prague, 140 21, Czechia
Unknown Facility
Prague, 150 30, Czechia
Unknown Facility
Prague, 169 02, Czechia
Unknown Facility
Semily, 513 31, Czechia
Unknown Facility
Slaný, 274 01, Czechia
Unknown Facility
Tábor, 390 03, Czechia
Unknown Facility
Teplice, 415 01, Czechia
Unknown Facility
Trutnov, 541 01, Czechia
Unknown Facility
Zlín, 762 75, Czechia
Unknown Facility
Znojmo, 669 02, Czechia
Unknown Facility
Frederiksberg, 2000, Denmark
Unknown Facility
Hellerup, 2900, Denmark
Unknown Facility
Herlev, 2730, Denmark
Unknown Facility
Herning, 7400, Denmark
Unknown Facility
Hillerød, 3400, Denmark
Unknown Facility
Kolding, 6000, Denmark
Unknown Facility
København S, 2300, Denmark
Unknown Facility
Køge, 4600, Denmark
Unknown Facility
Roskilde, 4000, Denmark
Unknown Facility
Svendborg, 5700, Denmark
Unknown Facility
Jyväskylä, 40620, Finland
Unknown Facility
Kotka, 48100, Finland
Unknown Facility
Kuopio, 70211, Finland
Unknown Facility
Angers, 49033, France
Unknown Facility
Bron, 69677, France
Unknown Facility
Colmar, 68003, France
Unknown Facility
Dijon, 21034, France
Unknown Facility
Lille, 59037, France
Unknown Facility
Marseille, 13285, France
Unknown Facility
Marseille, 13385, France
Unknown Facility
Montfermeil, 93370, France
Unknown Facility
Paris, 75475, France
Unknown Facility
Paris, 75571, France
Unknown Facility
Paris, 75674, France
Unknown Facility
Paris, 75877, France
Unknown Facility
Paris, 75908, France
Unknown Facility
Pessac, 33604, France
Unknown Facility
Poitiers, 86021, France
Unknown Facility
Roubaix, 59056, France
Unknown Facility
Saint-Herblain, 44800, France
Unknown Facility
Strasbourg, 67010, France
Unknown Facility
Strasbourg, 67091, France
Unknown Facility
Tourcoing, 59208, France
Unknown Facility
Valenciennes, 59322, France
Unknown Facility
Vandœuvre-lès-Nancy, 54511, France
Unknown Facility
Bad Krozingen, 79189, Germany
Unknown Facility
Bad Rothenfelde, 49124, Germany
Unknown Facility
Bad Segeberg, 23795, Germany
Unknown Facility
Berlin, 10115, Germany
Unknown Facility
Berlin, 10117, Germany
Unknown Facility
Berlin, 10249, Germany
Unknown Facility
Berlin, 12157, Germany
Unknown Facility
Berlin, 12559, Germany
Unknown Facility
Berlin, 13353, Germany
Unknown Facility
Berlin, 14050, Germany
Unknown Facility
Bielefeld, 33604, Germany
Unknown Facility
Bochum, 44787, Germany
Unknown Facility
Bochum, 44789, Germany
Unknown Facility
Burg, 03096, Germany
Unknown Facility
Coburg, 96450, Germany
Unknown Facility
Darmstadt, 64283, Germany
Unknown Facility
Dortmund, 44137, Germany
Unknown Facility
Duisburg, 47137, Germany
Unknown Facility
Essen, 45122, Germany
Unknown Facility
Frankfurt, 65929, Germany
Unknown Facility
Frankfurt am Main, 60594, Germany
Unknown Facility
Führt, 90766, Germany
Unknown Facility
Halle, 06120, Germany
Unknown Facility
Hamburg, 20099, Germany
Unknown Facility
Heidelberg, 69120, Germany
Unknown Facility
Homburg/Saar, 66421, Germany
Unknown Facility
