Attachment Security as Mediator and Moderator of Outcome in Major Depression
1 other identifier
interventional
134
1 country
1
Brief Summary
In this study, the focus is on an individual's attachment security and its relation to treatment outcome in Major Depression.Adult attachment reflects how one seeks psychological and physical proximity to others for security and protection in times of stress. Researchers typically define four types of attachment security: one secure and three insecure (preoccupied, dismissing, and fearful). Adults with Major Depressive Disorder (MDD) will be randomly assigned to either Interpersonal Psychotherapy (IPT) or to Cognitive Behavior Therapy (CBT). The expectation is that adults with avoidant attachment styles will respond better to CBT, and adults with preoccupied attachment styles will respond better to IPT. Also, in comparison to CBT, outcome in IPT is hypothesized to be more closely related to change in attachment.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Aug 2006
Longer than P75 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 1, 2006
CompletedFirst Submitted
Initial submission to the registry
April 13, 2007
CompletedFirst Posted
Study publicly available on registry
April 17, 2007
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 1, 2010
CompletedStudy Completion
Last participant's last visit for all outcomes
March 1, 2010
CompletedDecember 6, 2011
December 1, 2011
3.5 years
April 13, 2007
December 2, 2011
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
HAMD
baseline and completion
BDI
baseline and completion
Study Arms (2)
1
OTHER2
OTHERInterventions
Eligibility Criteria
You may qualify if:
- or older
- meet the criteria for DSM-IV diagnosis of MDD based on the Structured Interview for DSM-IV, Axis I disorders (SCID-I; First et al., 1995)
- score \> 16 on the 17-item HRSD (Hamilton, 1960).
You may not qualify if:
- Bipolar Disorder
- Schizoaffective Disorder
- Schizophrenia
- Substance Abuse
- Borderline or Antisocial Personality Disorder
- Organic Brain Syndrome
- ECT within the past 6 months
- concurrent active medical illness
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Centre for Addiction and Mental Health
Toronto, Ontario, M5T 1R8, Canada
Related Links
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Carolina McBride, PhD
Centre for Addiction and Mental Health
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Dr. Carolina McBride, C.Psych
Study Record Dates
First Submitted
April 13, 2007
First Posted
April 17, 2007
Study Start
August 1, 2006
Primary Completion
February 1, 2010
Study Completion
March 1, 2010
Last Updated
December 6, 2011
Record last verified: 2011-12