NCT00321386|UnknownDMC
Analysis of Clinical Profiles of Chinese Patients With Normal Tension Glaucoma
Parameters for Disease Progression in Chinese Patients With Normal Tension Glaucoma
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Parameters for Disease Progression in Chinese Patients With Normal Tension Glaucoma
Sponsor study identifier
Secondary identifiers
observational
500
1 country
2
Study Start
December 2003
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
December 2008
Actual (reported)Study Completion
December 2012
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
To obtain demographic and baseline ophthalmic parameters (such as Intraocular Pressure profiles, disc morphological characteristics, central corneal thickness, peripapillary retinal nerve fibre layer thickness and its serial changes, visual field changes, severity of any medical associations-e.g. hypertension, migraine, strokes, silent cerebral infarcts) with non-invasive measurements, in Chinese Patients with Normal Tension Glaucoma
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 2012
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
December 2003
Date type not reportedThis date has not been verified as actual or estimated.
May 1, 2006
Actual (reported)May 3, 2006
Actual (reported)December 2008
Actual (reported)December 2012
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Patients with Normal Tension Glaucoma recruited from a teritary University Eye Hospital setting.
Contact the study team to confirm eligibility.
Hong Kong Eye Hospital
Hong Kong, Hong Kong
Prince of Wales Hospital
Hong Kong, Hong Kong
Drance S, Anderson DR, Schulzer M; Collaborative Normal-Tension Glaucoma Study Group. Risk factors for progression of visual field abnormalities in normal-tension glaucoma. Am J Ophthalmol. 2001 Jun;131(6):699-708. doi: 10.1016/s0002-9394(01)00964-3.
Leung DY, Tham CC, Li FC, Kwong YY, Chi SC, Lam DS. Silent cerebral infarct and visual field progression in newly diagnosed normal-tension glaucoma: a cohort study. Ophthalmology. 2009 Jul;116(7):1250-6. doi: 10.1016/j.ophtha.2009.02.003. Epub 2009 May 30.
Blood taking for glaucoma genetics analysis shall be performed.
LEUNG YL Dexter, MBChB, FRCS
Glaucoma Service, Hong Kong Eye Hospital
LAM SC Dennis, MD, FRCOphth
Chinese University of Hong Kong
First Submitted
May 1, 2006
First Posted
May 3, 2006
Study Start
December 2003
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
December 2008
Actual (reported)The Genetic Study of Primary Angle-Closure Glaucoma
Leung DY, Li FC, Kwong YY, Tham CC, Chi SC, Lam DS. Simvastatin and disease stabilization in normal tension glaucoma: a cohort study. Ophthalmology. 2010 Mar;117(3):471-6. doi: 10.1016/j.ophtha.2009.08.016. Epub 2010 Jan 4.
Leung DY, Kwong YY, Li FC, Tham CC, Chi SC, Lam DS. Comparison of the clinical characteristics of normal tension glaucoma patients with pretreatment intraocular pressures in the high-teens and low-teens. Br J Ophthalmol. 2010 May;94(5):663-5. doi: 10.1136/bjo.2009.163014. No abstract available.
Leung DY, Iliev ME, Chan P, Baig N, Chi SC, Tham CC, Lam DS. Pressure-cornea-vascular index (PCVI) for predicting disease progression in normal tension glaucoma. Br J Ophthalmol. 2011 Aug;95(8):1106-10. doi: 10.1136/bjo.2009.175992. Epub 2010 Aug 7.
Study Completion
December 2012
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Last Updated
June 28, 2011
Record last verified: 2011-06
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