Sponsor study identifier
Secondary identifiers
NIH
interventional
15
1 country
1
Study Start
February 2004
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
Not reported
Date not reportedStudy Completion
February 2007
Actual (reported)Varied food intake, disease, and genetic differences result in complex diet-health interactions. In principle, information-rich metabolic analyses combined with bioinformatic tools provide an approach to explore these interactions. This project is a feasibility study of the use of high-resolution 1H-nuclear magnetic resonance (NMR) to study metabolic perturbations induced by a deficiency in sulfur amino acids (SAA). The investigators will 1) test the hypothesis that deficient dietary intake of SAA in humans results in oxidation of reduced glutathione (GSH)/oxidized glutathione (GSSG) redox and 2) determine whether 1H-NMR of blood and urine detects metabolic changes due to SAA deficiency.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
February 2007
Actual (reported)Click on a node to explore related trials.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
February 2004
Date type not reportedThis date has not been verified as actual or estimated.
November 14, 2005
Actual (reported)November 15, 2005
Actual (reported)February 2007
Actual (reported)redox state of the two central low molecular weight thiol-disulfide pools, i.e., GSH/GSSG and cysteine (Cys)/cystine (CySS)
a global metabolic spectrum detectable by H-NMR
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Grouped treatment entry
dietary amino acids; cysteine and methionine
The registry names several treatments. This does not confirm that participants received them together or that they form a single product.
View registry recordEmory University Hospital
Atlanta, Georgia, 30322, United States
Dean P Jones, Ph.D.
Emory University
First Submitted
November 14, 2005
First Posted
November 15, 2005
Study Start
February 2004
Date type not reportedThis date has not been verified as actual or estimated.
Study Completion
February 2007
Actual (reported)An Egg Based Breakfast Maintains Flexibility in Older Adults
Effect of the Dietary Supplement SAMe on Blood Homocysteine Levels
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Last Updated
March 18, 2010
Record last verified: 2010-03
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Source: ClinicalTrials.gov.
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