Major Depression
293
23
28
187
Key Insights
Highlights
Success Rate
89% trial completion (above average)
Published Results
45 trials with published results (15%)
Research Maturity
187 completed trials (64% of total)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 40/100
7.5%
22 terminated out of 293 trials
89.5%
+2.9% vs benchmark
24%
69 trials in Phase 3/4
24%
45 of 187 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.6%
Based on 187 completed trials
Clinical Trials (293)
NIMH Rhythms and Blues Study: A Prospective Natural History Study of Motor Activity, Mood States, and Bipolar Disorder
iTBS Versus Standard 10 Hz rTMS for Treatment-Resistant Depression (TRD)
Individual Narratives of Stimulation (ECT and TMS)
Effect of Psychobiotics With Standard Antiddepressants in Treatment of Major Depressive Disorder
Effectiveness of mHealth Post-discharge Intervention for Patients With Severe Mental Illness
Shortened LSD Intervention for Major Depressive Disorder
Single Day of Ultra-accelerated TMS With a Single Dose of NRX-101
Relationship of Peripheral Inflammatory and Neuroprotective Biomarkers With Response to Intermittent Theta Burst Stimulation in Treatment-Resistant Depression
Leucine in Midlife Depression
Mechanism of Action Underlying Ketamine's Antidepressant Effects: The AMPA Throughput Theory in Patients With Treatment-Resistant Major Depression
Study on iTBS Regulating the Reward Circuit Function to Improve Anhedonia in Depression
Evaluation of an 8-week Behavior Skills-based Virtual Reality Program for Adolescents With Depression. (MDD)
Accelerated High-Dose tDCS for Depression
Synaptic Mechanisms of Intermittent Theta Burst Stimulation for Major Depressive Disorder
Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression
RCT of At-Home tDCS for Depression in Pregnancy
EEG Microstate Parameters and Neuroinflammatory Biomarkers in Patients With Treatment-Resistant Major Depressive Disorder Receiving ECT
Effect of Aerobic Exercise on Biomarkers in Depression
Assessing of Behavioral Risk and Response to Electromagnetic and Psychedelic Therapies
Neuroimaging Sleep and Mood in Depression