NCT00322816

Brief Summary

The purpose of this pilot study is to evaluate the use of (1) 'malaria prevalence', (2) 'malaria incidence' and (3) 'malaria mortality' as a measure of malaria transmission in The Gambia, while mosquito insecticides (larvicides) are used to control malaria-carrying mosquitoes. Two thousand children aged 6 months to 10 years of age will be recruited from villages in the study area. They will be monitored over 7 months for the presence of malaria parasites and signs and symptoms of the disease.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2,552

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jun 2006

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 4, 2006

Completed
4 days until next milestone

First Posted

Study publicly available on registry

May 8, 2006

Completed
1 month until next milestone

Study Start

First participant enrolled

June 7, 2006

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2008

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

March 31, 2009

Completed
Last Updated

February 1, 2019

Status Verified

November 1, 2011

Enrollment Period

1.8 years

First QC Date

May 4, 2006

Last Update Submit

January 30, 2019

Conditions

Plasmodium Falciparum Malaria

Keywords

Malaria, Plasmodium falciparum, Gambia, larvicides

Eligibility Criteria

Age6 Months - 10 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • All children living in the defined areas for intervention and between the age of 6 months and 10 years will be invited to participate. No distinctions will be made regarding gender or ethnic group. Moreover, as the target population is all people living in the areas of intervention, and in order of the results from this study to be as generalizable as possible, no distinctions will be made in terms of medical condition or physical health. Moreover, we believe that any children with a medical condition would be especially favored by the participation in the study.

You may not qualify if:

  • None

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Medical Research Council's Laboratories

Fajara, The Gambia

Location

MeSH Terms

Conditions

Malaria, FalciparumMalaria

Condition Hierarchy (Ancestors)

Protozoan InfectionsParasitic DiseasesInfectionsMosquito-Borne DiseasesVector Borne Diseases

Study Design

Study Type
observational
Time Perspective
PROSPECTIVE
Sponsor Type
NIH

Study Record Dates

First Submitted

May 4, 2006

First Posted

May 8, 2006

Study Start

June 7, 2006

Primary Completion

March 31, 2008

Study Completion

March 31, 2009

Last Updated

February 1, 2019

Record last verified: 2011-11

Locations

TH(1)