Sponsor study identifier
interventional
33
0 countries
N/A
Study Start
December 14, 2011
Actual (reported)Primary Completion
October 30, 2013
Actual (reported)Study Completion
October 30, 2013
Actual (reported)Aging is associated with an increased risk for metabolic diseases, such as type 2 diabetes and cardiovascular disease. There is reason to believe that the time of day when specific food groups are eaten affects this risk. The investigators propose that eating foods made up of fat and protein (such as eggs) in the morning for breakfast, rather than foods made up of carbohydrates (such as white-bread toast or sugary cereal) may promote a healthier metabolism. This is because the body is designed to burn fat during times of fasting, such as overnight, during sleep. Thus, the body is not prepared to burn sugar early in the morning, when most people eat breakfast. Studies with mice have shown that a sugary breakfast meal inhibits the ability of the body to burn fat for the entire day. In contrast, a breakfast meal with more fat enabled the animals to burn fat as well as other fuels throughout the day. The ability to burn fat is thought to minimize risk for obesity, as well as related diseases such as type 2 diabetes and heart disease. The purpose of this study is to determine if, in older adult humans, consumption of a lower-carbohydrate breakfast meal (relative to a higher-carbohydrate meal) is associated with a healthier metabolism.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
October 30, 2013
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
December 14, 2011
Actual (reported)October 30, 2013
Actual (reported)October 30, 2013
Actual (reported)May 15, 2017
Actual (reported)May 23, 2017
Actual (reported)Respiratory quotient (RQ, a measure of substrate oxidation)
24 hour respiratory quotient will be measured using whole-room indirect calorimetry
4 weeks
45% fat 35% Carbohydrate 20% protein
60% carbohydrate 20% fat 20% protein
High fat breakfast
Higher carbohydrate breakfast
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Bush NC, Resuehr HES, Goree LL, Locher JL, Bray MS, Soleymani T, Gower BA. A High-Fat Compared with a High-Carbohydrate Breakfast Enhances 24-Hour Fat Oxidation in Older Adults. J Nutr. 2018 Feb 1;148(2):220-226. doi: 10.1093/jn/nxx040.
Barbara Gower, PhD
University of Alabama at Birmingham
33 participants (actual enrollment reported by the registry).
First Submitted
May 15, 2017
First Posted
May 23, 2017
Study Start
December 14, 2011
Actual (reported)Miami Healthy Heart Initiative a Behavioral Study on Cardiovascular Risk Factors
Contact the study team to confirm eligibility.
Primary Completion
October 30, 2013
Actual (reported)Study Completion
October 30, 2013
Actual (reported)Last Updated
May 23, 2017
Record last verified: 2017-05
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: