NCT00464035

Brief Summary

The purpose of this study is to investigate the effect of calcium on postprandial lipid profile and appetite.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
18

participants targeted

Target at below P25 for not_applicable obesity

Timeline
Completed

Started Feb 2005

Shorter than P25 for not_applicable obesity

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2005

Completed
8 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2005

Completed
1.5 years until next milestone

First Submitted

Initial submission to the registry

April 19, 2007

Completed
1 day until next milestone

First Posted

Study publicly available on registry

April 20, 2007

Completed
Last Updated

January 21, 2009

Status Verified

December 1, 2004

First QC Date

April 19, 2007

Last Update Submit

January 20, 2009

Conditions

Obesity

Keywords

ObesityCalciumFat absorptionPostprandial lipid profileappetite

Outcome Measures

Primary Outcomes (1)

  • Postprandial changes in: total plasma triacylglyceride; Chylomicron triacylglyceride; Cholesterol

Secondary Outcomes (1)

  • Postprandial changes in:insulin; glucose; CCK; Ghrelin; GLP-1, appetite measured by visual analogue scales, BCAA

Interventions

high calcium intakeBEHAVIORAL

Eligibility Criteria

Age18 Years - 50 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • healthy meals
  • BMI 24-31 kg/m2
  • age between 18-50 years
  • hemoglobin \>8 mmol/L

You may not qualify if:

  • donation of blood 6 months before and under the study
  • milk allergy, diabetes, hypertension, hyperlipidemia, cronic infectious disease
  • use of dietary supplements 3 months before and under the study
  • smoking
  • elite athletes
  • use of medication

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Institute of Human Nutrition

Copenhagen, 1958, Denmark

Location

MeSH Terms

Conditions

Obesity

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Arne Astrup, Prof. Dr.

    Institute of Human Nutrition, the Royal Veterinary & Agricultural University, Denmark

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Intervention Model
CROSSOVER
Sponsor Type
OTHER

Study Record Dates

First Submitted

April 19, 2007

First Posted

April 20, 2007

Study Start

February 1, 2005

Study Completion

October 1, 2005

Last Updated

January 21, 2009

Record last verified: 2004-12

Locations

DK(1)