Langen, 63225, Germany
Unknown Facility
Limburg, 65552, Germany
Unknown Facility
Mainz, 55131, Germany
Unknown Facility
Mannheim, 68167, Germany
Unknown Facility
Mönchengladbach, 41063, Germany
Unknown Facility
Neuss, 41464, Germany
Unknown Facility
Northeim, 37154, Germany
Unknown Facility
Rüdersdorf, 15562, Germany
Unknown Facility
Ulm, 89081, Germany
Unknown Facility
Villingen-Schwenningen, 78048, Germany
Unknown Facility
Witten, 58455, Germany
Unknown Facility
Wuppertal, 42117, Germany
Unknown Facility
Toulouse, 31059, Grenada
Unknown Facility
Baja, 6500, Hungary
Unknown Facility
Békéscsaba, 5600, Hungary
Unknown Facility
Budapest, 1032, Hungary
Unknown Facility
Budapest, 1096, Hungary
Unknown Facility
Budapest, 1106, Hungary
Unknown Facility
Budapest, 1115, Hungary
Unknown Facility
Budapest, 1125, Hungary
Unknown Facility
Budapest, 1135, Hungary
Unknown Facility
Budapest, H - 1041, Hungary
Unknown Facility
Debrecen, 4032, Hungary
Unknown Facility
Kalocsa, 6300, Hungary
Unknown Facility
Kecskemét, 6000, Hungary
Unknown Facility
Pécs, 7624, Hungary
Unknown Facility
Sopron, 9400, Hungary
Unknown Facility
Szeged, 6720, Hungary
Unknown Facility
Szekszárd, 7100, Hungary
Unknown Facility
Székesfehérvár, 8000, Hungary
Unknown Facility
Zalaegerszeg, 8900, Hungary
Unknown Facility
Dublin, 7, Ireland
Unknown Facility
Dublin, 8, Ireland
Unknown Facility
Dublin, 9, Ireland
Unknown Facility
Afula, 18101, Israel
Unknown Facility
Beersheba, 84101, Israel
Unknown Facility
Giv‘atayim, 53583, Israel
Unknown Facility
Hadera, 38100, Israel
Unknown Facility
Haifa, 31048, Israel
Unknown Facility
Haifa, 3109601, Israel
Unknown Facility
Haifa, 31096, Israel
Unknown Facility
Haifa, 34362, Israel
Unknown Facility
Jerusalem, 91031, Israel
Unknown Facility
Jerusalem, 91120, Israel
Unknown Facility
Jerusalem, 91240, Israel
Unknown Facility
Kfar Saba, 44281, Israel
Unknown Facility
Nahariya, 22100, Israel
Unknown Facility
Nazareth, 16100, Israel
Unknown Facility
Petah Tikva, 49100, Israel
Unknown Facility
Petah Tikva, 4941492, Israel
Unknown Facility
Rehovot, 76100, Israel
Unknown Facility
Tel Aviv, 6423906, Israel
Unknown Facility
Tel Aviv, 64239, Israel
Unknown Facility
Tel Litwinsky, 52661, Israel
Unknown Facility
Tiberias, 15208, Israel
Unknown Facility
Ẕerifin, 70300, Israel
Unknown Facility
Chieti, Abruzzo, 66100, Italy
Unknown Facility
Caserta, Campania, 81100, Italy
Unknown Facility
Napoli, Campania, 80131, Italy
Unknown Facility
Carpi, Emilia-Romagna, 41012, Italy
Unknown Facility
Forlì, Emilia-Romagna, 47100, Italy
Unknown Facility
Modena, Emilia-Romagna, 41100, Italy
Unknown Facility
Piacenza, Emilia-Romagna, 29100, Italy
Unknown Facility
Udine, Friuli Venezia Giulia, 33100, Italy
Unknown Facility
Rome, Lazio, 00152, Italy
Unknown Facility
Rome, Lazio, 00184, Italy
Unknown Facility
Genoa, Liguria, 16128, Italy
Unknown Facility
Bergamo, Lombardy, 24128, Italy
Unknown Facility
Como, Lombardy, 22020, Italy
