Key Insights

Highlights

Success Rate

84% trial completion

Published Results

34 trials with published results (10%)

Research Maturity

149 completed trials (42% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

8.2%

29 terminated out of 353 trials

Success Rate

83.7%

-2.8% vs benchmark

Late-Stage Pipeline

8%

27 trials in Phase 3/4

Results Transparency

23%

34 of 149 completed with results

Key Signals

34 with results84% success29 terminated

Data Visualizations

Phase Distribution

249Total
Not Applicable (118)
Early P 1 (14)
P 1 (59)
P 2 (31)
P 3 (18)
P 4 (9)

Trial Status

Completed149
Recruiting73
Unknown40
Terminated29
Active Not Recruiting24
Withdrawn17

Trial Success Rate

83.7%

Benchmark: 86.5%

Based on 149 completed trials

Clinical Trials (353)

Showing 20 of 20 trials
NCT05047913Early Phase 1Active Not RecruitingPrimary

Comprehensive Evaluation of Tumor Oxygenation, Metabolism and Blood Supply of High Grade Glioma and Cervical Cancers Using Dynamic FAZA PET and Multiparametric MR

NCT05317858Phase 3RecruitingPrimary

Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets

NCT04427384Recruiting

Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)

NCT07710131Not ApplicableNot Yet Recruiting

Neurocognitive Assessment CNSL and LGG

NCT02153957Phase 2CompletedPrimary

Trial Evaluating an Enhanced Physical Activity Intervention to Improve Cognitive Late Effects in Children Treated With Cranial Radiation for Brain Tumors

NCT02851706Completed

Natural History of and Specimen Banking for People With Tumors of the Central Nervous System

NCT03972514Active Not RecruitingPrimary

Observational Trial of the Impact of Radiation Dose in Children With Brain and Skull Base Tumors.

NCT05989893Not ApplicableRecruiting

Mapping of Human Cognition

NCT03220646Phase 2Active Not RecruitingPrimary

Abemaciclib (LY2835219) in Patients With Recurrent Primary Brain Tumors

NCT07680439Phase 2Not Yet Recruiting

Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG).

NCT03208387Active Not RecruitingPrimary

Understanding the Late Effects of Surviving a Pediatric Brain Tumor

NCT07039760Early Phase 1Not Yet RecruitingPrimary

Asciminib With or Without Sildenafil for Brain Tumors

NCT06455189Phase 1Withdrawn

Magnetic Resonance Fingerprinting Guided Extended Resection in Glioblastomas

NCT06388733Phase 3Active Not Recruiting

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

NCT06368310Not ApplicableCompletedPrimary

FIH Clinical Investigation of Graphene Electrodes for Brain Mapping

NCT07675070RecruitingPrimary

Safety and Effectiveness Evaluation of Temozolomide (Amitzo, NanoAlvand) in Patients With Grade III and IV Glioma Tumors

NCT04085887Phase 1RecruitingPrimary

Panitumumab-IRDye800 to Detect Pediatric Neoplasms During Neurosurgical Procedures

NCT05658731Not ApplicableRecruitingPrimary

Cognitive Outcomes After Brain Substructure-informed Radiation Planning in Pediatric Patients

NCT05588141Phase 1RecruitingPrimary

A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations

NCT07003542Phase 2Recruiting

A Phase 2 and Pharmacodynamic Study of Sitagliptin in Patients With Progressive Grade 4 Gliomas

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