NCT00333853

Brief Summary

Insulin therapy requires monitoring and frequent review of glucose levels to optimize dosing. Effective presentation and data analysis are essential. We examined HbA1c changes using the OneTouch(R) UltraSmart(R) System (Test Group), an integrated glucose meter and electronic logbook, compared to established meters with paper logbooks (Control Group).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
250

participants targeted

Target at P75+ for not_applicable diabetes

Timeline
Completed

Started Aug 2003

Geographic Reach
1 country

7 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2003

Completed
1.8 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2005

Completed
1 year until next milestone

First Submitted

Initial submission to the registry

June 2, 2006

Completed
4 days until next milestone

First Posted

Study publicly available on registry

June 6, 2006

Completed
Last Updated

May 13, 2008

Status Verified

May 1, 2008

First QC Date

June 2, 2006

Last Update Submit

May 12, 2008

Conditions

Outcome Measures

Primary Outcomes (1)

  • Hemoglobin A1c (HbA1c)

Secondary Outcomes (1)

  • Measured hypoglycemia

Interventions

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Male or female subjects with type 1 or type 2 insulin-treated diabetes mellitus with a baseline HbA1c greater than or equal to 8.0%.
  • The lower age limit for pediatric subjects was at the discretion of the pediatric investigators and their Institutional Review Board (IRBs).
  • The upper age limit for pediatric subjects was 20 years (i.e., not having reached their 21st birthday on date of enrollment).
  • Subjects must have monitored blood glucose at least 2 times per day. - Subject's current blood glucose meter has download capability, however, the subject did not routinely use this capability on his/her own.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (7)

Diabetes and Endocrine Associates

La Jolla, California, 92037, United States

Location

Children's Hospital, Los Angeles

Los Angeles, California, 90027, United States

Location

University of Miami Miller School of Medicine

Miami, Florida, 33136, United States

Location

University of Maryland School of Medicine

Baltimore, Maryland, 21201, United States

Location

Joslin Diabetes Center

Boston, Massachusetts, 02215, United States

Location

Washington University School of Medicine

St Louis, Missouri, 63110, United States

Location

Radiant Research

Portland, Oregon, 97239, United States

Location

Related Publications (1)

  • Laffel LM, Hsu WC, McGill JB, Meneghini L, Volkening LK. Continued use of an integrated meter with electronic logbook maintains improvements in glycemic control beyond a randomized, controlled trial. Diabetes Technol Ther. 2007 Jun;9(3):254-64. doi: 10.1089/dia.2006.0021.

MeSH Terms

Conditions

Diabetes Mellitus

Condition Hierarchy (Ancestors)

Glucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Study Officials

  • Lori Laffel, MD, MPH

    Joslin Diabetes Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY

Study Record Dates

First Submitted

June 2, 2006

First Posted

June 6, 2006

Study Start

August 1, 2003

Study Completion

June 1, 2005

Last Updated

May 13, 2008

Record last verified: 2008-05

Locations