Unknown Facility
Milan, Lombardy, 20138, Italy
Unknown Facility
Pavia, Lombardy, 27100, Italy
Unknown Facility
Rozzano, Lombardy, 20089, Italy
Unknown Facility
Novara, Piedmont, 28100, Italy
Unknown Facility
Turin, Piedmont, 10126, Italy
Unknown Facility
Pesaro, The Marches, 61100, Italy
Unknown Facility
Castelnuovo, Tuscany, 55032, Italy
Unknown Facility
S. Bonifacio, Veneto, 37047, Italy
Unknown Facility
Treviso, Veneto, 31100, Italy
Unknown Facility
's-Hertogenbosch, 5223 GZ, Netherlands
Unknown Facility
Alkmaar, 1815 JD, Netherlands
Unknown Facility
Almelo, 7609 PP, Netherlands
Unknown Facility
Amersfoort, 3818 ES, Netherlands
Unknown Facility
Amstelveen, 1186 AH, Netherlands
Unknown Facility
Amsterdam, 1061 AE, Netherlands
Unknown Facility
Amsterdam, 1066 EC, Netherlands
Unknown Facility
Amsterdam, 1081 HV, Netherlands
Unknown Facility
Amsterdam, 1091 AC, Netherlands
Unknown Facility
Amsterdam, 1105 AZ, Netherlands
Unknown Facility
Arnhem, 6815 AD, Netherlands
Unknown Facility
Blaricum, 1261 AN, Netherlands
Unknown Facility
Breda, 4818 CK, Netherlands
Unknown Facility
Capelle AD Yssel, 2906 ZC, Netherlands
Unknown Facility
Delft, 2625 AD, Netherlands
Unknown Facility
Den Helder, 1782GZ, Netherlands
Unknown Facility
Deventer, 7415 CM, Netherlands
Unknown Facility
Eindhoven, 5623 EJ, Netherlands
Unknown Facility
Enschede, 7512 KZ, Netherlands
Unknown Facility
Goes, 4462 RA, Netherlands
Unknown Facility
Groningen, 9728 NZ, Netherlands
Unknown Facility
Haarlem, 2035 RC, Netherlands
Unknown Facility
Heerlen, 6419 PC, Netherlands
Unknown Facility
Hengelo, 7555 DL, Netherlands
Unknown Facility
Hilversum, 1213 HX, Netherlands
Unknown Facility
Hoofddorp, 2134 TM, Netherlands
Unknown Facility
Hoorn, 1625 HV, Netherlands
Unknown Facility
Leiden, 2300 RC, Netherlands
Unknown Facility
Leiderdorp, 2353 GA, Netherlands
Unknown Facility
Maastricht, 6202 AZ, Netherlands
Unknown Facility
Nieuwegein, 3430 EM, Netherlands
Unknown Facility
Nijmegen, 6532 SZ, Netherlands
Unknown Facility
Purmerend, 1441 RN, Netherlands
Unknown Facility
Rotterdam, 3045 PM, Netherlands
Unknown Facility
Rotterdam, 3075 EA, Netherlands
Unknown Facility
Rotterdam, 3083 AN, Netherlands
Unknown Facility
Sneek, 8601 ZK, Netherlands
Unknown Facility
Stadskanaal, 9501 HE, Netherlands
Unknown Facility
Tilburg, 5022 GC, Netherlands
Unknown Facility
Tilburg, 5042 AD, Netherlands
Unknown Facility
Utrecht, 3584 CX, Netherlands
Unknown Facility
Weert, 6001 BE, Netherlands
Unknown Facility
Zaandam, 1502 DV, Netherlands
Unknown Facility
Zwolle, 8011 JW, Netherlands
Unknown Facility
Auckland, 1023, New Zealand
Unknown Facility
Auckland, New Zealand
Unknown Facility
Christchurch, 8011, New Zealand
Unknown Facility
Dunedin, New Zealand
Unknown Facility
Hamilton, 3240, New Zealand
Unknown Facility
Nelson, 7001, New Zealand
Unknown Facility
New Plymouth, 4620, New Zealand
Unknown Facility
Wellington, 6012, New Zealand
Unknown Facility
