NCT01199835

Brief Summary

The aim of the study is to investigate the long time effects of high and low intake of dairy products on fecal fat excretion, weight loss, blood pressure, lipid profile, lipid oxidation and appetite regulation in moderately overweight men and women over 24 weeks.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
80

participants targeted

Target at P50-P75 for not_applicable obesity

Timeline
Completed

Started Jun 2010

Typical duration for not_applicable obesity

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2010

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

September 8, 2010

Completed
5 days until next milestone

First Posted

Study publicly available on registry

September 13, 2010

Completed
2.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2012

Completed
Last Updated

June 11, 2014

Status Verified

June 1, 2014

Enrollment Period

2.3 years

First QC Date

September 8, 2010

Last Update Submit

June 10, 2014

Conditions

Keywords

obesitymetabolic syndromefecal fat excretionfecal calciumweight lossappetite regulationintestinal micro floralipid profileenergy balance

Outcome Measures

Primary Outcomes (3)

  • Fecal fat excretion

    24 weeks

  • Body weight

    24 weeks

  • body composition

    24 weeks

Secondary Outcomes (11)

  • Resting energy expenditure

    24 weeks

  • Blood pressure

    24 weeks

  • Appetite regulation

    24 weeks

  • Lipid profile

    24 weeks

  • Intestinal micro flora

    24 weeks

  • +6 more secondary outcomes

Study Arms (2)

high calcium

EXPERIMENTAL

Dietary intake of calcium \~ 1500 mg/ d, including \~1200 mg/d from dairy products

Other: High Calcium intake from dairy products

Low calcium

ACTIVE COMPARATOR

Low dietary intake of calcium, i.e. \~ \<600 mg/d, including 0-1 portion of dairy products

Other: High Calcium intake from dairy products

Interventions

High dietary intake of calcium from dairy products (\~1200 mg/d)

Low calciumhigh calcium

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • men and women,
  • medium overweight (body mass index 28-36 kg/m2),
  • years old,
  • low habitual calcium intake (\<800 mg/d)

You may not qualify if:

  • milk allergy, infection diseases and diabetes,
  • intake of dietary supplements,
  • smoking,
  • pregnancy and/or breast feeding,
  • any medications known to affect the outcome measurements,
  • weigh reducing diet,
  • gastrointestinal diseases,
  • participation in other intervention studies

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Exercise, Nutrition and Sports, Faculty of Sciences, University of Copenhagen

Frederiksberg, 1958, Denmark

Location

MeSH Terms

Conditions

ObesityMetabolic SyndromeWeight Loss

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and SymptomsInsulin ResistanceHyperinsulinismGlucose Metabolism DisordersMetabolic DiseasesBody Weight Changes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Department of Human Nutrition

Study Record Dates

First Submitted

September 8, 2010

First Posted

September 13, 2010

Study Start

June 1, 2010

Primary Completion

October 1, 2012

Study Completion

October 1, 2012

Last Updated

June 11, 2014

Record last verified: 2014-06

Locations