Key Insights

Highlights

Success Rate

84% trial completion

Published Results

35 trials with published results (10%)

Research Maturity

150 completed trials (42% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

8.1%

29 terminated out of 356 trials

Success Rate

83.8%

-2.8% vs benchmark

Late-Stage Pipeline

8%

27 trials in Phase 3/4

Results Transparency

23%

35 of 150 completed with results

Key Signals

35 with results84% success29 terminated

Data Visualizations

Phase Distribution

251Total
Not Applicable (120)
Early P 1 (14)
P 1 (59)
P 2 (31)
P 3 (18)
P 4 (9)

Trial Status

Completed150
Recruiting75
Unknown40
Terminated29
Active Not Recruiting25
Withdrawn17

Trial Success Rate

83.8%

Benchmark: 86.6%

Based on 150 completed trials

Clinical Trials (356)

Showing 20 of 20 trials
NCT04085887Phase 1RecruitingPrimary

Panitumumab-IRDye800 to Detect Pediatric Neoplasms During Neurosurgical Procedures

NCT07224503Not ApplicableRecruitingPrimary

C-SMART vs BE Well for Patients With Brain Tumors

NCT01944761Not ApplicableCompletedPrimary

The Neuro-protective Effects of Exercise in Children With Brain Tumors

NCT05733312Not ApplicableRecruitingPrimary

Extracellular Impact of Ultrasound-induced Blood-brain Barrier Disruption

NCT02153957Phase 2CompletedPrimary

Trial Evaluating an Enhanced Physical Activity Intervention to Improve Cognitive Late Effects in Children Treated With Cranial Radiation for Brain Tumors

NCT07470606Phase 2RecruitingPrimary

Memantine +/- Raloxifene for Cognitive Preservation After Radiation Therapy to the Brain

NCT07831772Not ApplicableRecruiting

REMIND Maintenance Radiotherapy for Newly Diagnosed Glioblastoma

NCT06630338Not Yet RecruitingPrimary

Use of Shear Wave Elastography for Intraoperative Brain and Tumor Stiffness Measurements

NCT06101069Not ApplicableRecruitingPrimary

Development of MRF for Characterization of Brain Tumors After Radiotherapy

NCT07105358Not ApplicableRecruiting

Vision Improvement Through Behavioral Rehabilitation And Neuroplasticity Training

NCT07635329Not ApplicableRecruiting

Home-based Vision Rehabilitation Guided by Brain Imaging

NCT07039760Early Phase 1Not Yet RecruitingPrimary

Asciminib With or Without Sildenafil for Brain Tumors

NCT04033497Not ApplicableRecruitingPrimary

Treatment Response Assessment Maps to Delineate Necrosis From Tumor After Stereotactic Radiation in Brain Metastases

NCT06329570Phase 1Suspended

Safety and Efficacy of Bevacizumab in Combination With NaviFUS System for the Treatment of Recurrent Glioblastoma Multiforme (rGBM)

NCT04899908Phase 2Recruiting

Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases

NCT07390539Phase 1Recruiting

B7-H3.CD28Z.CART in CNS Neoplasms

NCT07797660Not Yet Recruiting

A Study for Postoperative Delirium in Older Patients With Intracranial Tumors

NCT05588141Phase 1RecruitingPrimary

A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations

NCT04181684Not ApplicableActive Not Recruiting

LITT Followed by Hypofractionated RT for Recurrent Gliomas

NCT02851706Completed

Natural History of and Specimen Banking for People With Tumors of the Central Nervous System

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