Bialystok, 15-276, Poland
Unknown Facility
Bydgoszcz, 85-435, Poland
Unknown Facility
Bydgoszcz, 85-826, Poland
Unknown Facility
Elblag, 82-300, Poland
Unknown Facility
Gdansk, 80-211, Poland
Unknown Facility
Gdynia, 81-402, Poland
Unknown Facility
Gdynia, 81-472, Poland
Unknown Facility
Grodzisk Mazowiecki, 05-825, Poland
Unknown Facility
Inowrocław, 88-100, Poland
Unknown Facility
Katowice, 40-635, Poland
Unknown Facility
Krakow, 30-069, Poland
Unknown Facility
Krakow, 31-202, Poland
Unknown Facility
Lodz, 91-425, Poland
Unknown Facility
Lodz, 93-113, Poland
Unknown Facility
Lublin, 20-089, Poland
Unknown Facility
Nowa Sól, 67-100, Poland
Unknown Facility
Poznan, 61-833, Poland
Unknown Facility
Poznan, 61-848, Poland
Unknown Facility
Puławy, 24-100, Poland
Unknown Facility
Płock, 09-400, Poland
Unknown Facility
Ruda Śląska, 41-703, Poland
Unknown Facility
Siedlce, 08-110, Poland
Unknown Facility
Sopot, 81-717, Poland
Unknown Facility
Sosnowiec, 41-200, Poland
Unknown Facility
Stalowa Wola, 37-450, Poland
Unknown Facility
Starachowice, 27-200, Poland
Unknown Facility
Szczecin, 70-111, Poland
Unknown Facility
Świdnik, 21-040, Poland
Unknown Facility
Tarnów, 33-100, Poland
Unknown Facility
Torun, 87-100, Poland
Unknown Facility
Warsaw, 00-217, Poland
Unknown Facility
Warsaw, 02-507, Poland
Unknown Facility
Warsaw, 02-637, Poland
Unknown Facility
Warsaw, 03-242, Poland
Unknown Facility
Warsaw, 96-100, Poland
Unknown Facility
Wałbrzych, 58-309, Poland
Unknown Facility
Wroclaw, 50-159, Poland
Unknown Facility
Wroclaw, 50-420, Poland
Unknown Facility
Wroclaw, 50-981, Poland
Unknown Facility
Zamość, 22-400, Poland
Unknown Facility
Zielona Góra, 65-046, Poland
Unknown Facility
Aguas Buenas, 00703, Puerto Rico
Unknown Facility
Caguas, 00725, Puerto Rico
Unknown Facility
Manatí, 00674, Puerto Rico
Unknown Facility
Ponce, 00716, Puerto Rico
Unknown Facility
Ponce, 00717, Puerto Rico
Unknown Facility
Río Grande, 00745, Puerto Rico
Unknown Facility
San Juan, 00921, Puerto Rico
Unknown Facility
Toa Baja, 00949, Puerto Rico
Unknown Facility
Banská Bystrica, 974 01, Slovakia
Unknown Facility
Bardejov, 08501, Slovakia
Unknown Facility
Bratislava, 813 69, Slovakia
Unknown Facility
Bratislava, 826 06, Slovakia
Unknown Facility
Dolný Kubín, 02601, Slovakia
Unknown Facility
Martin, 036 59, Slovakia
Unknown Facility
Nitra, 949 01, Slovakia
Unknown Facility
Rimavská Sobota, 979 01, Slovakia
Unknown Facility
Žilina, 012 07, Slovakia
Unknown Facility
Alberton, 1449, South Africa
Unknown Facility
Bloemfontein, 9301, South Africa
Unknown Facility
Boksburg, 1459, South Africa
Unknown Facility
Durban, 4001, South Africa
Unknown Facility
Durban, 4091, South Africa
Unknown Facility
Johannesburg, 2000, South Africa
Unknown Facility
Johannesburg, 2013, South Africa
Unknown Facility
Johannesburg, 2157, South Africa
Unknown Facility
Kuilsriver, 7580, South Africa
Unknown Facility
Lyttelton, Pretoria, 0157, South Africa
