NCT01923155

Brief Summary

There is no theoretical or practical reason why non-medical personnel such as nurses could not be trained to perform diagnostic colonoscopy with comparable proficiency as medical endoscopists. Nurse endoscopists have been widely accepted in the United Kingdom for the past 15 years as a valuable resource to cope with the increasing demand for endoscopic service, in particular diagnostic colonoscopy for colorectal screening. A pilot study performed in Hong Kong in 2008 has shown that endoscopy nurses can be trained to perform diagnostic endoscopy safely and reliably. This study aims to demonstrate that properly trained nurse endoscopists have a comparable proficiency in performing colonoscopy procedures as their medical counterparts.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
731

participants targeted

Target at P75+ for not_applicable colorectal-cancer

Timeline
Completed

Started Mar 2012

Shorter than P25 for not_applicable colorectal-cancer

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2012

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2013

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2013

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

August 12, 2013

Completed
3 days until next milestone

First Posted

Study publicly available on registry

August 15, 2013

Completed
Last Updated

August 15, 2013

Status Verified

August 1, 2013

Enrollment Period

1.3 years

First QC Date

August 12, 2013

Last Update Submit

August 14, 2013

Conditions

Outcome Measures

Primary Outcomes (1)

  • Adenoma detection rate

    Up to 3 months

Secondary Outcomes (6)

  • Cecal intubation RATE

    Up to 3 months

  • Withdrawal time

    Up to 3 months

  • Complication rate

    Up to 3 months

  • Patients pain score

    Up to 3 months

  • Patients overall satisfactory score

    Up to 3 months

  • +1 more secondary outcomes

Study Arms (2)

Nurse endoscopists

ACTIVE COMPARATOR

Colonoscopy performed by nurse endoscopists supervised by senior medical endoscopists

Procedure: Colonoscopy

Medical endoscopists

ACTIVE COMPARATOR

Colonoscopy performed by senior medical endoscopists

Procedure: Colonoscopy

Interventions

ColonoscopyPROCEDURE
Medical endoscopistsNurse endoscopists

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • \. Subjects receiving screening colonoscopy
  • \. Age ≥ 18
  • \. Informed consent

You may not qualify if:

  • \. Subjects have undergone colonoscopy in the past 5 years
  • \. Patients with prior colorectal surgery
  • \. Subjects with a personal history of inflammatory bowel disease, colon adenoma or cancer or family history of Familial Adenomatous Polyposis or Familial non-polyposis syndrome
  • \. Pregnant or lactating women
  • \. Lack of consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Combined Endoscopy Unit, Alice Ho Miu Ling Nethersole Hospital

Tai Po, Hong Kong

Location

Related Publications (1)

  • Hui AJ, Lau JY, Lam PP, Chui AO, Fan AS, Lam TY, Tse YK, Tang RS, Ng SC, Wu JC, Ching JY, Wong MC, Chan FK, Sung J. Comparison of colonoscopic performance between medical and nurse endoscopists: a non-inferiority randomised controlled study in Asia. Gut. 2015 Jul;64(7):1058-62. doi: 10.1136/gutjnl-2013-306293. Epub 2014 Dec 18.

MeSH Terms

Conditions

Colorectal Neoplasms

Interventions

Colonoscopy

Condition Hierarchy (Ancestors)

Intestinal NeoplasmsGastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesColonic DiseasesIntestinal DiseasesRectal Diseases

Intervention Hierarchy (Ancestors)

Endoscopy, GastrointestinalEndoscopy, Digestive SystemDiagnostic Techniques, Digestive SystemDiagnostic Techniques and ProceduresDiagnosisEndoscopyDiagnostic Techniques, SurgicalDigestive System Surgical ProceduresSurgical Procedures, OperativeMinimally Invasive Surgical Procedures

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr

Study Record Dates

First Submitted

August 12, 2013

First Posted

August 15, 2013

Study Start

March 1, 2012

Primary Completion

June 1, 2013

Study Completion

June 1, 2013

Last Updated

August 15, 2013

Record last verified: 2013-08

Locations