NCT00322738

Brief Summary

This study will attempt to find out what effect mosquito insecticides have on the transmission of malaria in The Gambia. Eight hundred healthy men and women, aged 18 to 40 years, living in selected villages east of Farafenni town in The Gambia, West Africa will be screened for parasites. About 552 of these people are expected to be free of malaria and will form the study group. These people will participate in the study for 7 months and will be checked for the malaria-causing parasite every two weeks by finger prick blood sample.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2,558

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jun 2006

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 4, 2006

Completed
4 days until next milestone

First Posted

Study publicly available on registry

May 8, 2006

Completed
1 month until next milestone

Study Start

First participant enrolled

June 7, 2006

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2008

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

March 31, 2009

Completed
Last Updated

February 1, 2019

Status Verified

November 1, 2011

Enrollment Period

1.8 years

First QC Date

May 4, 2006

Last Update Submit

January 30, 2019

Conditions

Plasmodium Falciparum Malaria

Keywords

malaria, Plasmodium falciparum, Gambia, larvicides, vector

Eligibility Criteria

Age18 Years - 40 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Healthy adults living in the selected villages who consent to join the study,
  • between the ages of 18 to 40 years old, and
  • free of clinical signs or symptoms of illness at recruitment.

You may not qualify if:

  • Adults who do not consent to join the study,
  • sick men and women (i.e., have clinical signs or symptoms of illness),
  • men and women 41 years or older, or
  • children.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Medical Research Council's Laboratories

Fajara, The Gambia

Location

MeSH Terms

Conditions

Malaria, FalciparumMalaria

Condition Hierarchy (Ancestors)

Protozoan InfectionsParasitic DiseasesInfectionsMosquito-Borne DiseasesVector Borne Diseases

Study Design

Study Type
observational
Time Perspective
PROSPECTIVE
Sponsor Type
NIH

Study Record Dates

First Submitted

May 4, 2006

First Posted

May 8, 2006

Study Start

June 7, 2006

Primary Completion

March 31, 2008

Study Completion

March 31, 2009

Last Updated

February 1, 2019

Record last verified: 2011-11

Locations

TH(1)