Unknown Facility
Panorama, 7500, South Africa
Unknown Facility
Pinelands, 7405, South Africa
Unknown Facility
Pretoria, 0040, South Africa
Unknown Facility
Somerset West, 7130, South Africa
Unknown Facility
Busan, 602-715, South Korea
Unknown Facility
Daegu, 700-712, South Korea
Unknown Facility
Daegu, 705-717, South Korea
Unknown Facility
Gangwon-Do, 200-704, South Korea
Unknown Facility
Gangwon-do, 24289, South Korea
Unknown Facility
Gwangju, 61469, South Korea
Unknown Facility
Gyeonggi-do, 10380, South Korea
Unknown Facility
Gyeonggi-do, 10475, South Korea
Unknown Facility
Incheon, 405-760, South Korea
Unknown Facility
Kyonggi-do, 411-719, South Korea
Unknown Facility
Seoul, 05505, South Korea
Unknown Facility
Seoul, 120-752, South Korea
Unknown Facility
Seoul, 134-791, South Korea
Unknown Facility
Seoul, 140-73, South Korea
Unknown Facility
Seoul, 156-707, South Korea
Unknown Facility
Vitoria-Gasteiz, Alava, 01006, Spain
Unknown Facility
Sant Joan d'Alacant, Alicante, 3550, Spain
Unknown Facility
L'Hospitalet de Llobregat, Barcelona, 08907, Spain
Unknown Facility
Santander, Cantabria, 39008, Spain
Unknown Facility
Figueres, Girona, 17600, Spain
Unknown Facility
Santiago de Compostela, LA Coruña, 15706, Spain
Unknown Facility
Majadahonda, Madrid, 28222, Spain
Unknown Facility
Málaga, Malaga, 29010, Spain
Unknown Facility
Pamplona, Navarre, 31008, Spain
Unknown Facility
Vigo, Pontevedra, 36214, Spain
Unknown Facility
Seville, Sevilla, 41071, Spain
Unknown Facility
Alicante, 03010, Spain
Unknown Facility
Almería, 04009, Spain
Unknown Facility
Barcelona, 08003, Spain
Unknown Facility
Guadalajara, 19002, Spain
Unknown Facility
Lugo, 27004, Spain
Unknown Facility
Madrid, 28006, Spain
Unknown Facility
Madrid, 28040, Spain
Unknown Facility
Madrid, 28046, Spain
Unknown Facility
Tarragona, 43007, Spain
Unknown Facility
Valencia, 46014, Spain
Unknown Facility
Valladolid, 47005, Spain
Unknown Facility
Falun, 79182, Sweden
Unknown Facility
Gothenburg, 416 85, Sweden
Unknown Facility
Stockholm, 11883, Sweden
Unknown Facility
Stockholm, 18288, Sweden
Unknown Facility
Västerås, 72189, Sweden
Unknown Facility
Fribourg, 1708, Switzerland
Unknown Facility
Geneva, 1211, Switzerland
Unknown Facility
Kreuzlingen, 8280, Switzerland
Unknown Facility
Lucerne, 6000, Switzerland
Unknown Facility
Lugano, 6900, Switzerland
Unknown Facility
Münsterlingen, 8596, Switzerland
Unknown Facility
Wolhusen, 6110, Switzerland
Unknown Facility
Airdrie, ML6 0JS, United Kingdom
Unknown Facility
Barnet, EN5 3DJ, United Kingdom
Unknown Facility
Belfast, BT47 6SB, United Kingdom
Unknown Facility
Birmingham, B18 7QH, United Kingdom
Unknown Facility
Birmingham, B75 7RR, United Kingdom
Unknown Facility
Blackpool, FY3 8NR, United Kingdom
Unknown Facility
Bradford, BD9 6RJ, United Kingdom
Unknown Facility
Cambridge, CB1 8RN, United Kingdom
Unknown Facility
Chertsey, KT16 0PZ, United Kingdom
Unknown Facility
