Experience and Enhancement: Improving Colonoscopic Polyp Detection

NCT00237276 | Unknown

• 1 other identifier: 05/CL05/70
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

The study looks at 2 hypotheses in 2 patient groups:

1. 1.Are more experienced endoscopists better at detecting subtle lesions (polyps) on the lining of the colon (large bowel) than less experienced endoscopists?
2. 2.Do existing and new techniques that can highlight lesions on the lining of the bowel improve endoscopists ability to spot them? This will be tested using video footage of endoscopies from 2 patient groups: those with a normal colon linig and those with colitis (bowel lining inflamation)

Conditions

Polyps

Keywords

colonoscopy, chromoendoscopy, autoflurescence, narrow band imaging, high definition endoscopy, colorectal cancer, colitis, polyp, DALM, adenoma, video

Outcome Measures

Primary Outcomes (1)

• The difference in adenoma detection rate on video between consultants endoscopist vs. trainee endoscopists who have performed more than 200 endoscopies vs. trainee endospopists who have performed less than 200 endoscopies

Secondary Outcomes (2)

• For each technique:

• differences in adenoma detection rate between endoscopist of varying abilities with and without techniques to highlight polyps. Differences in adenoma detection rate in terms of esperience.

Interventions

colonoscopy PROCEDURE

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients: over 18 years of age, with clinical indication for colonoscopy who are considered by the endoscopist to be fit for the procedure
• Endoscopists who have started colonoscopy training on a recognised training rotation. Consultants who perform colonoscopy regularly

You may not qualify if:

• patients under 18 years, patients with previous colorectal surgery or known familial polyposis, patients unable to give informed consent, pregnant patients, patients for whom coloscope insertion was difficult or uncomfortable, patients whose colon is not sufficiently cleared of stool, those unwilling to participate

Sponsors & Collaborators

• London North West Healthcare NHS Trust: lead

Study Sites (1)

North West London Hospitals NHS Trust - St Mark's Hospital

London, HA1 3Uj, United Kingdom

RECRUITING

MeSH Terms

Conditions

Polyps; Colorectal Neoplasms; Colitis; Adenoma

Interventions

Colonoscopy

Condition Hierarchy (Ancestors)

Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Intestinal Neoplasms; Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Colonic Diseases; Intestinal Diseases; Rectal Diseases; Gastroenteritis; Neoplasms, Glandular and Epithelial; Neoplasms by Histologic Type

Intervention Hierarchy (Ancestors)

Endoscopy, Gastrointestinal; Endoscopy, Digestive System; Diagnostic Techniques, Digestive System; Diagnostic Techniques and Procedures; Diagnosis; Endoscopy; Diagnostic Techniques, Surgical; Digestive System Surgical Procedures; Surgical Procedures, Operative; Minimally Invasive Surgical Procedures

Study Officials

• Brian Saunders, MD, FRCP

  London North West Healthcare NHS Trust

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Brian Saunders, MD, FRCP

CONTACT

b.saunders@imperial.ac.uk

James East, MBChB, MRCP

CONTACT

020 8235 4033

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: October 10, 2005
• First Posted: October 12, 2005
• Study Start: October 1, 2005
• Last Updated: September 24, 2007

Record last verified: 2007-09

Locations

GB (1)