Major Depression
281
17
19
185
Key Insights
Highlights
Success Rate
89% trial completion (above average)
Published Results
45 trials with published results (16%)
Research Maturity
185 completed trials (66% of total)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 40/100
7.8%
22 terminated out of 281 trials
89.4%
+2.9% vs benchmark
25%
69 trials in Phase 3/4
24%
45 of 185 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 185 completed trials
Clinical Trials (281)
Study of Psilocybin Under Anesthesia Controlled by EEG
Inhaled DMT for Major Depressive Disorder
Synaptic Mechanisms of Continuous Theta Burst Stimulation in Depression
Ketamine Alcohol (in Treatment-Resistant Depression)
NIMH Rhythms and Blues Study: A Prospective Natural History Study of Motor Activity, Mood States, and Bipolar Disorder
The Brain-Heart-Gut Connection
Shortened LSD Intervention for Major Depressive Disorder
Treatment Response In ECT Patients
Lifestyle MIND- Feasibility of Wait-list Control
University of Iowa Interventional Psychiatry Service Patient Registry
Assessment of Hedonic and Motivational States in Major Depression ( MOODDIS)
Mechanism of Action Underlying Ketamine's Antidepressant Effects: The AMPA Throughput Theory in Patients With Treatment-Resistant Major Depression
My Coach Connect: An Automated Telephone-based Reporting System for Patients With Mental Illness
Modular Intervention for Depression Study
Accelerated High-Dose tDCS for Depression
Common Factors Group Psychotherapy for General Mental Health Concerns
Transcranial Pulse Stimulation for Depression
Physiologic Monitoring of Antidepressant Response
Study of Sleep Inertia in Major Depressive Disorder by the Psychomotor Vigilance Task
Characterizing Cognitive Decline in Late Life Depression: The ADNI Depression Project