Edinburgh, EH16 4SB, United Kingdom
Unknown Facility
Glasgow, G11 6NK, United Kingdom
Unknown Facility
Glasgow, G31 2ER, United Kingdom
Unknown Facility
Glasgow, G51 4TF, United Kingdom
Unknown Facility
Larbert, FK5 4WR, United Kingdom
Unknown Facility
Leicester, LE3 9QP, United Kingdom
Unknown Facility
London, E11 1NR, United Kingdom
Unknown Facility
London, EC1M 6BQ, United Kingdom
Unknown Facility
Luton, LU4 0DZ, United Kingdom
Unknown Facility
Manchester, M13 9WL, United Kingdom
Unknown Facility
Middlesbrough, TS4 3BW, United Kingdom
Unknown Facility
Middlesex, UB1 3HW, United Kingdom
Unknown Facility
Nottingham, NG5 1PB, United Kingdom
Unknown Facility
Nuneaton, CV10 7DJ, United Kingdom
Unknown Facility
Paisley, PA2 9PN, United Kingdom
Unknown Facility
Peterborough, PE3 6DA, United Kingdom
Unknown Facility
Stockport, SK2 7JE, United Kingdom
Unknown Facility
Swansea, SA6 6NL, United Kingdom
Related Publications (12)
Schwartz GG, Leiter LA, Ballantyne CM, Barter PJ, Black DM, Kallend D, Laghrissi-Thode F, Leitersdorf E, McMurray JJV, Nicholls SJ, Olsson AG, Preiss D, Shah PK, Tardif JC, Kittelson J. Dalcetrapib Reduces Risk of New-Onset Diabetes in Patients With Coronary Heart Disease. Diabetes Care. 2020 May;43(5):1077-1084. doi: 10.2337/dc19-2204. Epub 2020 Mar 6.
PMID: 32144166DERIVEDSalahuddin T, Kittelson J, Tardif JC, Shah PK, Olsson AG, Nicholls SJ, Leitersdorf E, Leiter LA, Kallend D, Black DM, Barter PJ, Ballantyne CM, Schwartz GG. Association of high-density lipoprotein particle concentration with cardiovascular risk following acute coronary syndrome: A case-cohort analysis of the dal-Outcomes trial. Am Heart J. 2020 Mar;221:60-66. doi: 10.1016/j.ahj.2019.12.003. Epub 2019 Dec 16.
PMID: 31927126DERIVEDSchwartz GG, Ballantyne CM, Barter PJ, Kallend D, Leiter LA, Leitersdorf E, McMurray JJV, Nicholls SJ, Olsson AG, Shah PK, Tardif JC, Kittelson J. Association of Lipoprotein(a) With Risk of Recurrent Ischemic Events Following Acute Coronary Syndrome: Analysis of the dal-Outcomes Randomized Clinical Trial. JAMA Cardiol. 2018 Feb 1;3(2):164-168. doi: 10.1001/jamacardio.2017.3833.
PMID: 29071331DERIVEDPitts R, Gunzburger E, Ballantyne CM, Barter PJ, Kallend D, Leiter LA, Leitersdorf E, Nicholls SJ, Shah PK, Tardif JC, Olsson AG, McMurray JJ, Kittelson J, Schwartz GG. Aldosterone Does Not Predict Cardiovascular Events Following Acute Coronary Syndrome in Patients Initially Without Heart Failure. J Am Heart Assoc. 2017 Jan 10;6(1):e004119. doi: 10.1161/JAHA.116.004119.
PMID: 28073769DERIVEDTardif JC, Rhainds D, Brodeur M, Feroz Zada Y, Fouodjio R, Provost S, Boule M, Alem S, Gregoire JC, L'Allier PL, Ibrahim R, Guertin MC, Mongrain I, Olsson AG, Schwartz GG, Rheaume E, Dube MP. Genotype-Dependent Effects of Dalcetrapib on Cholesterol Efflux and Inflammation: Concordance With Clinical Outcomes. Circ Cardiovasc Genet. 2016 Aug;9(4):340-8. doi: 10.1161/CIRCGENETICS.116.001405. Epub 2016 Jul 14.
