Cognitive Training in Attenuating Attention Deficits/Child Treatment for Cancer
A Pilot Study of the Effectiveness of Cognitive Training in Preventing Attention Deficits Among Children in Treatment for Cancer
1 other identifier
observational
30
1 country
1
Brief Summary
Primary Objectives:
- 1.To evaluate the feasibility of enrolling children and adolescents with newly diagnosed brain tumors, leukemia, or lymphoma in a program designed to prevent the academic and cognitive declines that commonly result following central nervous system (CNS) disease and treatment.
- 2.To evaluate whether a Cognitive Training Program (CTP) might be helpful to patients in preventing attention deficits that commonly result following CNS disease and therapy.
- 3.To explore the relationship between CTP treatment compliance and stability/decline in cognitive and academic performance in children and adolescents who are being treated for brain tumors, leukemia, and lymphoma.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Apr 2004
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 1, 2004
CompletedFirst Submitted
Initial submission to the registry
July 9, 2007
CompletedFirst Posted
Study publicly available on registry
July 10, 2007
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 1, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
September 1, 2025
CompletedDecember 31, 2020
December 1, 2020
20.4 years
July 9, 2007
December 29, 2020
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Number of Participants with Academic + Cognitive Decline Pre- to Post-Treatment
Determine whether Cognitive Training Program (CTP) prevents declines in cognitive and academic skills by comparing change from pre- to post-treatment through Academic achievement tests and psychological adjustment questionnaires at three points of time (baseline, at the end of training and 6 months later)
5 Years
Study Arms (2)
CTP Group
One-on-one cognitive training
Control Group
Standard educational support.
Interventions
Cognitive training sessions over a 4 to 6 month training period, each lasting about 2 hours.
Eligibility Criteria
Participants with leukemia, lymphoma, or brain tumor that are at least 6 years old.
You may qualify if:
- Eligibility criteria to participate in the study are: at least 6-years-old.
- Enrolled in school or homebound instruction in a grade Kindergarten through 12th.
- A diagnosis of leukemia, lymphoma, or brain tumor (e.g., primary brain tumors, leptomeningeal infiltration, or metastases) that requires treatment of the CNS (surgery, CRT, and/or chemotherapy).
- Within 2 months to 14 months after beginning treatment for cancer.
- Full scale IQ \> or = 70.
- English-speaking. (This is defined as the ability to appropriately respond to test and training materials.)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Texas MD Anderson Cancer Center
Houston, Texas, 77030, United States
Related Links
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Martha Askins, PhD
M.D. Anderson Cancer Center
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
July 9, 2007
First Posted
July 10, 2007
Study Start
April 1, 2004
Primary Completion
September 1, 2024
Study Completion
September 1, 2025
Last Updated
December 31, 2020
Record last verified: 2020-12