PMID: 27418594DERIVEDSchwartz GG, Abt M, Bao W, DeMicco D, Kallend D, Miller M, Mundl H, Olsson AG. Fasting triglycerides predict recurrent ischemic events in patients with acute coronary syndrome treated with statins. J Am Coll Cardiol. 2015 Jun 2;65(21):2267-75. doi: 10.1016/j.jacc.2015.03.544.
PMID: 26022813DERIVEDTardif JC, Rheaume E, Lemieux Perreault LP, Gregoire JC, Feroz Zada Y, Asselin G, Provost S, Barhdadi A, Rhainds D, L'Allier PL, Ibrahim R, Upmanyu R, Niesor EJ, Benghozi R, Suchankova G, Laghrissi-Thode F, Guertin MC, Olsson AG, Mongrain I, Schwartz GG, Dube MP. Pharmacogenomic determinants of the cardiovascular effects of dalcetrapib. Circ Cardiovasc Genet. 2015 Apr;8(2):372-82. doi: 10.1161/CIRCGENETICS.114.000663. Epub 2015 Jan 11.
PMID: 25583994DERIVEDSchwartz GG, Olsson AG, Abt M, Ballantyne CM, Barter PJ, Brumm J, Chaitman BR, Holme IM, Kallend D, Leiter LA, Leitersdorf E, McMurray JJ, Mundl H, Nicholls SJ, Shah PK, Tardif JC, Wright RS; dal-OUTCOMES Investigators. Effects of dalcetrapib in patients with a recent acute coronary syndrome. N Engl J Med. 2012 Nov 29;367(22):2089-99. doi: 10.1056/NEJMoa1206797. Epub 2012 Nov 5.
PMID: 23126252DERIVEDLuscher TF, Taddei S, Kaski JC, Jukema JW, Kallend D, Munzel T, Kastelein JJ, Deanfield JE; dal-VESSEL Investigators. Vascular effects and safety of dalcetrapib in patients with or at risk of coronary heart disease: the dal-VESSEL randomized clinical trial. Eur Heart J. 2012 Apr;33(7):857-65. doi: 10.1093/eurheartj/ehs019. Epub 2012 Feb 16.
PMID: 22345126DERIVEDDerks M, Abt M, Parr G, Meneses-Lorente G, Young AM, Phelan M. No clinically relevant drug-drug interactions when dalcetrapib is co-administered with atorvastatin. Expert Opin Investig Drugs. 2010 Oct;19(10):1135-45. doi: 10.1517/13543784.2010.509342.
PMID: 20738227DERIVEDSchwartz GG, Olsson AG, Ballantyne CM, Barter PJ, Holme IM, Kallend D, Leiter LA, Leitersdorf E, McMurray JJ, Shah PK, Tardif JC, Chaitman BR, Duttlinger-Maddux R, Mathieson J; dal-OUTCOMES Committees and Investigators. Rationale and design of the dal-OUTCOMES trial: efficacy and safety of dalcetrapib in patients with recent acute coronary syndrome. Am Heart J. 2009 Dec;158(6):896-901.e3. doi: 10.1016/j.ahj.2009.09.017.
PMID: 19958854DERIVEDStein EA, Stroes ES, Steiner G, Buckley BM, Capponi AM, Burgess T, Niesor EJ, Kallend D, Kastelein JJ. Safety and tolerability of dalcetrapib. Am J Cardiol. 2009 Jul 1;104(1):82-91. doi: 10.1016/j.amjcard.2009.02.061.
PMID: 19576325DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Results Point of Contact
- Title
- Ryan Black
- Organization
- DalCor Pharmaceuticals
Study Officials
- STUDY DIRECTOR
Clinical Trials
Hoffmann-La Roche
Publication Agreements
- PI is Sponsor Employee
- No
- Restrictive Agreement
- No
Study Design
- Study Type
- interventional
- Phase
- phase 3
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, INVESTIGATOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- INDUSTRY
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
March 28, 2008
First Posted
April 15, 2008
Study Start
April 1, 2008
Primary Completion
September 1, 2012
Study Completion
September 1, 2012
Last Updated
January 3, 2020
Results First Posted
January 3, 2020
Record last verified: 2019-12